A Biomedical Knowledge Graph System to Propose Mechanistic Hypotheses for Real-World Environmental Health Observations: Cohort Study and Informatics Application
A Biomedical Knowledge Graph System to Propose Mechanistic Hypotheses for Real-World Environmental Health Observations: Cohort Study and Informatics Application
Karamarie Fecho
1, 2
, PhD ;
Chris Bizon
1
, PhD ;
Frederick Miller
3
, MD, PhD ;
Shepherd Schurman
3
, MD ;
Charles Schmitt
3
, PhD ;
William Xue
3
, BSc ;
Kenneth Morton
4
, PhD ;
Patrick Wang
4
, PhD ;
Alexander Tropsha
1, 5
, PhD
1
Renaissance Computing Institute, University of North Carolina at Chapel Hill, Chapel Hill, NC, United States
2
Copperline Professional Solutions, Pittsboro, NC, United States
3
National Institute of Environmental Health Sciences, Durham, NC, United States
4
CoVar Applied Technologies, Durham, NC, United States
5
Eshelman School of Pharmacy, University of North Carolina at Chapel Hill, Chapel Hill, NC, United States