TY - JOUR AU - Muliokela, Rosemary K AU - Banda, Kuwani AU - Hussen, Abdulaziz Mohammed AU - Malumo, Sarai Bvulani AU - Kashoka, Andrew AU - Mwiche, Angel AU - Chiboma, Innocent AU - Barreix, Maria AU - Nyirenda, Muyereka AU - Sithole, Zvanaka AU - Ratanaprayul, Natschja AU - Endehabtu, Berhanu Fikadie AU - Telake, Hanna Abayneh AU - Weldeab, Adane AU - Probert, William J M AU - Tunçalp, Ӧzge AU - Maya, Ernest AU - Woldetsadik, Mulatu AU - Tilahun, Binyam AU - Guure, Chris AU - Senya, Kafui AU - Say, Lale AU - Tamrat, Tigest PY - 2025 DA - 2025/2/7 TI - Implementation of WHO SMART Guidelines-Digital Adaptation Kits in Pathfinder Countries in Africa: Processes and Early Lessons Learned JO - JMIR Med Inform SP - e58858 VL - 13 KW - guidelines KW - reproductive health KW - maternal health KW - antenatal care KW - clinical decision support KW - clinical decision support systems KW - digital health KW - HIV/AIDS KW - family planning KW - electronic medical records KW - electronic health record KW - standards KW - interoperability KW - system uptake KW - digital health governance AB - Background: The adoption of digital systems requires processes for quality assurance and uptake of standards to achieve universal health coverage. The World Health Organization developed the Digital Adaptation Kits (DAKs) within the SMART (Standards-based, Machine-readable, Adaptive, Requirements-based, and Testable) guidelines framework to support the uptake of standards and recommendations through digital systems. DAKs are a software-neutral mechanism for translating narrative guidelines to support the design of digital systems. However, a systematic process is needed to implement and ensure the impact of DAKs in country contexts. Objective: This paper details the structured process and stepwise approach to customize the DAKs to the national program and digital context in 5 countries in Africa with diverse program guideline uptake and significant digital health investments: Ethiopia, Ghana, Malawi, Zambia, and Zimbabwe. All these countries have existing digital systems, which have the potential to be updated with the DAKs. Methods: A DAK assessment tool was developed and used to assess guideline digitization readiness and opportunities for system uptake in each country. Multistakeholder teams were established to conduct the content review and alignment of the generic DAK to national guidelines and protocols through a series of stakeholder consultations, including stakeholder orientation, content review and alignment, content validation, and software update meetings. Implementation (Results): Country adaptation processes identified requirements for national-level contextualization and highlighted opportunities for refinement of DAKs. Quality assurance of the content during the content review and validation processes ensured alignment with national protocols. Adaptation processes also facilitated the adoption of the DAKs approach into national guidelines and strategic documents for sexual and reproductive health. Conclusions: Country experiences offered early insights into the opportunities and benefits of a structured approach to digitalizing primary health care services. They also highlighted how this process can be continuously refined and sustained to enhance country-level impact. SN - 2291-9694 UR - https://medinform.jmir.org/2025/1/e58858 UR - https://doi.org/10.2196/58858 DO - 10.2196/58858 ID - info:doi/10.2196/58858 ER -