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Efficacy of eHealth Interventions for Hemodialysis Patients: Systematic Review and Meta-Analysis

Efficacy of eHealth Interventions for Hemodialysis Patients: Systematic Review and Meta-Analysis

Hemodialysis (HD), the primary modality of renal replacement therapy for advanced kidney failures, plays a crucial role in mitigating the otherwise inevitable progressive decline in kidney function [4]. As of 2020, it is estimated that 88.07% of patients with ESRD in the United States were undergoing HD, compared with 46% to 98% of patients in Europe [5,6].

Xu-Hua Zhou, Hui Chen, Weiwei Yang, Li Wang, Lin Chen, Ying Zhu, Yingjun Zhang, Mei Shi, Qin Zhang

J Med Internet Res 2025;27:e67246

Effectiveness of Virtual Reality Training in Improving Outcomes for Dialysis Patients: Systematic Review and Meta-Analysis

Effectiveness of Virtual Reality Training in Improving Outcomes for Dialysis Patients: Systematic Review and Meta-Analysis

Dialysis, encompassing both hemodialysis (HD) and peritoneal dialysis (PD), serves as a common therapeutic approach for ESRD, substituting renal filtration function albeit necessitating frequent hospital visits, significantly impacting patients’ lives. Prolonged dialysis treatment often precipitates complications such as anemia, muscle wasting, skeletal disorders, and cardiovascular ailments.

Xin Kang, Yiping Zhang, Chaonan Sun, Jiaxin Zhang, Zhe Che, Jinhui Zang, Rongzhi Zhang

J Med Internet Res 2025;27:e58384

Participation in eHealth Communication Interventions Among Patients Undergoing Hemodialysis: Scoping Review

Participation in eHealth Communication Interventions Among Patients Undergoing Hemodialysis: Scoping Review

Despite substantial improvements in hemodialysis delivery and outcomes over the last decade, patients undergoing hemodialysis continue to have negative experiences [1]. Particularly, patients undergoing hemodialysis still experience poor quality of life (QOL); their symptoms remain prevalent; and their financial burden, morbidity, and mortality remain unacceptably high [2].

Anne Deinboll, Cathrine Fredriksen Moe, Mette Spliid Ludvigsen

J Med Internet Res 2024;26:e51900

Efficacy of a Web-Based Home Blood Pressure Monitoring Program in Improving Predialysis Blood Pressure Control Among Patients Undergoing Hemodialysis: Randomized Controlled Trial

Efficacy of a Web-Based Home Blood Pressure Monitoring Program in Improving Predialysis Blood Pressure Control Among Patients Undergoing Hemodialysis: Randomized Controlled Trial

Hemodialysis has become the predominant renal replacement therapy for individuals with end-stage renal disease, the final stage of chronic kidney disease. The prevalence of patients receiving hemodialysis has surged alongside the increasing incidence of end-stage renal disease cases. Globally, the number of patients requiring renal replacement therapy is expected to reach 5.4 million by 2030, with nearly 89% of them undergoing hemodialysis [1].

Tingting Chen, Wenbo Zhao, Qianqian Pei, Yanru Chen, Jinmei Yin, Min Zhang, Cheng Wang, Jing Zheng

JMIR Mhealth Uhealth 2024;12:e53355

Duration of Protection From Pneumonia After Pneumococcal Vaccination in Hemodialysis Patients (DOPPIO): Protocol for a Prospective Multicenter Study

Duration of Protection From Pneumonia After Pneumococcal Vaccination in Hemodialysis Patients (DOPPIO): Protocol for a Prospective Multicenter Study

While a recent meta-analysis demonstrated the efficacy of pneumococcal vaccination in reducing pneumonia in the overall adult target population [8], randomized or well-designed prospective studies in a hemodialysis population are still lacking. Prior immunological studies in hemodialysis patients have been limited by low patient numbers and mixed populations (CKD 1-4, hemodialysis, and renal transplant recipients) [9].

Sibylle Mellinghoff, Gero von Gersdorff, Caroline Bruns, Kerstin Albus, Vassiliki Dimitriou, Angela Steinbach, Mathias Schaller, Jörg Janne Vehreschild, Oliver A Cornely, Blasius Janusch Liss

JMIR Res Protoc 2023;12:e45712

Positive Psychological Intervention Delivered Using Virtual Reality in Patients on Hemodialysis With Comorbid Depression: Protocol and Design for the Joviality Randomized Controlled Trial

Positive Psychological Intervention Delivered Using Virtual Reality in Patients on Hemodialysis With Comorbid Depression: Protocol and Design for the Joviality Randomized Controlled Trial

End-stage kidney disease (ESKD) requiring hemodialysis is a taxing condition that requires difficult self-care practices (eg, multiple weekly treatment center visits) [1]. Depression is the most pervasive psychological issue in this patient population and presents a substantial added burden: one-third of individuals on hemodialysis in the United States report compromised emotional well-being [2].

Rosalba Hernandez, Ken Wilund, Killivalavan Solai, David Tamayo, Drew Fast, Prasakthi Venkatesan, James P Lash, Claudia M Lora, Lizet Martinez, Geovana Martin Alemañy, Angela Martinez, Soonhyung Kwon, Dana Romero, Matthew H E M Browning, Judith T Moskowitz

JMIR Res Protoc 2023;12:e45100

Physician Compliance With a Computerized Clinical Decision Support System for Anemia Management of Patients With End-stage Kidney Disease on Hemodialysis: Retrospective Electronic Health Record Observational Study

Physician Compliance With a Computerized Clinical Decision Support System for Anemia Management of Patients With End-stage Kidney Disease on Hemodialysis: Retrospective Electronic Health Record Observational Study

To address this knowledge gap, we conducted this study to evaluate the impact of physician compliance with CDSSs for anemia management in patients with ESKD undergoing hemodialysis. We extracted the electronic health records of patients with ESKD undergoing hemodialysis at the Far Eastern Memorial Hospital (FEMH) medical center from 2016 to 2020. Patients with ESKD were defined as those on stable hemodialysis for >3 months.

Ju-Yeh Yang, Kai-Hsiang Shu, Yu-Sen Peng, Shih-Ping Hsu, Yen-Ling Chiu, Mei-Fen Pai, Hon-Yen Wu, Wan-Chuan Tsai, Kuei-Ting Tung, Raymond N Kuo

JMIR Form Res 2023;7:e44373

Implementing a Health Utility Assessment Platform to Acquire Health Utilities in a Hemodialysis Outpatient Setting: Feasibility Study

Implementing a Health Utility Assessment Platform to Acquire Health Utilities in a Hemodialysis Outpatient Setting: Feasibility Study

We worked with physicians in the Division of Nephrology and Hypertension to help recruit patients with chronic hemodialysis receiving treatment at any of the 4 outpatient dialysis centers in the greater Cincinnati metropolitan area managed by Dialysis Center Inc (DCI) [17]. Inclusion criteria were a diagnosis of ESKD, receiving intermittent facility hemodialysis at the designated outpatient center (DCI), and the ability to understand the English language.

Adeboye A Adejare, Heather J Duncan, R Geoffrey Motz, Silvi Shah, Charuhas V Thakar, Mark H Eckman

JMIR Form Res 2022;6(7):e33562

Hemodialysis Record Sharing: Solution for Work Burden Reduction and Disaster Preparedness

Hemodialysis Record Sharing: Solution for Work Burden Reduction and Disaster Preparedness

Patients undergoing hemodialysis (HD) require collaborative team care, not only because their renal function is poor but also because they are vulnerable to various comorbidities [1,2]. Since an increase in the number of comorbidities makes care for patients more complex, multiple medical facilities may need to share patient information, and diverse specialist expertise may be required for patient management.

Keisuke Ido, Mariko Miyazaki, Masaharu Nakayama

JMIR Form Res 2022;6(7):e32925

Machine Learning Analysis of Time-Dependent Features for Predicting Adverse Events During Hemodialysis Therapy: Model Development and Validation Study

Machine Learning Analysis of Time-Dependent Features for Predicting Adverse Events During Hemodialysis Therapy: Model Development and Validation Study

Hemodialysis (HD) therapy has a substantial role in critical care management [1]. Due to oliguria or even anuria, most patients with renal failure require fluid removal during HD therapy to maintain an euvolemic status. The volume-dependent component of hypertension may be corrected by fluid removal, but the ultrafiltration process exposes HD patients to the risks of hemodynamic instability, which may lead to fatal consequences such as cardiac arrest [2].

Yi-Shiuan Liu, Chih-Yu Yang, Ping-Fang Chiu, Hui-Chu Lin, Chung-Chuan Lo, Alan Szu-Han Lai, Chia-Chu Chang, Oscar Kuang-Sheng Lee

J Med Internet Res 2021;23(9):e27098