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Given the anticipated overlap of these conditions, ≈20% (n=90) of women will have at least one maternal metabolic disease of interest (secondary outcome).
Study data are collected using paper case report forms. These paper documents will be kept in a locked cupboard accessible only to local research staff. Patient information is collected and stored by the investigators in a confidential REDCap (Research Electronic Data Capture system; Vanderbilt University), with password protection and restricted access.
JMIR Res Protoc 2025;14:e72542
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Safety and Efficacy of Modular Digital Psychotherapy for Social Anxiety: Randomized Controlled Trial
Overall, the treatment remained safe, acceptable, and effective, significantly improving symptoms of social anxiety in 2 separate samples compared to a waitlist control group (RCT 1: n=102; RCT 2: n=267). This enabled the development of mechanistically defined cognitive assessment modules to personalize treatment delivery and, hopefully, further improve efficacy.
J Med Internet Res 2025;27:e64138
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We reviewed 102 surgical pathology reports from 102 patients and excluded reports if they were from other organ sites (n=10), benign (n=2), cytopathology (n=5), or outside review (n=1). We included 84 reports for analysis. The study flowchart is shown in Figure 2.
Flowchart of the study design and analysis. *The concordance rate was calculated as the total number of concordant answers/total number of answers for each of the 12 medical question answering (MQA).
JMIR Form Res 2025;9:e64544
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Correction: Stress Reduction in Perioperative Care: Feasibility Randomized Controlled Trial
J Med Internet Res 2025;27:e73608
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Extended Reality (XR) in Pediatric Acute and Chronic Pain: Systematic Review and Evidence Gap Map
A much smaller number of studies (n=6) examined the utility of VR in chronic pain populations including intensive pain rehabilitation (n=1) [112], chronic burn dressing (n=1) [113], chronic musculoskeletal pain (n=1) [114], chronic cancer-related pain (n=2) [115,116], and chronic abdominal pain (n=1) [117]. See Figure 2 for the summary of pain populations included across the studies.
JMIR Pediatr Parent 2025;8:e63854
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The proportion of sedentary individuals increased from 38% (n=14,177) in 2019 to 52% (n=19,510) in 2020 and remained elevated at 51% (n=18,972) in 2022, while the proportion of active individuals dropped from 8% (n=2857) to 6% (n=2352) in 2020 before returning to 8% (n=2877) in 2022 (Figure 4). Figure 4 illustrates shifts in activity levels throughout the study period.
J Med Internet Res 2025;27:e68199
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The planned effectiveness study sample size is 6600 enrolled patients, including approximately 300 (4.56%) from each of the 22 participating clinics (Bronx: n=6, 27%; Indiana: n=16, 73%).
For the implementation interviews, we will use snowball sampling to identify the most relevant informants across clinics of different sizes.
JMIR Res Protoc 2025;14:e60471
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We have randomized 22 administrative wards in a 1:1 ratio and aim to enroll about 72 adolescent girls and young women from each (total N=about 1584) to receive either the Tu’Washindi intervention plus usual HIV prevention services, or usual HIV prevention services alone.
JMIR Res Protoc 2025;14:e55931
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Breast Cancer Vlogs on YouTube: Descriptive and Content Analyses
JMIR Infodemiology 2025;5:e66812
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The AI Reviewer: Evaluating AI’s Role in Citation Screening for Streamlined Systematic Reviews
Hence, 121 citations (n=21, 17.4% included and n=100, 82.6% excluded) were tested against predefined eligibility criteria using Chat GPT 3.5 (version September 25, 2023), Chat GPT 4 (version September 25, 2023), Google Bard (version 1.15; released on September 2, 2023), Meta Llama 2 (70b parameters, version 2.1.1; released on October 10, 2023), and Claude AI 2 (version 1.3; released on July 11, 2023). We used descriptive statistics to evaluate sensitivity, specificity, and overall accuracy.
JMIR Form Res 2025;9:e58366
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