Critical Predictors for the Early Detection of Conversion From Unipolar Major Depressive Disorder to Bipolar Disorder: Nationwide Population-Based Retrospective Cohort Study

Ya-Han Hu   ^{1, 2, 3} , PhD ;   Kuanchin Chen   ⁴ , DBA ;   I-Chiu Chang   ⁵ , PhD ;   Cheng-Che Shen   ^{5, 6, 7} , MD, PhD

¹ Center for Innovative Research on Aging Society, National Chung Cheng University, Chiayi County, Taiwan

² MOST AI Biomedical Research Center, National Cheng Kung University, Tainan City, Taiwan

³ Department of Information Management, National Central University, Taoyuan City, Taiwan

⁴ Department of Business Information Systems, Western Michigan University, Kalamazoo, MI, United States

⁵ Department of Information Management and Institute of Healthcare Information Management, National Chung Cheng University, Chiayi County, Taiwan

⁶ Department of Psychiatry, Chiayi Branch, Taichung Veterans General Hospital, Chiayi City, Taiwan

⁷ School of Medicine, National Yang-Ming University, Taipei, Taiwan