TY - JOUR AU - Arend, Ann-Kathrin AU - Kaiser, Tim AU - Pannicke, Björn AU - Reichenberger, Julia AU - Naab, Silke AU - Voderholzer, Ulrich AU - Blechert, Jens PY - 2023 DA - 2023/2/23 TI - Toward Individualized Prediction of Binge-Eating Episodes Based on Ecological Momentary Assessment Data: Item Development and Pilot Study in Patients With Bulimia Nervosa and Binge-Eating Disorder JO - JMIR Med Inform SP - e41513 VL - 11 KW - idiographic KW - individualized KW - N of 1 KW - Ecological Momentary Assessment (EMA) KW - Just-In-Time Adaptive Intervention (JITAI) KW - binge eating KW - literature research KW - focus group KW - prediction algorithm KW - machine learning KW - Best Items Scales that are Cross-validated, Unit-weighted, Informative and Transparent KW - BISCUIT AB - Background: Prevention of binge eating through just-in-time mobile interventions requires the prediction of respective high-risk times, for example, through preceding affective states or associated contexts. However, these factors and states are highly idiographic; thus, prediction models based on averages across individuals often fail. Objective: We developed an idiographic, within-individual binge-eating prediction approach based on ecological momentary assessment (EMA) data. Methods: We first derived a novel EMA-item set that covers a broad set of potential idiographic binge-eating antecedents from literature and an eating disorder focus group (n=11). The final EMA-item set (6 prompts per day for 14 days) was assessed in female patients with bulimia nervosa or binge-eating disorder. We used a correlation-based machine learning approach (Best Items Scale that is Cross-validated, Unit-weighted, Informative, and Transparent) to select parsimonious, idiographic item subsets and predict binge-eating occurrence from EMA data (32 items assessing antecedent contextual and affective states and 12 time-derived predictors). Results: On average 67.3 (SD 13.4; range 43-84) EMA observations were analyzed within participants (n=13). The derived item subsets predicted binge-eating episodes with high accuracy on average (mean area under the curve 0.80, SD 0.15; mean 95% CI 0.63-0.95; mean specificity 0.87, SD 0.08; mean sensitivity 0.79, SD 0.19; mean maximum reliability of rD 0.40, SD 0.13; and mean rCV 0.13, SD 0.31). Across patients, highly heterogeneous predictor sets of varying sizes (mean 7.31, SD 1.49; range 5-9 predictors) were chosen for the respective best prediction models. Conclusions: Predicting binge-eating episodes from psychological and contextual states seems feasible and accurate, but the predictor sets are highly idiographic. This has practical implications for mobile health and just-in-time adaptive interventions. Furthermore, current theories around binge eating need to account for this high between-person variability and broaden the scope of potential antecedent factors. Ultimately, a radical shift from purely nomothetic models to idiographic prediction models and theories is required. SN - 2291-9694 UR - https://medinform.jmir.org/2023/1/e41513 UR - https://doi.org/10.2196/41513 UR - http://www.ncbi.nlm.nih.gov/pubmed/36821359 DO - 10.2196/41513 ID - info:doi/10.2196/41513 ER -