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The enzymatic system of Cytochrome P450 (CYP450) is a group of enzymes involved in the metabolism of drugs present in the liver. CYP450 functions by oxidizing molecules through various chemical reactions. These reactions give rise to active or inactive metabolites, and sometimes among these, to toxic metabolites [1].
JMIR Med Inform 2024;12:e57705
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Cytochrome P450 1B1 Overexpression in Cervical Cancers: Cross-sectional Study
Several metabolic enzymes, particularly members of the cytochrome P450 (CYP) superfamily, are being investigated for their potential role in tumor malignancy [6-8]. Of recent interest is a novel member of the CYP1 gene family, CYP1 B1, which is an extrahepatic enzyme that is engaged in the metabolism of several endogenous and xenobiotic compounds [9]. CYP1 B1 has been implicated in the oxidation of steroids, particularly estrogen and melatonin.
Interact J Med Res 2021;10(4):e31150
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