TY - JOUR AU - Hu, Zhengyong AU - Wang, Anran AU - Duan, Yifan AU - Zhou, Jiayin AU - Hu, Wanfei AU - Wu, Sizhu PY - 2024 DA - 2024/9/30 TI - Toward Better Semantic Interoperability of Data Element Repositories in Medicine: Analysis Study JO - JMIR Med Inform SP - e60293 VL - 12 KW - data element repository KW - FAIR KW - ISO/IEC 11179 KW - metadata KW - semantic interoperability AB - Background: Data element repositories facilitate high-quality medical data sharing by standardizing data and enhancing semantic interoperability. However, the application of repositories is confined to specific projects and institutions. Objective: This study aims to explore potential issues and promote broader application of data element repositories within the medical field by evaluating and analyzing typical repositories. Methods: Following the inclusion of 5 data element repositories through a literature review, a novel analysis framework consisting of 7 dimensions and 36 secondary indicators was constructed and used for evaluation and analysis. Results: The study’s results delineate the unique characteristics of different repositories and uncover specific issues in their construction. These issues include the absence of data reuse protocols and insufficient information regarding the application scenarios and efficacy of data elements. The repositories fully comply with only 45% (9/20) of the subprinciples for Findable and Reusable in the FAIR principle, while achieving a 90% (19/20 subprinciples) compliance rate for Accessible and 67% (10/15 subprinciples) for Interoperable. Conclusions: The recommendations proposed in this study address the issues to improve the construction and application of repositories, offering valuable insights to data managers, computer experts, and other pertinent stakeholders. SN - 2291-9694 UR - https://medinform.jmir.org/2024/1/e60293 UR - https://doi.org/10.2196/60293 UR - http://www.ncbi.nlm.nih.gov/pubmed/39348178 DO - 10.2196/60293 ID - info:doi/10.2196/60293 ER -