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This paper is in the following e-collection/theme issue:

Natural Language Processing (1228) Clinical Information and Decision Making (3544) Ontologies, Classifications, and Coding (417) Artificial Intelligence (4544) Artificial Intelligence, Machine Learning, and Natural Language Processing for Public Health (150) Generative Language Models Including ChatGPT (1421) AI Language Models in Health Care (696)

Published on in Vol 13 (2025)

Preprints (earlier versions) of this paper are available at https://preprints.jmir.org/preprint/77837, first published .
Scientist examines DNA on computer screen in a lab

Large Language Model–Enhanced Drug Repositioning Knowledge Extraction via Long Chain-of-Thought: Development and Evaluation Study

Large Language Model–Enhanced Drug Repositioning Knowledge Extraction via Long Chain-of-Thought: Development and Evaluation Study

Authors of this article:

Hongyu Kang1, 2 Author Orcid Image ;   Jiao Li2 Author Orcid Image ;   Li Hou2 Author Orcid Image ;   Xiaowei Xu2 Author Orcid Image ;   Si Zheng2 Author Orcid Image ;   Qin Li1 Author Orcid Image
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  1. Chew B. Our AI-Powered Discoveries Are Trapped in a Predigital System. Journal of Medical Internet Research 2026;28:e96018 View
  2. Mou Z, Tian Z, Jin J, Yu H, Huang Y. Reviewing the Computational Landscape of Drug Repurposing: Evolution from Structure-Based Methods to LLM-Based Methods. Biomolecules 2026;16(6):830 View
  3. Ivanov A, Ruseva V, Hababa-Ivanova I, Getova-Kolarova V, Lebanova H, Getov I. From Laboratory to Patient Access: A Scoping Review of the Multi-Dimensional Challenges in Drug Repurposing. Pharmacy 2026;14(3):85 View

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  1. Verol F, Regino A, Zagatti F, Rosa F, Reis J, Bonacin R. Anais do XXVI Simpósio Brasileiro de Computação Aplicada à Saúde (SBCAS 2026). Domain-Specific Fine-Tuning of Large Language Models for Pharmacological Question Answering View