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Computer-Aided Diagnosis (290) Ontologies, Classifications, and Coding (359) Secondary Use of Clinical Data for Research and Surveillance (509) Machine Learning (2327) Immunology, Allergy, Rheumatology (164) Registered Report (886) Precision Medicine (195) Theme Issue: Medical Informatics and COVID-19 (126)

Published on in Vol 14 (2026)

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Preprints (earlier versions) of this paper are available at https://preprints.jmir.org/preprint/78471, first published .
Healthcare worker in blue gloves administers vaccine injection to patient.

Early Immunological Biomarkers for Personalized Treatment Selection in Severe COVID-19: Post Hoc Machine Learning Analysis of a Randomized Clinical Trial

Early Immunological Biomarkers for Personalized Treatment Selection in Severe COVID-19: Post Hoc Machine Learning Analysis of a Randomized Clinical Trial

Authors of this article:

Symeon Savvopoulos1, 2 Author Orcid Image ;   Anastasia Papadopoulou3, 4 Author Orcid Image ;   Georgios Karavalakis3 Author Orcid Image ;   Ioanna Sakellari3 Author Orcid Image ;   Grigorios Georgolopoulos3 Author Orcid Image ;   Christos Argyropoulos5, 6, 7 Author Orcid Image ;   Evangelia Yannaki3, 8 Author Orcid Image ;   Haralampos Hatzikirou1, 9 Author Orcid Image
Article Authors Cited by Tweetations Metrics

Symeon Savvopoulos   1, 2 , PhD ;   Anastasia Papadopoulou   3, 4 , PhD ;   Georgios Karavalakis   3 , MD ;   Ioanna Sakellari   3 , MD, PhD ;   Grigorios Georgolopoulos   3 , PhD ;   Christos Argyropoulos   5, 6, 7 , PhD ;   Evangelia Yannaki   3, 8 , MD, PhD ;   Haralampos Hatzikirou   1, 9 , PhD

1 Department of Mathematics, Khalifa University of Science and Technology, Abu Dhabi, United Arab Emirates

2 Faculty of Chemical Engineering and Technology, Cracow University of Technology, Cracow, Lesser Poland, Poland

3 Hematology Department-Hematopoietic Cell Transplantation Unit, Gene and Cell Therapy Center, George Papanikolaou Hospital, Thessaloniki, Greece

4 Department of Genetics, Development and Molecular Biology, School of Biology, Aristotle University of Thessaloniki, Thessaloniki, Greece

5 Department of Chemical Engineering, King Fahd University of Petroleum and Minerals, Dhahran, Saudi Arabia

6 Interdisciplinary Research Center for Refining & Advanced Chemicals, King Fahd University of Petroleum and Minerals, Dhahran, Saudi Arabia

7 Center for Integrative Petroleum Research, King Fahd University of Petroleum and Minerals, Dhahran, Saudi Arabia

8 Department of Medicine, University of Washington, Seattle, WA, United States

9 Center for Information Services and High Performance Computing, Technische Universität Dresden, Dresden, Germany

Corresponding Author:

  • Haralampos Hatzikirou, PhD
  • Center for Information Services and High Performance Computing
  • Technische Universität Dresden
  • Willers-Bau building, at Zellescher Weg 12
  • Dresden 01069
  • Germany
  • Phone: 49 351463-31943
  • Email: haralampos.hatzikirou@tu-dresden.de