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Optimizing Initial Vancomycin Dosing in Hospitalized Patients Using Machine Learning Approach for Enhanced Therapeutic Outcomes: Algorithm Development and Validation Study

Optimizing Initial Vancomycin Dosing in Hospitalized Patients Using Machine Learning Approach for Enhanced Therapeutic Outcomes: Algorithm Development and Validation Study

Of these, we selected the first TDM consultation data (n=540) in the same patients if multiple were requested, and excluded patients aged 18 years or younger (n=22), those undergoing hemodialysis (n=38) or estimated glomerular filtration rate (e GFR) less than 15 m L/min/1.73 m2 (n=10), patients with total medication time of less than 48 hours (n=43), patients with less than 3 medication doses (n=6), patients with vancomycin trough concentrations below the lower limit of quantification (n=4), patients with no

Heonyi Lee, Yi-Jun Kim, Jin-Hong Kim, Soo-Kyung Kim, Tae-Dong Jeong

J Med Internet Res 2025;27:e63983

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