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Skip search results from other journals and go to results- 3 Journal of Medical Internet Research
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Terms related to benzodiazepines overall showed a general increase in frequency over time (Figure 2), with a gradual increase from 2013 to 2016, a gradual decrease from 2016 to 2019, and a subsequent increase from 2020 to 2022.
J Med Internet Res 2025;27:e58902
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The majority of these overdose fatalities involved the synthetic opioid fentanyl (which is often illicitly manufactured and can be hundreds of times more powerful than morphine [6]), as well as other adulterants including xylazine [7] and benzodiazepines [8]. All can be present in a drug without people’s knowledge.
JMIR Form Res 2024;8:e56755
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Finally, the importance of support and encouragement cannot be underestimated, as it was also associated with successful discontinuation in the EMPOWER study, in which a deprescribing brochure on benzodiazepines was mailed to older adult patients [41].
Fifth, blended care was implemented pragmatically, that is, without a protocol.
JMIR Form Res 2023;7:e43738
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For example, the use of medications such as antipsychotics, benzodiazepines, and sedative hypnotic “Z-drugs,” to manage delirium and agitation for hospitalized patients remains highly prevalent despite considerable risks associated with their use and guidelines that recommend their avoidance in older adults [12-15]. In this context, there are numerous factors that are stressful for physicians which promote System 1 thinking.
JMIR Res Protoc 2022;11(4):e31464
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Associated contributory factors to dementia, such as excessive prescription of medications (eg, benzodiazepines [BZD]), poor rates of health screening, and high illiteracy, have also been found to be highly prevalent in West Virginia and the rest of the Appalachia [7-9]. Thus, caring for patients with dementia is challenging, especially in Appalachia, because of the complexities that arise due to the increased burden of aforementioned comorbidities and contributory factors [10].
JMIR Med Inform 2020;8(8):e18389
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Remaining symptomatic was defined herein as having insomnia that is at least moderate in severity, based on a Pittsburgh Sleep Quality Index (PSQI) score of greater than 5.5 [15,17,18] after the use of hypnotics including nonbenzodiazepines, benzodiazepines, melatonin receptor agonists, orexin receptor antagonists, and antidepressants.
Each participant’s treatment history was confirmed by their prescribing clinician and by chart review.
J Med Internet Res 2019;21(4):e12686
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Additionally, a measure of sedative load was calculated for each resident: the average daily dose for each medication was determined and compared with the World Health Organization’s Defined Daily Dose (DDD) values [40]; to enable reporting at a nursing home level, daily doses were converted to an equivalent strength of diazepam for benzodiazepines and chlorpromazine for antipsychotics.
J Med Internet Res 2017;19(8):e283
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