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Skip search results from other journals and go to results- 2 Journal of Medical Internet Research
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Vancomycin is a first-line treatment for methicillin-resistant Staphylococcus aureus (MRSA) infections [1,2]. Due to its narrow therapeutic index, therapeutic drug monitoring (TDM) of vancomycin is essential to achieving effective outcomes while minimizing side effects such as nephrotoxicity and ototoxicity [3-6].
J Med Internet Res 2025;27:e63983
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Patients with critical illnesses (>18 years) with intravenous vancomycin treatment history and who had at least 1 test for vancomycin TDM were eligible for this study. Vancomycin TDM was investigated for trough-level information. If the TDM was checked multiple times, only the first TDM value was selected. However, in patients with normal renal function, if the interval between stopping vancomycin and readministering it was 2 weeks or more, it was considered an independent TDM value and used for analyses.
JMIR Form Res 2024;8:e45202
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Therapeutic drug monitoring (TDM) for vancomycin is a recommended practice to balance efficacy and the risk of AKI. This involves the monitoring of the systemic serum vancomycin concentration (VCs) over time after drug administration and subsequent adjustments of vancomycin dosage as necessary.
Vancomycin is eliminated from the systemic circulation primarily through glomerular filtration in the kidneys.
JMIR Med Inform 2022;10(1):e29458
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Vancomycin is a commonly used antibiotic for treatment of MRSA infections [19], but there are problems associated with its use. Those include the requirement for a loading dose (initial higher single dose) in serious infections, side effects when administered too rapidly, and the need to monitor vancomycin plasma levels [20]. As part of our antimicrobial stewardship program [21], local quality improvement activities identified gaps in competence around clinical use of vancomycin.
J Med Internet Res 2017;19(3):e93
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