Adverse Drug Events Detection, Pharmacovigilance and Surveillance

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Articles published in 2026 in this theme: 43 (scroll down to load remaining articles)

2026

Doctor discusses results with a concerned woman during a gynecological exam.

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Safety and Effectiveness of Motherwort Injection for Hemostasis and Menstrual Regulation: Protocol for a Prospective, Observational, Multicenter Real-World Study

Sicun Wang, Muzhi Li, Shuang Guan, Jun Liu, Haixia Dang, Zhong Wang, Yanan Yu

JMIR Res Protoc 2026 (Nov 11); 15:e103997

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Smartphone screen showing AI-driven research for Huntingtin's disease drug discovery

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Conversational Multi-Agentic Network-Driven Disease Module Identification and Drug Repurposing Prediction With ChatDRex: Platform Development Study

Simon Süwer, Kester Bagemihl, Sylvie Baier, Lucia Dicunta, Markus List, Jan Baumbach, Fernando Miguel Delgado-Chaves, Andreas Maier

JMIR AI 2026 (Nov 03); 5:e93862

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Two healthcare professionals review chart with a small robot in a hospital setting.

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Machine Learning–Based Detection of Prophylactic Indication Mentions for Stress-Related Mucosal Disease in Chinese Clinical Progress Notes: Text Classification Study

Wei Jiang, Shuo Wang, Haonan Liang, Luyao Xu, Jie Hu

JMIR Med Inform 2026 (Nov 02); 14:e103192

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Hand squeezing white cream from tube onto fingertip

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Topical Esomeprazole for the Prevention and Treatment of Radiation Dermatitis in Patients With Head and Neck Cancer: Protocol for a Phase 2 Randomized Controlled Trial

Aaron Cheng, Pavela Bambekova, Yohannes T Ghebre, Mark D Bonnen, Timothy Wagner, Sandra Osswald, Carol Jenkins, Pia Roperes, Shraddha Dalwadi

JMIR Res Protoc 2026 (Nov 02); 15:e91035

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Tablet screen displays "Medication" with icons of pills and bottles.

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Safety and Performance Evaluation of a Clinical Decision Support System for Imatinib Therapeutic Drug Monitoring: In Silico Study

Yuan James Pétermann, Roberto Rigamonti, Paul Thoueille, Junrui Chen, Lavinia Alberi, Alexandra Simon, François Veuve, Eva Choong, Bruno Da Rocha Carvalho, Sandro Carrara, François R Girardin, Thierry Buclin, Chantal Csajka, Yann Thoma, Monia Guidi

JMIR Med Inform 2026 (Oct 21); 14:e93304

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3D scan of child's skeletal system and internal organs with IV drip

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[177Lu]Lu-DOTATATE Molecular Radiotherapy During Induction Chemotherapy for First-Line Stage 4 High-Risk Neuroblastoma in South African Children: Protocol for a Phase 1 Randomized Controlled Trial (LuDO-SA Trial)

Jaques van Heerden, Mariana Kruger, Kershinee Reddy, Anel van Zyl, James Warwick, Celeste Burger, Tumelo Moalosi, Christoffel van Reenen, Alan Davidson, Khanyisile Hlongwa, Daniella Violante, Nanette Bruwer, Gita Naidu, Biance Rowe, Lizette Louw, Bronwin van Wyk, Mariza Vorster, Thokozani Mkhize, Anita Brink

JMIR Res Protoc 2026 (Sep 30); 15:e93547

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Transformer-based language model for EHRs, identifying misspelled medication names.

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Detecting Misspelled Drug Names Using Transformer-Based Language Models: Model Development and External Validation

Jiayu Lu, Kevin W McConeghy, Andrew R Zullo, Jinying Chen

JMIR Med Inform 2026 (Sep 29); 14:e91151

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Woman's hands pouring green and blue capsules from a bottle into her palm

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Harnessing Data Warehousing for Precision in Off-Label Prescription Detection in Psychiatry (PSYHAMM): Retrospective Proof-of-Concept Evaluation Study

Emmanuel Chevallier, Catherine Letord, Jean Charlet, Marie-Odile Krebs, Emmanuelle Advenier-Iakovlev, Stefan J Darmoni, Julien Grosjean, Romain Leguillon

JMIR Form Res 2026 (Sep 29); 10:e71516

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Laptop screen displaying a medical record form with fields for personal information.

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Natural Language Processing Identification of Nonprescribed Fentanyl Use in Electronic Health Records: Algorithm Development and Validation Study

Joshua Trujeque, Joseph A Simonetti, Isai Ortiz, Nicholas E Ingraham, Nathan Mesfin, Jeremy Yeung, Rui Zhang, Lisa A Brenner, R Adams Dudley

J Med Internet Res 2026 (Sep 09); 28:e97485

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White pill bottle tipped over with green and white capsules scattered on a gray surface.

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Examining Increased Ritalin and Adderall Use Among Low-Income People Who Use Drugs: Mixed Methods Study

Ian David Aronson, Robert Quiles, Anthony Cramer, Chunki Fong, Alex S Bennett

JMIR Form Res 2026 (Sep 01); 10:e99947

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Mother gives child medicine capsules while she lies in bed

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Global Prevalence and Associated Factors of Medication Errors in Hospitalized Pediatric Patients: Systematic Review and Meta-Analysis

Xiuwen Chen, Yuan Meng, Xueyi Wei, Ailian Li, Jiqun He, Liqing Yue

JMIR Pediatr Parent 2026 (Aug 27); 9:e100070

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Medical supplies: stethoscope, syringe, thermometer, and pills on a wooden desk.

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User Experiences of Electronic Controlled Substance Surveillance Among Health Care Professionals in a Large Academic Hospital: Cross-Sectional Survey

Annika Häkkinen, Tinja Lääveri, Johanna Viitanen, Kaisa Savolainen, Mia Sivén, Hanna M Tolonen

J Med Internet Res 2026 (Aug 26); 28:e94815

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Close-up of an arm with an IV drip inserted into the vein, on a white medical sheet.

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Efficacy of Corticosteroid Therapy on Neurological Outcomes in Near-Hanging Patients With Altered Sensorium: Protocol for a Multicenter, Double-Blinded, Placebo-Controlled, Randomized Trial (CHANGING Trial)

Ramadoss Ramu, Dineshbabu Sekar, Aswin K, Ashish Behera, Manu Ayyan, Harichandra Kumar KT, Kavitha B, Mohan Kumar Hanumanthappa, Sree Naga Sowndary Rajendran

JMIR Res Protoc 2026 (Aug 25); 15:e100623

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Hand holding various pills and capsules, including orange and white capsules.

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Objective Assessment of Medication Adherence Through Automated Pill Detection Using a Computer Vision Framework: Development and Evaluation Study

Haozhe Liu, Yaguang Zheng, Bei Wu, Yu Gan

JMIR AI 2026 (Aug 18); 5:e92528

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Boulder app on phone: Pick up Suboxone, visit clinician, get help, monthly check-in.

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Retention in Telehealth-Delivered Buprenorphine Treatment for Opioid Use Disorder: Multistate Retrospective Cohort Study

Laura B Monico, Elizabeth A Bambury, Jennifer K Foreman, Melody Avila, Stephen A Martin

J Med Internet Res 2026 (Aug 14); 28:e100527

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Doctor reviewing ADE Identification software on computer screen

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Intelligent Framework for Adverse Drug Event Identification Using Large Language Models and Retrieval-Augmented Generation: Development and Evaluation Study

Junlong Ma, Xuehong Wu, Zeying Feng, Yun Kuang, Zhendong Ding, Min Li, Guoping Yang

J Med Internet Res 2026 (Aug 10); 28:e84086

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Pharmacist discusses medication with a patient in a pharmacy aisle.

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Using Natural Language Processing to Identify Adverse Drug Events Characterized by Medication Replacement in Primary Care Electronic Medical Records: Algorithm and Validation Study

Alan Katz, Abhishek Dhankar, Gillian Fransoo, Diane Gordon Pappas, Amani F Hamad, Christine Leong, Alexander Singer

J Med Internet Res 2026 (Aug 10); 28:e86467

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Mobile app displaying drug compatibility network graph with Dopamine, Dobutamine, Phentolamine, Amiodarone

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A Network Visualization Query System for Multidrug Compatibility Based on a WeChat Mini Program: Preliminary Usability and Efficiency Evaluation

Jianhui Yang, Xiaoqing Huang, Shurong Wu, Yuanyuan Zhang, Xiaofang Zhuang, Yilun Dong, Biru Li, Zhida Hong

JMIR Form Res 2026 (Jul 21); 10:e86583

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Man explaining AI drug safety data on a large screen to a woman in an office

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AI for Causality Assessment in Pharmacovigilance: Protocol for a Scoping Review

Miki Ohta, Miki Ota, Mikihiko Ohta

JMIR Res Protoc 2026 (Jul 16); 15:e101691

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Pregnant woman and time-concentration curve showing drug levels in blood samples

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Single-Dose Longitudinal Pharmacokinetic Evaluation of Doravirine in Pregnant Women Living With HIV: Protocol for a Phase 1 Study

Amanda Poliseno, Lisa Rahangdale, Cynthia Gay, Emma Trawick Roberts, Angela Kashuba

JMIR Res Protoc 2026 (Jul 10); 15:e89990

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