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Subphenotyping of Mexican Patients With COVID-19 at Preadmission To Anticipate Severity Stratification: Age-Sex Unbiased Meta-Clustering Technique

Subphenotyping of Mexican Patients With COVID-19 at Preadmission To Anticipate Severity Stratification: Age-Sex Unbiased Meta-Clustering Technique

Recognizing different COVID-19 subphenotypes—the division of populations of patients into more meaningful subgroups driven by clinical features [6,7]—and their severity characterization may assist clinicians during the clinical course, research efforts, and the surveillance system.

Lexin Zhou, Nekane Romero-García, Juan Martínez-Miranda, J Alberto Conejero, Juan M García-Gómez, Carlos Sáez

JMIR Public Health Surveill 2022;8(3):e30032

Using Unsupervised Machine Learning to Identify Age- and Sex-Independent Severity Subgroups Among Patients with COVID-19: Observational Longitudinal Study

Using Unsupervised Machine Learning to Identify Age- and Sex-Independent Severity Subgroups Among Patients with COVID-19: Observational Longitudinal Study

For a clearer characterization of the clusters, Figure 1 shows a radar chart with the variables (ie, hospital stay, outcome measures, and laboratory tests) that showed statistically significant differences among the clusters and a medium or high effect size (η2>0.06) [36]. A web-based cluster assignment tool, based on the results reported here, can be found online [37].

Julián Benito-León, Mª Dolores del Castillo, Alberto Estirado, Ritwik Ghosh, Souvik Dubey, J Ignacio Serrano

J Med Internet Res 2021;23(5):e25988