2026

Vol. 14 (2026)

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Reviews in Medical Informatics

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Large Language Model–Based Virtual Patient Systems for History-Taking in Medical Education: Comprehensive Systematic Review

Dongliang Li, Syaheerah Lebai Lutfi

JMIR Med Inform 2026 (Jan 02); 14:e79039

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Machine Learning

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Automated Classification of Lymphoma Subtypes From Histopathological Images Using a U-Net Deep Learning Model: Comparative Evaluation Study

Jin Zhao, Xiaolian Wen, Li Ma, Liping Su

JMIR Med Inform 2026 (Jan 06); 14:e72679

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Deep Learning for Dynamic Prognostic Prediction in Minimally Invasive Surgery for Intracerebral Hemorrhage: Model Development and Validation Study

Jingxuan Wang, Jian Shi, Qing Ye, Danyang Chen, Yuhao Sun, Chao Pan, Yingxin Tang, Ping Zhang, Zhouping Tang

JMIR Med Inform 2026 (Jan 07); 14:e86327

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Development of Venous Thromboembolism Risk Prediction Models Based on Whole Blood Gene Expression Profiling Using 20 Machine Learning Algorithms: Comprehensive Analysis Study

Yedong Huang, Xiaoyun Chen, Guannan Bai, Yajun Zhao, Dapeng Kuang, Lin Zhang, Wei Lu

JMIR Med Inform 2026 (Jan 16); 14:e75565

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Machine Learning Prediction of Pharmacogenetic Testing Uptake Among Opioid-Prescribed Patients Using Electronic Health Records: Retrospective Cohort Study

Mohammad Yaseliani, Je-Won Hong, Jiang Bian, Larisa Cavallari, Julio D Duarte, Danielle Nelson, Wei-Hsuan Lo-Ciganic, Khoa Anh Nguyen, Md Mahmudul Hasan

JMIR Med Inform 2026 (Jan 21); 14:e81048

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Secondary Use of Clinical Data for Research and Surveillance

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Impact of Age on Hospital Outcomes Following Minimally Invasive Posterior Lumbar Interbody Fusion: Retrospective Analysis of the Nationwide Inpatient Sample Database from 2016 to 2020

Yu-Jun Lin, Fu-Yuan Shih, Jin-Fu Huang, Chun-Wei Ting, Yu-Chin Tsai, Lin Chang, Yu-Hua Huang, Ming-Jung Chuang

JMIR Med Inform 2026 (Jan 06); 14:e76424

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AI Language Models in Health Care

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Large Language Models in Patient Health Communication for Atherosclerotic Cardiovascular Disease: Pilot Cross-Sectional Comparative Analysis

Pengfei Li, Yinfei Xu, Xiang Liu, Zhean Shen, Yi Wang, Xinyi Lv, Ziyi Lu, Hui Wu, Jiaqi Zhuang, Yan Chen

JMIR Med Inform 2026 (Jan 07); 14:e81422

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Standards and Interoperability

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Applicability of Existing Gender Scores for German Clinical Research Data: Scoping Review and Data Mapping

Lea Schindler, Hilke Beelich, Elpiniki Katsari, Daniele Liprandi, Sylvia Stracke, Dagmar Waltemath

JMIR Med Inform 2026 (Jan 08); 14:e74162

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Viewpoints on and Experiences with Digital Technologies in Health

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Ethical Imperatives for Retrieval-Augmented Generation in Clinical Nursing: Viewpoint on Responsible AI Use

Xinyi Tu, Chenghao Shi, Peilin Qian, Lizhu Wang

JMIR Med Inform 2026 (Jan 09); 14:e79922

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Ambient AI Scribes and AI-Driven Documentation Technologies

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Large Language Model–Enabled Editing of Patient Audio Interviews From “This Is My Story” Conversations: Comparative Study

Bikram Bains, Sampath Rapuri, Edgar Robitaille, Jonathan Wang, Arnav Khera, Catalina Gomez, Eduardo Reyes, Cole Perry, Jason Wilson, Elizabeth Tracey

JMIR Med Inform 2026 (Jan 09); 14:e80205

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Electronic Health Records

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Exploring Factors Associated With the Stalled Implementation of a Ground-Up Electronic Health Record System in South Africa: Qualitative Insights From the E-Tick Case Study Using the Consolidated Framework for Implementation Research (CFIR)

Campion Zharima, Frances Griffiths, Jane Goudge

JMIR Med Inform 2026 (Jan 12); 14:e73831

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Development of Quality Indicators for the Correct Use of Electronic Medical Records in Primary Care: Modified Delphi Study

Rico Paridaens, Steve Van den Bulck, Michel De Jonghe, Benjamin Fauquert, Liesbeth Meel, Willem Raat, Bert Vaes

JMIR Med Inform 2026 (Jan 19); 14:e80057

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Genomics and Bioinformatics for Clinical Use

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Neutrophil Percentage–to-Albumin Ratio as a Novel Prognostic Biomarker in Adult Diffuse Gliomas: Retrospective Study Integrating 3 Machine Learning Models and Cox Regression

Congcong Zhu, Jiyang An, Lili Zhou

JMIR Med Inform 2026 (Jan 13); 14:e79945

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Ontologies, Classifications, and Coding

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Large Language Models for Psychiatric Diagnosis Based on Multicenter Real-World Clinical Records: Comparative Study

Maoqian Sun, Jia Yu, Zhuhong Long, Yun Yang, Tao Xiao, Jiaquan Liang, Jun Feng, Huaili Deng, Guoping Huang

JMIR Med Inform 2026 (Jan 13); 14:e77699

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Imaging Informatics

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Nomograms Based on X-Ray Radiomics for Predicting Pain Progression in Knee Osteoarthritis Using Data From the Foundation for the National Institutes of Health: Development and Validation Study

Yingwei Sun, Jing Liu, Chunbo Deng, Chengbao Peng, Shinong Pan, Xueyong Liu

JMIR Med Inform 2026 (Jan 14); 14:e78338

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Two-Minute Deep Learning–Powered Brain Quantitative Mapping: Accelerating Clinical Imaging With Synthetic Magnetic Resonance Imaging

Yawen Liu, Hongxia Yin, Zuofeng Zheng, Wenjuan Liu, Tingting Zhang, Linkun Cai, Haijun Niu, Han Lv, Zhenghan Yang, Zhenchang Wang, Pengling Ren

JMIR Med Inform 2026 (Jan 23); 14:e79389

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Case Study

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Developing a Suicide Risk Prediction Algorithm Using Electronic Health Record Data in Mental Health Care: Real-World Case Study

Linda Hummel, Karin C A G Lorenz-Artz, Joyce J P A Bierbooms, Inge M B Bongers

JMIR Med Inform 2026 (Jan 14); 14:e74240

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Decision Support for Health Professionals

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Mild Cognitive Impairment Detection System Based on Unstructured Spontaneous Speech: Longitudinal Dual-Modal Framework

Yu-Shan Liao, Thiri Wai, Ting-Yun Liao, Ho-Ling Chang, Yu-Ling Chang, Li-Chen Fu

JMIR Med Inform 2026 (Jan 15); 14:e80883

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Computer-Aided Diagnosis

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Prompting and Fine-Tuning Large Language Models for Parkinson Disease Diagnosis: Comparative Evaluation Study Using the PPMI Structured Dataset

Hyun-Ji Shin, Young Jin Jeong, Sungmin Jun, Do-Young Kang

JMIR Med Inform 2026 (Jan 15); 14:e77561

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Methods and Instruments in Medical Informatics

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Effects of Image Degradation on Deep Neural Network Classification of Scaphoid Fracture Radiographs: Comparison Study of Different Noise Types

Chihung Lin, Alfred P Yoon, Chien-Wei Wang, Tung Chao, Kevin C Chung, Chang-Fu Kuo

JMIR Med Inform 2026 (Jan 22); 14:e65596

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