TY  - JOUR
AU  - Yang, Zhongbao
AU  - Xu, Shan-Shan
AU  - Liu, Xiaozhu
AU  - Xu, Ningyuan
AU  - Chen, Yuqing
AU  - Wang, Shuya
AU  - Miao, Ming-Yue
AU  - Hou, Mengxue
AU  - Liu, Shuai
AU  - Zhou, Yi-Min
AU  - Zhou, Jian-Xin
AU  - Zhang, Linlin
PY  - 2025
DA  - 2025/3/12
TI  - Large Language Model–Based Critical Care Big Data Deployment and Extraction: Descriptive Analysis
JO  - JMIR Med Inform
SP  - e63216
VL  - 13
KW  - big data
KW  - critical care–related databases
KW  - database deployment
KW  - large language model
KW  - database extraction
KW  - intensive care unit
KW  - ICU
KW  - GPT
KW  - artificial intelligence
KW  - AI
KW  - LLM
AB  - Background: Publicly accessible critical care–related databases contain enormous clinical data, but their utilization often requires advanced programming skills. The growing complexity of large databases and unstructured data presents challenges for clinicians who need programming or data analysis expertise to utilize these systems directly. Objective: This study aims to simplify critical care–related database deployment and extraction via large language models. Methods: The development of this platform was a 2-step process. First, we enabled automated database deployment using Docker container technology, with incorporated web-based analytics interfaces Metabase and Superset. Second, we developed the intensive care unit–generative pretrained transformer (ICU-GPT), a large language model fine-tuned on intensive care unit (ICU) data that integrated LangChain and Microsoft AutoGen. Results: The automated deployment platform was designed with user-friendliness in mind, enabling clinicians to deploy 1 or multiple databases in local, cloud, or remote environments without the need for manual setup. After successfully overcoming GPT’s token limit and supporting multischema data, ICU-GPT could generate Structured Query Language (SQL) queries and extract insights from ICU datasets based on request input. A front-end user interface was developed for clinicians to achieve code-free SQL generation on the web-based client. Conclusions: By harnessing the power of our automated deployment platform and ICU-GPT model, clinicians are empowered to easily visualize, extract, and arrange critical care–related databases more efficiently and flexibly than manual methods. Our research could decrease the time and effort spent on complex bioinformatics methods and advance clinical research. 
SN  - 2291-9694
UR  - https://medinform.jmir.org/2025/1/e63216
UR  - https://doi.org/10.2196/63216
DO  - 10.2196/63216
ID  - info:doi/10.2196/63216
ER  -