A Machine Learning Approach to Predicting Mortality Risk in Chemotherapy-Treated Lung Cancer: Machine Learning Model Development and Validation

Jianjun Zou   ^{1, 2, 3 *} , MD ;   Jinyi Huang   ^{4 *} , MD ;   Katie Lu   ^{5 *} , BD ;   Ao Lin   ^{4, 6, 7} , MD, PhD ;   Chen Xie   ⁴ , MD ;   Jinrong Zhang   ⁴ , MD ;   Boqi Rao   ^{4, 6, 8} , MD, PhD ;   Zhi Li   ⁴ , MD ;   Dongming Xie   ⁴ , MD ;   Ling Lu   ⁴ , MD ;   Feng Luo   ⁴ , BD ;   Jinbin Chen   ⁹ , MD, PhD ;   Lei Yang   ^{4, 10, 11} , MD, PhD ;   Fuman Qiu   ⁴ , MD, PhD ;   Xin Zhang   ^{6, 7, 12} , MD, PhD ;   Yibin Deng   ¹³ , MD, PhD ;   Jiachun Lu   ^{4, 10, 11} , MD, PhD

¹ Institute of Tuberculosis, Guangzhou Medical University, Guangzhou, Guangdong, China

² Guangzhou Key Laboratory of Tuberculosis Research, Guangzhou Chest Hospital, Guangzhou, Guangdong, China

³ Department of General Medicine, Guangzhou Chest Hospital, Guangzhou, Guangdong, China

⁴ School of Public Health, Guangzhou Medical University, Guangzhou, Guangdong, China

⁵ School of Medicine, University of Arizona, Tucson, AZ, United States

⁶ State Key Laboratory of Respiratory Disease, Guangzhou Medical University, Guangzhou, Guangdong, China

⁷ Department of Thoracic Surgery, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou, Guangdong, China

⁸ Emergency Department, The Second Affiliated Hospital of Guangzhou Medical University, Guangzhou, China

⁹ KingMed School of Laboratory Medicine, Guangzhou Medical University, Guangzhou, China

¹⁰ The Key Laboratory of Advanced Interdisciplinary Studies, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou, Guangdong, China

¹¹ The Institute for Chemical Carcinogenesis, Guangzhou Medical University, Guangzhou, Guangdong, China

¹² Guangzhou Institute of Respiratory Health, Guangzhou Medical University, Guangzhou, China

¹³ Centre for Medical Laboratory Science, The Affiliated Hospital of Youjiang Medical University for Nationalities, Baise, China

*these authors contributed equally