Published on in Vol 14 (2026)

Preprints (earlier versions) of this paper are available at https://preprints.jmir.org/preprint/78519, first published .
Knowledge-Guided Explainable Recommendation Tool for Cancer Risk Prediction Models Using Retrieval-Augmented Large Language Models: Development and Validation Study

Knowledge-Guided Explainable Recommendation Tool for Cancer Risk Prediction Models Using Retrieval-Augmented Large Language Models: Development and Validation Study

Knowledge-Guided Explainable Recommendation Tool for Cancer Risk Prediction Models Using Retrieval-Augmented Large Language Models: Development and Validation Study

Shumin Ren   1, 2 * , PhD ;   Xin Zheng   1 * , MSc ;   Jing Zhao   1 , MSc ;   Jiale Du   1 , MSc ;   Yuxin Zhang   1 , MSc ;   Cheng Bi   1 , MSc ;   Jie Song   1 , MSc ;   Jinyi Zhang   2 , MSc ;   Hongmei Lang   2 , MD ;   Fan Zhang   3 , MD ;   Bairong Shen   1 , Prof Dr

1 Institutes for Systems Genetics, West China Hospital of Sichuan University, Chengdu, Sichuan, China

2 West China School of Medicine, Sichuan University, Sichuan University affiliated Chengdu Second People's Hospital, Chengdu Second People's Hospital, Chengdu, Sichuan, China

3 Health Management Center, General Practice Medical Center, West China Hospital, Sichuan University, Chengdu, Sichuan, China

*these authors contributed equally

Corresponding Author:

  • Bairong Shen, Prof Dr
  • Institutes for Systems Genetics
  • West China Hospital of Sichuan University
  • Frontiers Science Center for Disease-related Molecular Network
  • Chengdu, Sichuan 610041
  • China
  • Phone: 86 15995854635
  • Email: bairong.shen@scu.edu.cn