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Published on in Vol 14 (2026)

Preprints (earlier versions) of this paper are available at https://preprints.jmir.org/preprint/90854, first published .
Two nurses in blue scrubs reviewing patient data on a tablet and computer.

Cloud-Based and Locally Deployed Language Models in Nursing and Health Care: An AI Act–Aligned Framework

Cloud-Based and Locally Deployed Language Models in Nursing and Health Care: An AI Act–Aligned Framework

Elena Sblendorio   1, 2 , PhD ;   Vincenzo Dentamaro   3 , PhD ;   Maddalena De Maria   4 , Prof Dr ;   Salvatore Tempesta   1 , MS ;   Elena Barile   1 , MS ;   Daniele Napolitano   5 , PhD ;   Martina Tallini   6 , MS ;   Daniela Nigrelli   1 , PhD ;   Giancarlo Cicolini   7 , Prof Dr ;   Michela Piredda   8 , Prof Dr

1 Department of Biomedicine and Prevention, University of Rome “Tor Vergata”, Rome, Lazio, Italy

2 Azienda Ospedaliero-Universitaria Consorziale Policlinico di Bari, Apulia, Italy

3 Department of Computer Science, University of Bari Aldo Moro, Bari, Apulia, Italy

4 Department of Life Health Sciences and Health Professions, Link Campus University, Rome, Lazio, Italy

5 SITRA - Direzione Scientifica - Fondazione Policlinico Gemelli IRCCS, Rome, Lazio, Italy

6 Fondazione Policlinico Universitario “A. Gemelli” IRCCS, Rome, Lazio, Italy

7 Department of Innovative Technologies in Medicine & Dentistry, “G. d'Annunzio” University of Chieti, Abruzzo, Italy

8 Department of Medicine and Surgery Research, Research Unit Nursing Science, Università Campus Bio-Medico di Roma, Rome, Lazio, Italy

Corresponding Author:

  • Michela Piredda, Prof Dr
  • Department of Medicine and Surgery Research
  • Research Unit Nursing Science, Università Campus Bio-Medico di Roma
  • Via Alvaro del Portillo, 21
  • Rome, Lazio 00128
  • Italy
  • Phone: 39 06225418833
  • Email: m.piredda@unicampus.it