Prediction of Sepsis in the Intensive Care Unit With Minimal Electronic Health Record Data: A Machine Learning Approach

Thomas Desautels   ¹ , PhD ;   Jacob Calvert   ¹ , BS ;   Jana Hoffman   ¹ , PhD ;   Melissa Jay   ¹ , BS ;   Yaniv Kerem   ^{2, 3} , MD ;   Lisa Shieh   ⁴ , MD, PhD ;   David Shimabukuro   ⁵ , MD ;   Uli Chettipally   ^{6, 7} , MD, MPH ;   Mitchell D Feldman   ⁸ , MD, MPhil ;   Chris Barton   ⁷ , MD ;   David J Wales   ⁹ , ScD ;   Ritankar Das   ¹ , MSc

¹ Dascena, Inc, Hayward, CA, United States

² Stanford University School of Medicine, Department of Clinical Informatics, Stanford, CA, United States

³ Kaiser Permanente Redwood City Medical Center, Department of Emergency Medicine, Redwood City, CA, United States

⁴ Stanford University School of Medicine, Department of Medicine, Stanford, CA, United States

⁵ Division of Critical Care Medicine, Department of Anesthesia and Perioperative Care, University of California San Francisco, San Francisco, CA, United States

⁶ Kaiser Permanente South San Francisco Medical Center, Department of Emergency Medicine, South San Francisco, CA, United States

⁷ Department of Emergency Medicine, University of California San Francisco, San Francisco, CA, United States

⁸ Division of General Internal Medicine, Department of Medicine, University of California San Francisco, San Francisco, CA, United States

⁹ Department of Chemistry, University of Cambridge, Cambridge, United Kingdom