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The Butterworth filter is expressed using equation 1:
where y(t) is the filtered signal; x(t) is the input signal; fc is the cutoff frequency; f is the frequency of the signal; and n is the order of the filter.
In this study, an order of 4 was used for the Butterworth filters because it provides a smooth yet sufficiently steep roll-off in the transition band. While higher-order filters provide sharper roll-offs, they also require more computational resources.
JMIR Aging 2025;8:e65629
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From the extended-cosine models, we extracted measures of 24-hour robustness (pseudo-F statistic, indicating how well the observed data fits the 24-hour curve); activity onset time (up-mesor, the time which the modeled activity level passes the middle modeled rhythm height prior to the peak); and activity offset time (down-mesor or the time which the modeled activity level passes the middle modeled rhythm height prior to the nadir).
JMIR Aging 2025;8:e67294
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Telemedicine as a tool for PrEP delivery during the COVID-19 pandemic in a large HIV prevention service in Rio de Reference 39: Organização, processamento, análise e interpretação de dados: o desafio da triangulação Reference 43: A (in)visibilidade gênero no currículo e na prática de duas especialidades médicas Reference 58: Saúde de Lésbicas, Gays, Bissexuais, Travestis e Transexuais: da Formação Médica à Atuação Reference 59: Gênero e Sexualidade nas Escolas Médicas Federais do Brasil: uma Análise de Projetos Pedagógicos
J Med Internet Res 2025;27:e67445
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