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Tablet- and Group-Based Multicomponent Cognitive Stimulation for Older Adults With Mild Cognitive Impairment: Single-Group Pilot Study and Protocol for Randomized Controlled Trial

Tablet- and Group-Based Multicomponent Cognitive Stimulation for Older Adults With Mild Cognitive Impairment: Single-Group Pilot Study and Protocol for Randomized Controlled Trial

Mild cognitive impairment (MCI) is the stage between normal aging and dementia, including probable Alzheimer disease, characterized by noticeable cognitive deficits that do not impair daily functioning significantly [1-3]. The cognitive domains affected by MCI include learning and memory, language, visuospatial abilities, executive functions, and psychomotor skills. Notably, evident impairment in any of these domains is sufficient for an MCI diagnosis [4].

Khanitin Jornkokgoud, Pattrawadee Makmee, Peera Wongupparaj, Alessandro Grecucci

JMIR Res Protoc 2025;14:e64465

A Multivariable Prediction Model for Mild Cognitive Impairment and Dementia: Algorithm Development and Validation

A Multivariable Prediction Model for Mild Cognitive Impairment and Dementia: Algorithm Development and Validation

Mild cognitive impairment (MCI) is the transitional phase between normal aging and dementia [1]. According to a systematic review of global prevalence, MCI is estimated to affect approximately 15.56% of community-dwelling adults aged 50 years and older [2]. The annual progression rate of MCI to dementia, which is characterized by acquired memory loss that interferes with daily functioning [3], is believed to range from 12% to 17% [1].

Sarah Soyeon Oh, Bada Kang, Dahye Hong, Jennifer Ivy Kim, Hyewon Jeong, Jinyeop Song, Minkyu Jeon

JMIR Med Inform 2024;12:e59396

Investigating Acoustic and Psycholinguistic Predictors of Cognitive Impairment in Older Adults: Modeling Study

Investigating Acoustic and Psycholinguistic Predictors of Cognitive Impairment in Older Adults: Modeling Study

It is estimated that approximately one-third of adults aged 65 years and older in the United States have mild cognitive impairment (MCI) or dementia [1]. Given the high prevalence of MCI and dementia, better methods are needed for earlier identification. Biomarkers associated with future cognitive decline can be evident decades before the deficits are clinically detected [2].

Varsha D Badal, Jenna M Reinen, Elizabeth W Twamley, Ellen E Lee, Robert P Fellows, Erhan Bilal, Colin A Depp

JMIR Aging 2024;7:e54655

The Dual Task Ball Balancing Test and Its Association With Cognitive Function: Algorithm Development and Validation

The Dual Task Ball Balancing Test and Its Association With Cognitive Function: Algorithm Development and Validation

Individuals with mild cognitive impairment (MCI) and higher cognitive reserve can delay the development of dementia. Thus, assessment of cognitive reserve is important to predict an individual’s functional state and prognosis. In addition, cognitive reserve can be a powerful therapeutic target, as increasing cognitive reserve might reduce disability.

Barry Greene, Sean Tobyne, Ali Jannati, Killian McManus, Joyce Gomes Osman, Russell Banks, Ranjit Kher, John Showalter, David Bates, Alvaro Pascual-Leone

J Med Internet Res 2024;26:e49794

Performance Differences of a Touch-Based Serial Reaction Time Task in Healthy Older Participants and Older Participants With Cognitive Impairment on a Tablet: Experimental Study

Performance Differences of a Touch-Based Serial Reaction Time Task in Healthy Older Participants and Older Participants With Cognitive Impairment on a Tablet: Experimental Study

Some SRTT studies were conducted with patients with AD as the clinical sample, whereas others were conducted with patients with mild cognitive impairment (MCI; for reviews, refer to the studies by de Wit et al [8] and van Halteren-van Tilborg et al [14]). Overall, there are mixed findings on the association between SRTT performance and cognitive impairment (such as AD, which can be a later stage of MCI).

Christian Mychajliw, Heiko Holz, Nathalie Minuth, Kristina Dawidowsky, Gerhard Wilhelm Eschweiler, Florian Gerhard Metzger, Franz Wortha

JMIR Aging 2024;7:e48265

Digital Storytelling Intervention for Enhancing the Social Participation of People With Mild Cognitive Impairment: Co-Design and Usability Study

Digital Storytelling Intervention for Enhancing the Social Participation of People With Mild Cognitive Impairment: Co-Design and Usability Study

Some memory retrieval interventions may combine multiple functions of the interventions, such as people with MCI simultaneously reminiscing and sharing their recollections [23]. Challenges in using technology remain an unsolved issue; people with MCI typically exhibit lower digital literacy [24].

Di Zhu, Abdullah Al Mahmud, Wei Liu

JMIR Aging 2024;7:e54138