Published on in Vol 14 (2026)

Preprints (earlier versions) of this paper are available at https://preprints.jmir.org/preprint/78964, first published .
Prediction of First and Multiple Antiretroviral Therapy Interruptions in People Living With HIV: Comparative Survival Analysis Using Cox and Explainable Machine Learning Models

Prediction of First and Multiple Antiretroviral Therapy Interruptions in People Living With HIV: Comparative Survival Analysis Using Cox and Explainable Machine Learning Models

Prediction of First and Multiple Antiretroviral Therapy Interruptions in People Living With HIV: Comparative Survival Analysis Using Cox and Explainable Machine Learning Models

Donald Salami   1 , PhD ;   Emily Koech   2 , MD ;   Janet M Turan   3 , PhD ;   Kristen A Stafford   1 , PhD ;   Lilly Muthoni Nyagah   4 , PhD ;   Stephen Ohakanu   1 , BEng ;   Anthony K Ngugi   5 , PhD ;   Manhattan Charurat   1 , Prof Dr

1 Center for International Health, Education and Biosecurity, Institute of Human Virology, School of Medicine, University of Maryland, Baltimore, MD, United States

2 Center for International Health, Education, and Biosecurity, Kenya, Nairobi, Kenya

3 Department of Health Policy and Organization, School of Public Health, The University of Alabama, Birmingham, AL, United States

4 Department of Strategic Information, Ministry of Health’s National AIDS and STI Control Program Kenya, Nairobi, Kenya

5 Department of Population Health, Aga Khan University Nairobi, Nairobi, Kenya

Corresponding Author:

  • Donald Salami, PhD
  • Center for International Health, Education and Biosecurity, Institute of Human Virology
  • School of Medicine, University of Maryland
  • 725 W Lombard St
  • Baltimore, MD 21201
  • United States
  • Phone: 1 410-706-8614
  • Email: dsalami@ihv.umaryland.edu