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Skip search results from other journals and go to results- 2 JMIR Medical Informatics
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As noted earlier, dementia is not a monolithic disease; therefore, both cognitive and functional abilities need to be measured to accurately assess its severity and progression. Standardized cognitive tests can provide objective measures of cognitive functioning in different domains such as memory and executive function.
JMIR Aging 2025;8:e65292
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However, data-driven clinical decision support tools with the ability to generate transition probabilities and progression paths can allow the development of effective intervention strategies at a cohort level, leading to better treatment outcomes. For this purpose, researchers have proposed and developed various quantitative disease progression models based on mathematical functions to understand the progression patterns of complex chronic diseases [6].
JMIR Med Inform 2024;12:e59392
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Given that one of the key stated purposes of the OPD pathway is to “manage breakdown and failure...to support future progression” [30], it is important to understand why some offenders are not progressing to learn how pathway plans can adapt. The OPD pathway is informed from the “What Works?” literature [31], the risk needs responsivity (RNR) principles [32] and the Good Lives Model [29].
JMIRx Med 2021;2(4):e27907
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It is challenging to define this transition from RRMS to SPMS because of the lack of a clear consensus on the diagnostic criteria and the absence of reliable biomarkers of disease progression [4]. This delay in SPMS diagnosis may affect long-term prognosis and treatment decision-making [5]. Previous research has confirmed an unmet need for a tool to facilitate systematic assessment of the early signs of progression to SPMS in routine clinical practice [6].
J Med Internet Res 2021;23(10):e29558
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A disease progression and transmission model is used to estimate the size and composition of the COVID-19 period prevalence by integrating the results of previous seroprevalence surveys with primary provincial observed data of health events related to COVID-19 and its sequelae, including COVID-19–related deaths. From these estimates, we derive the proportion of the infected population that remained undiagnosed during this period.
JMIR Public Health Surveill 2021;7(9):e26409
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Reference 15: A predictive model for distinguishing radiation necrosis from tumour progression after Reference 16: Shape features of the lesion habitat to differentiate brain tumor progression from pseudoprogression Reference 27: Severity assessment and progression prediction of COVID-19 patients based on the LesionEncoderprogression
JMIR Med Inform 2020;8(11):e19805
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Studies have reported that the onset of progression is early, with discrete and identifiable signs seen even at a disability status score of two or lower [2]. In many RRMS patients, silent accrual of disability progression independent of relapse activity has also been observed [15].
In previous research, physicians confirmed an unmet need for a tool that could be used in routine clinical practice to raise awareness and facilitate the systematic assessment of early signs of progression to SPMS.
J Med Internet Res 2020;22(2):e16932
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