Disease Progression of Hypertrophic Cardiomyopathy: Modeling Using Machine Learning

Matej Pičulin   ^{1 *} , PhD ;   Tim Smole   ^{1 *} , MSc ;   Bojan Žunkovič   ^{1 *} , PhD ;   Enja Kokalj   ^{1 *} , MSc ;   Marko Robnik-Šikonja   ^{1 *} , Prof Dr, PhD ;   Matjaž Kukar   ^{1 *} , Prof Dr, PhD ;   Dimitrios I Fotiadis   ^{2 *} , Prof Dr, PhD ;   Vasileios C Pezoulas   ^{2 *} , MSc ;   Nikolaos S Tachos   ^{2 *} , MSc ;   Fausto Barlocco   ^{3, 4 *} , PhD ;   Francesco Mazzarotto   ^{3, 4, 5 *} , PhD ;   Dejana Popović   ^{6 *} , MD, Prof Dr, PhD ;   Lars S Maier   ^{7 *} , Prof Dr, PhD ;   Lazar Velicki   ^{8, 9 *} , MD, Prof Dr, PhD ;   Iacopo Olivotto   ^{3, 4 *} , MD, Prof Dr ;   Guy A MacGowan   ^{10 *} , MD, PhD ;   Djordje G Jakovljević   ^{10, 11 *} , MD, Prof Dr, PhD ;   Nenad Filipović   ^{12 *} , Prof Dr, PhD ;   Zoran Bosnić   ^{1 *} , Prof Dr, PhD

¹ Faculty of Computer and Information Science, University of Ljubljana, Ljubljana, Slovenia

² Unit of Medical Technology and Intelligent Information Systems, Department of Materials Science and Engineering, University of Ioannina, Ioannina, Greece

³ Department of Experimental and Clinical Medicine, University of Florence, Florence, Italy

⁴ Cardiomyopathy Unit, Careggi University Hospital, University of Florence, Florence, Italy

⁵ National Heart and Lung Institute, Imperial College London, London, United Kingdom

⁶ Clinic for Cardiology, Clinical Center of Serbia, University of Belgrade, Belgrade, RS

⁷ Department of Internal Medicine II (Cardiology, Pneumology, Intensive Care Medicine), University Hospital Regensburg, Regensburg, Germany

⁸ Faculty of Medicine, University of Novi Sad, Novi Sad, RS

⁹ Institute of Cardiovascular Diseases Vojvodina, Sremska Kamenica, RS

¹⁰ Translational and Clinical Research Institute, Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne, United Kingdom

¹¹ Faculty of Health and Life Sciences, Coventry University, Coventry, United Kingdom

¹² Bioengineering Research and Development Center, Kragujevac, RS

*all authors contributed equally