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Methods and Instruments in Medical Informatics (437) New Methods (1872) Tools, Programs and Algorithms (610) Electronic Health Records (1799) Secondary Use of Clinical Data for Research and Surveillance (664) Machine Learning (3353)

Published on in Vol 13 (2025)

Preprints (earlier versions) of this paper are available at https://preprints.jmir.org/preprint/79307, first published .
Doctor's desk with computer showing patient appointments, thermometer, and stethoscope

Methods for Addressing Missingness in Electronic Health Record Data for Clinical Prediction Models: Comparative Evaluation

Methods for Addressing Missingness in Electronic Health Record Data for Clinical Prediction Models: Comparative Evaluation

Authors of this article:

Jean Digitale1, 2 Author Orcid Image ;   Deborah Franzon3 Author Orcid Image ;   Mark J Pletcher2 Author Orcid Image ;   Charles E McCulloch2 Author Orcid Image ;   Efstathios D Gennatas2 Author Orcid Image
Article Authors Cited by (24) Tweetations Metrics

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  14. Zhao X, Zhang Y, Tang H, Long J, Dong H, Kuang G, Song J. Prediction models for infection after kidney transplantation: a systematic review. Frontiers in Medicine 2026;13 View
  15. Chi H, Liu X, Yan Y, Wang L, Luo P, Su L, Jiang L, Zhou X, Huang G, Jiang Y, Yin S, Su K, Chen H, Zhang G, Zhang P, Zhang H, Ye B, Cao Q, Liu J, Khadka V, Yang H, Yang G, Xu J, Wang P, Wang X, Xia Z, Li X, Deng Y, Li Z, Xu K. Trustworthy AI for disease pathogenesis and precision medicine: A disease-agnostic framework from data to deployment. Genes & Diseases 2026:102480 View
  16. Tsai Y, Wu Y, Yu Y, Chen Y, Yang Y, Lo Y. Development and Temporal External Validation of a Parsimonious, Interpretable Machine Learning Model for Predicting 6-Month Mortality in Long-Term Care Facilities: A Retrospective Cohort Study. JMIR Aging 2026;9:e94567 View
  17. Purwitasari D, Nursalam , Qona'ah A, Amaliah B, Navastara D, Priambodo T. Cardiovascular Disease Classification Using K-Nearest Neighbors with Multiple Imputation by Chained Equations (KNN-MICE). Engineering, Technology & Applied Science Research 2026;16(5):39769 View
  18. T O, R P, V K, T S, K K, K S. Comparative Evaluation of Tree-Based Algorithms for Postpartum Mental Health Risk: a Methodological Benchmark. International Research Journal of Multidisciplinary Technovation 2026:296 View
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  21. Leon M, Ruaengsri C, He H, Pelletier G, Flores M, Bethencourt D, Shudo Y. National Evaluation of the Updated ISHLT Early Graft Dysfunction Framework in Adult Heart Transplantation: Diagnostic Migration, Attrition, and Prognostic Implications. Transplantation 2026 View

Conference Proceedings

  1. Mohamed S. 2026 International Conference on Circuit, Systems and Communication (ICCSC). Supervised Binary Label Imputation via Correlated Features and Logistic Regression View
  2. Panghe A, Tassy L, Sun C, Protopopescu C, Urena R. 2026 IEEE 39th International Symposium on Computer-Based Medical Systems (CBMS). Benchmark Pipeline for Missing Data Imputation in Oncological Electronic Health Records View
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