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Applying Natural Language Processing Techniques to Map Trends in Insomnia Treatment Terms on the r/Insomnia Subreddit: Infodemiology Study

Applying Natural Language Processing Techniques to Map Trends in Insomnia Treatment Terms on the r/Insomnia Subreddit: Infodemiology Study

Terms related to benzodiazepines overall showed a general increase in frequency over time (Figure 2), with a gradual increase from 2013 to 2016, a gradual decrease from 2016 to 2019, and a subsequent increase from 2020 to 2022.

Jack A Cummins, Daniel J Gottlieb, Tamar Sofer, Danielle A Wallace

J Med Internet Res 2025;27:e58902

Barriers to, and Facilitators of, Checking Drugs for Adulterants in the Era of Fentanyl and Xylazine: Qualitative Study

Barriers to, and Facilitators of, Checking Drugs for Adulterants in the Era of Fentanyl and Xylazine: Qualitative Study

The majority of these overdose fatalities involved the synthetic opioid fentanyl (which is often illicitly manufactured and can be hundreds of times more powerful than morphine [6]), as well as other adulterants including xylazine [7] and benzodiazepines [8]. All can be present in a drug without people’s knowledge.

Ian David Aronson, Mary-Andrée Ardouin-Guerrier, Juan Esteban Baus, Alex S Bennett

JMIR Form Res 2024;8:e56755

Implementing Blended Care to Discontinue Benzodiazepine Receptor Agonist Use for Insomnia: Process Evaluation of a Pragmatic Cluster Randomized Controlled Trial

Implementing Blended Care to Discontinue Benzodiazepine Receptor Agonist Use for Insomnia: Process Evaluation of a Pragmatic Cluster Randomized Controlled Trial

Finally, the importance of support and encouragement cannot be underestimated, as it was also associated with successful discontinuation in the EMPOWER study, in which a deprescribing brochure on benzodiazepines was mailed to older adult patients [41]. Fifth, blended care was implemented pragmatically, that is, without a protocol.

Kristien Coteur, Marc Van Nuland, Birgitte Schoenmakers, Sibyl Anthierens, Kris Van den Broeck

JMIR Form Res 2023;7:e43738

Overcoming Decisional Gaps in High-Risk Prescribing by Junior Physicians Using Simulation-Based Training: Protocol for a Randomized Controlled Trial

Overcoming Decisional Gaps in High-Risk Prescribing by Junior Physicians Using Simulation-Based Training: Protocol for a Randomized Controlled Trial

For example, the use of medications such as antipsychotics, benzodiazepines, and sedative hypnotic “Z-drugs,” to manage delirium and agitation for hospitalized patients remains highly prevalent despite considerable risks associated with their use and guidelines that recommend their avoidance in older adults [12-15]. In this context, there are numerous factors that are stressful for physicians which promote System 1 thinking.

Julie C Lauffenburger, Matthew F DiFrancesco, Renee A Barlev, Ted Robertson, Erin Kim, Maxwell D Coll, Nancy Haff, Constance P Fontanet, Kaitlin Hanken, Rebecca Oran, Jerry Avorn, Niteesh K Choudhry

JMIR Res Protoc 2022;11(4):e31464

Analysis of Benzodiazepine Prescription Practices in Elderly Appalachians with Dementia via the Appalachian Informatics Platform: Longitudinal Study

Analysis of Benzodiazepine Prescription Practices in Elderly Appalachians with Dementia via the Appalachian Informatics Platform: Longitudinal Study

Associated contributory factors to dementia, such as excessive prescription of medications (eg, benzodiazepines [BZD]), poor rates of health screening, and high illiteracy, have also been found to be highly prevalent in West Virginia and the rest of the Appalachia [7-9]. Thus, caring for patients with dementia is challenging, especially in Appalachia, because of the complexities that arise due to the increased burden of aforementioned comorbidities and contributory factors [10].

Niharika Bhardwaj, Alfred A Cecchetti, Usha Murughiyan, Shirley Neitch

JMIR Med Inform 2020;8(8):e18389

Effectiveness of Internet-Delivered Computerized Cognitive Behavioral Therapy for Patients With Insomnia Who Remain Symptomatic Following Pharmacotherapy: Randomized Controlled Exploratory Trial

Effectiveness of Internet-Delivered Computerized Cognitive Behavioral Therapy for Patients With Insomnia Who Remain Symptomatic Following Pharmacotherapy: Randomized Controlled Exploratory Trial

Remaining symptomatic was defined herein as having insomnia that is at least moderate in severity, based on a Pittsburgh Sleep Quality Index (PSQI) score of greater than 5.5 [15,17,18] after the use of hypnotics including nonbenzodiazepines, benzodiazepines, melatonin receptor agonists, orexin receptor antagonists, and antidepressants. Each participant’s treatment history was confirmed by their prescribing clinician and by chart review.

Daisuke Sato, Naoki Yoshinaga, Eiichi Nagai, Kazue Nagai, Eiji Shimizu

J Med Internet Res 2019;21(4):e12686

An Internet-Based Method for Extracting Nursing Home Resident Sedative Medication Data From Pharmacy Packing Systems: Descriptive Evaluation

An Internet-Based Method for Extracting Nursing Home Resident Sedative Medication Data From Pharmacy Packing Systems: Descriptive Evaluation

Additionally, a measure of sedative load was calculated for each resident: the average daily dose for each medication was determined and compared with the World Health Organization’s Defined Daily Dose (DDD) values [40]; to enable reporting at a nursing home level, daily doses were converted to an equivalent strength of diazepam for benzodiazepines and chlorpromazine for antipsychotics.

Tristan Ronald Ling, Peter Gee, Juanita Westbury, Ivan Bindoff, Gregory Peterson

J Med Internet Res 2017;19(8):e283