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This paper is in the following e-collection/theme issue:

Viewpoints on and Experiences with Digital Technologies in Health (298) Ethics, Privacy, and Legal Issues (829) Theoretical Frameworks and Concepts (574) Precision Medicine (448) Prescribable Digital Interventions (Digital Therapeutics) (83) Responsible Health AI (243)

Published on in Vol 14 (2026)

Preprints (earlier versions) of this paper are available at https://preprints.jmir.org/preprint/78202, first published .
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SAFE_DTx: Safety-First Framework for AI-Driven Personalization in Digital Therapeutics

SAFE_DTx: Safety-First Framework for AI-Driven Personalization in Digital Therapeutics

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