Computer-Aided Diagnosis

Performance of Large Language Models in Diagnosing Rare Hematologic Diseases and the Impact of Their Diagnostic Outputs on Physicians: Combined Retrospective and Prospective Study

Hongbin Yu, Tian Chen, Xin Zhang, Yunfan Yang, Qinyu Liu, Chenlu Yang, Kai Shen, He Li, Wenjiao Tang, Xushu Zhong, Xiao Shuai, Xinmei Yu, Yi Liao, Chiyi Wang, Huanling Zhu, Yu Wu

J Med Internet Res 2025 (Oct 09); 27:e77334

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A Vision-Language–Guided Multimodal Fusion Network for Glottic Carcinoma Early Diagnosis: Model Development and Validation Study

Zhaohui Jin, Yi Shuai, Yun Li, Mianmian Chen, Yumeng Liu, Wenbin Lei, Xiaomao Fan

JMIR Med Inform 2025 (Oct 08); 13:e74902

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YOLOv12 Algorithm-Aided Detection and Classification of Lateral Malleolar Avulsion Fracture and Subfibular Ossicle Based on CT Images: Multicenter Study

Jiayi Liu, Peng Sun, Yousheng Yuan, Zihan Chen, Ke Tian, Qian Gao, Xiangsheng Li, Liang Xia, Jun Zhang, Nan Xu

JMIR Med Inform 2025 (Oct 03); 13:e79064

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Identification of Syndrome Types in Patients With Pancreatic Cancer From Free Text in Electronic Medical Records: Model Development and Validation

He Ba, Haojie Du, Chienshan Cheng, Yuan Zhang, Linjie Ruan, Zhen Chen

JMIR Form Res 2025 (Oct 03); 9:e70602

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Differential Diagnosis Assessment in Ambulatory Care With a Digital Health History Device: Pseudorandomized Study

Beth Healey, Adrien Schwitzguebel, Herve Spechbach

JMIR Form Res 2025 (Oct 01); 9:e56384

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Speech Emotion Recognition in Mental Health: Systematic Review of Voice-Based Applications

Eric Jordan, Raphaël Terrisse, Valeria Lucarini, Motasem Alrahabi, Marie-Odile Krebs, Julien Desclés, Christophe Lemey

JMIR Ment Health 2025 (Sep 30); 12:e74260

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Handwriting in Mild Cognitive Impairment: Reliability Assessment and Machine Learning–Based Screening

Simone Toffoli, Carlo Abbate, Francesca Lunardini, Edoardo Corno, Nicholas Diani, Alessia Gallucci, Emanuele Tomasini, Pietro Davide Trimarchi, Simona Ferrante

JMIR Aging 2025 (Sep 23); 8:e73074

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Machine Learning and Shapley Additive Explanations Value Integration for Predicting the Prognostic of Anti-N-Methyl-D-Aspartate Receptor Encephalitis: Model Development and Evaluation Study

Jia Wang, Haotian Wu, Han Cai, YingXiang Wang, Jian Gu

JMIR Med Inform 2025 (Sep 22); 13:e75020

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Diagnostic Performance of Computed Tomography–Based Artificial Intelligence for Early Recurrence of Cholangiocarcinoma: Systematic Review and Meta-Analysis

Jie Chen, Jianxin Xi, Tianyu Chen, Lulu Yang, Kaijia Liu, Xiaobo Ding

J Med Internet Res 2025 (Sep 18); 27:e78306

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Fusion of X-Ray Images and Clinical Data for a Multimodal Deep Learning Prediction Model of Osteoporosis: Algorithm Development and Validation Study

Jun Tang, Xiang Yin, Jiangyuan Lai, Keyu Luo, Dongdong Wu

JMIR Med Inform 2025 (Sep 18); 13:e70738

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Leveraging Smart Bed Technology to Detect COVID-19 Symptoms: Case Study

Gary Garcia-Molina, Dmytro Guzenko, Susan DeFranco, Mark Aloia, Rajasi Mills, Faisal Mushtaq, Virend K Somers

JMIR AI 2025 (Sep 17); 4:e64018

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Comparative Diagnostic Performance of a Multimodal Large Language Model Versus a Dedicated Electrocardiogram AI in Detecting Myocardial Infarction From Electrocardiogram Images: Comparative Study

Haemin Lee, Sooyoung Yoo, Joonghee Kim, Youngjin Cho, Dongbum Suh, Keehyuck Lee

JMIR AI 2025 (Sep 17); 4:e75910

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Using Wearable Device and Machine Learning to Predict Mood Symptoms in Bipolar Disorder: Development and Usability Study

Chia-Tung Wu, Ming H Hsieh, I-Ming Chen, Lian-Yin Jhao, Ding-Shan Liu, Ssu-Ming Wang, Chia-Ting Wu, Yi-Ling Chien

JMIR Med Inform 2025 (Sep 16); 13:e66277

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Machine Learning Approach for Frailty Detection in Long-Term Care Using Accelerometer-Measured Gait and Daily Physical Activity: Model Development and Validation Study

Xiaoping Zheng, Ziwei Zeng, Kimberley S van Schooten, Yijian Yang

JMIR Aging 2025 (Sep 15); 8:e77140

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Prompt Engineering in Clinical Practice: Tutorial for Clinicians

Jialin Liu, Fang Liu, Changyu Wang, Siru Liu

J Med Internet Res 2025 (Sep 15); 27:e72644

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Enhancing Oral Health Diagnostics With Hyperspectral Imaging and Computer Vision: Clinical Dataset Study

Paul Römer, Jean-Jacques Ponciano, Katharina Kloster, Fabia Siegberg, Bastian Plaß, Shankeeth Vinayahalingam, Bilal Al-Nawas, Peer W Kämmerer, Thomas Klauer, Daniel Thiem

JMIR Med Inform 2025 (Sep 11); 13:e76148

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Diagnostic and Screening AI Tools in Brazil’s Resource-Limited Settings: Systematic Review

Leticia Medeiros Mancini, Luiz Eduardo Vanderlei Torres, Jorge Artur P de M Coelho, Nichollas Botelho da Fonseca, Pedro Fellipe Dantas Cordeiro, Samara Silva Noronha Cavalcante, Diego Dermeval

JMIR AI 2025 (Sep 10); 4:e69547

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Interpretable Artificial Intelligence Analysis of Functional Magnetic Resonance Imaging for Migraine Classification: Quantitative Study

Guohao Li, Hao Yang, Li He, Guojun Zeng

JMIR Med Inform 2025 (Sep 03); 13:e72155

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Rapidly Benchmarking Large Language Models for Diagnosing Comorbid Patients: Comparative Study Leveraging the LLM-as-a-Judge Method

Peter Sarvari, Zaid Al-fagih

JMIRx Med 2025 (Aug 29); 6:e67661

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A Machine Learning Algorithm With an Oversampling Technique in Limited Data Scenarios for the Prediction of Present and Future Restorative Treatment Need: Development and Validation Study

Elina Väyrynen, Otso Tirkkonen, Henna Tiensuu, Jaakko Suutala, Vuokko Anttonen, Marja-Liisa Laitala, Katri Kukkola, Saujanya Karki

JMIR Med Inform 2025 (Aug 28); 13:e75117

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