Tools, Programs and Algorithms

Dynamic Personalized Optimization: An AI Functionality Framework for Digital Therapeutics

Dohyoung Rim

JMIR Med Inform 2026 (Mar 18); 14:e75256

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Rectal Cancer Radiotherapy Response Prediction: Retrospective Study of Development of a Deep Learning–Based Radiomics Model

Yiqun Li, Hengchang Liu, Qiang Wei, Zhenqi Wang, Zhen Hu

JMIR Med Inform 2026 (Mar 17); 14:e77313

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Causal Discovery in Observational Medical Research: Scoping Review

Zuting Liu, Tian Luo, Hailin Ma, Jiali Mo, Xia Yang, Zhenglong Huang, Jingkun Li, Jie Kuang

JMIR Med Inform 2026 (Mar 13); 14:e82499

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AI-Based Personalized Therapy With Clinical Intelligence and Radiomics (SPOILS) for Patients With Low Back Pain: Prospective Observational Study

Purushottam Kumar, Suyash Singh, Bunil Kumar Balabantaray

JMIR AI 2026 (Mar 11); 5:e83322

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Integrating GPT-4o Into Data Mining in Neurosurgery: Feasibility and Proof-of-Concept Study

Arthur Henrique Almeida Sales, Jürgen Beck, Jürgen Grauvogel

JMIR Form Res 2026 (Mar 09); 10:e77114

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Automated Annotation of Pain Chronicity in Patients With Back Pain by Using Electronic Health Records: Retrospective Study

Simran Ajay Kanal, Jeannie Bailey, Jeffrey Lotz, Aaron Scheffler, Thomas Peterson

JMIR Form Res 2026 (Mar 05); 10:e63198

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Important Ethical, Technical, and Epidemiological Considerations in an AI Tool Production (ETEPAI): Scoping Review

Boon How Chew, Kee Yuan Ngiam

JMIR AI 2026 (Mar 05); 5:e80340

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Scalable and Privacy-Conscious End-to-End Processing of Large-Scale Clinical Data for Precision Medicine: Empirical Evaluation Study

Jungwoo Lee, Sangwon Hwang, Kyu Hee Lee

JMIR Med Inform 2026 (Mar 04); 14:e83487

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AI Models to Reduce Surgical Complications Through Intraoperative Video Analysis: Protocol for a Prospective Cohort Study

António Sampaio Soares, Sophia Bano, Laura T Castro, Margarida Pascoal, Ricardo Rocha, Paulo Alves, Paulo Mira, Joao Costa, Manish Chand, Danail Stoyanov, Catarina Barata

JMIR Res Protoc 2026 (Feb 26); 15:e62734

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Temporal Annotation of German Clinical Language in Real and Synthetic Clinical Documents: Corpus Development and Baseline Tagger Validation Study

Luise Modersohn, Udo Hahn

J Med Internet Res 2026 (Feb 25); 28:e71458

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Noninvasive Measurement of Cerebrospinal Fluid Flow in Shunted Hydrocephalus: Protocol for Scanner Calibration and Multisite Data Collection

Jason M Toliao, Matthew T Borzage, Pradip P Chaudhari, Joseph H Ha, Isabella Friedli, Madison E Gutierrez, Meghan Drastal, Peter Calabrese, Eamon K Doyle, Isabel Torres, Jacob Al-Husseini, Clio González-Zacarías, John C Wood, Jason Hauptman, J Gordon McComb, Stefan Blüml, Peter A Chiarelli

JMIR Res Protoc 2026 (Feb 20); 15:e85918

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Machine Learning for Predicting Stroke Risk Stratification Using Multiomics Data: Systematic Review

Hae Young Yoo, Hyerim Shin, Eun-Jung Kim, Youn-Jung Son

J Med Internet Res 2026 (Feb 19); 28:e85654

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Effectiveness of Step Goal Personalization Strategies on Physical Activity in a Mobile Health App: A Field Study

Xia Liu, Tammo H A Bijmolt, Marijke C Leliveld, Ernst H Noppers

JMIR Mhealth Uhealth 2026 (Feb 18); 14:e81779

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Developing a Multimodal Screening Algorithm for Mild Cognitive Impairment and Early Dementia in Home Health Care: Protocol for a Cross-Sectional Case-Control Study Using Speech Analysis, Large Language Models, and Electronic Health Records

Maryam Zolnoori

JMIR Res Protoc 2026 (Feb 02); 15:e82731

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Leveraging Large Language Models for Early Detection of Anomaly Work Injury Cases: Data-Driven Approach to Rehabilitation Efficiency

Peter Q Chen, Hayley Y W Gu, Heidi K Y Lo, Wing Chung Chang, Cameron J M Lai, Sun H S Lai, Andy S K Cheng, Peter H F Ng

JMIR Rehabil Assist Technol 2026 (Jan 30); 13:e80607

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Scaling Wireless Continuous Vital Sign Monitoring Across an 8-Hospital Health System: Digital Health Implementation Report

Ngoc-Anh Nguyen, Grace Lee, Brendan Holderread, Terrie Holman, Sarah Pletcher, Roberta Schwartz

JMIR Med Inform 2026 (Jan 26); 14:e78216

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Multi-Evidence Clinical Reasoning With Retrieval-Augmented Generation for Emergency Triage: Retrospective Evaluation Study

Hang Sheung Wong, Tsz Kwan Wong

JMIR Med Inform 2026 (Jan 26); 14:e82026

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Privacy-Preserving Collaborative Diabetes Prediction in Heterogeneous Health Care Systems: Algorithm Development and Validation of a Secure Federated Ensemble Framework

Md Rakibul Hasan, Juan Li

JMIR Diabetes 2026 (Jan 26); 11:e79166

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Comprehensive Pediatric Health Risk Stratification Using an AI-Driven Framework in Children Aged 2 to 8 Years: Design and Validation Study

Jundan Chen, Zhihe Mao

JMIR Med Inform 2026 (Jan 26); 14:e80163

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Development of Venous Thromboembolism Risk Prediction Models Based on Whole Blood Gene Expression Profiling Using 20 Machine Learning Algorithms: Comprehensive Analysis Study

Yedong Huang, Xiaoyun Chen, Guannan Bai, Yajun Zhao, Dapeng Kuang, Lin Zhang, Wei Lu

JMIR Med Inform 2026 (Jan 16); 14:e75565

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