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  <front>
    <journal-meta>
      <journal-id journal-id-type="publisher-id">JMI</journal-id>
      <journal-id journal-id-type="nlm-ta">JMIR Med Inform</journal-id>
      <journal-title>JMIR Medical Informatics</journal-title>
      <issn pub-type="epub">2291-9694</issn>
      <publisher>
        <publisher-name>JMIR Publications</publisher-name>
        <publisher-loc>Toronto, Canada</publisher-loc>
      </publisher>
    </journal-meta>
    <article-meta>
      <article-id pub-id-type="publisher-id">v13i1e73495</article-id>
      <article-id pub-id-type="pmid">40987450</article-id>
      <article-id pub-id-type="doi">10.2196/73495</article-id>
      <article-categories>
        <subj-group subj-group-type="heading">
          <subject>Short Paper</subject>
        </subj-group>
        <subj-group subj-group-type="article-type">
          <subject>Short Paper</subject>
        </subj-group>
      </article-categories>
      <title-group>
        <article-title>Virtual Transition of Care Clinics and Associated Readmission Rates: 3-Year Retrospective Cohort Study</article-title>
      </title-group>
      <contrib-group>
        <contrib contrib-type="editor">
          <name>
            <surname>Benis</surname>
            <given-names>Arriel</given-names>
          </name>
        </contrib>
      </contrib-group>
      <contrib-group>
        <contrib contrib-type="reviewer">
          <name>
            <surname>Speck</surname>
            <given-names>Peter</given-names>
          </name>
        </contrib>
        <contrib contrib-type="reviewer">
          <name>
            <surname>Bier-Laning</surname>
            <given-names>Carol M</given-names>
          </name>
        </contrib>
        <contrib contrib-type="reviewer">
          <name>
            <surname>Greenup</surname>
            <given-names>Edwin Phillip</given-names>
          </name>
        </contrib>
      </contrib-group>
      <contrib-group>
        <contrib id="contrib1" contrib-type="author" corresp="yes">
          <name name-style="western">
            <surname>Horman</surname>
            <given-names>Sarah F</given-names>
          </name>
          <degrees>MD</degrees>
          <xref rid="aff1" ref-type="aff">1</xref>
          <address>
            <institution>Department of Medicine</institution>
            <institution>University of California, San Diego</institution>
            <addr-line>200 West Arbor Drive MC 8485</addr-line>
            <addr-line>San Diego, CA, 92103</addr-line>
            <country>United States</country>
            <fax>1 619 543 8255</fax>
            <phone>1 619 471 9186</phone>
            <email>shorman@health.ucsd.edu</email>
          </address>
          <xref rid="aff2" ref-type="aff">2</xref>
          <ext-link ext-link-type="orcid">https://orcid.org/0000-0002-9796-3561</ext-link>
        </contrib>
        <contrib id="contrib2" contrib-type="author">
          <name name-style="western">
            <surname>Kviatkovsky</surname>
            <given-names>Milla</given-names>
          </name>
          <degrees>DO, MPH</degrees>
          <xref rid="aff1" ref-type="aff">1</xref>
          <ext-link ext-link-type="orcid">https://orcid.org/0000-0003-4572-3328</ext-link>
        </contrib>
        <contrib id="contrib3" contrib-type="author">
          <name name-style="western">
            <surname>Castillo</surname>
            <given-names>Edward</given-names>
          </name>
          <degrees>PhD, MPH</degrees>
          <xref rid="aff3" ref-type="aff">3</xref>
          <ext-link ext-link-type="orcid">https://orcid.org/0000-0002-7464-295X</ext-link>
        </contrib>
        <contrib id="contrib4" contrib-type="author">
          <name name-style="western">
            <surname>Maysent</surname>
            <given-names>Patricia</given-names>
          </name>
          <degrees>MBA, MPH</degrees>
          <xref rid="aff2" ref-type="aff">2</xref>
          <ext-link ext-link-type="orcid">https://orcid.org/0009-0002-3120-3196</ext-link>
        </contrib>
        <contrib id="contrib5" contrib-type="author">
          <name name-style="western">
            <surname>VanDenBerg</surname>
            <given-names>Chad</given-names>
          </name>
          <degrees>MPH</degrees>
          <xref rid="aff2" ref-type="aff">2</xref>
          <ext-link ext-link-type="orcid">https://orcid.org/0009-0009-2853-8754</ext-link>
        </contrib>
        <contrib id="contrib6" contrib-type="author">
          <name name-style="western">
            <surname>Bell</surname>
            <given-names>John</given-names>
          </name>
          <degrees>MD, MPH</degrees>
          <xref rid="aff1" ref-type="aff">1</xref>
          <ext-link ext-link-type="orcid">https://orcid.org/0000-0003-3116-1774</ext-link>
        </contrib>
        <contrib id="contrib7" contrib-type="author">
          <name name-style="western">
            <surname>Longhurst</surname>
            <given-names>Christopher A</given-names>
          </name>
          <degrees>MD, MS</degrees>
          <xref rid="aff2" ref-type="aff">2</xref>
          <xref rid="aff4" ref-type="aff">4</xref>
          <ext-link ext-link-type="orcid">https://orcid.org/0000-0003-4908-6856</ext-link>
        </contrib>
      </contrib-group>
      <aff id="aff1">
        <label>1</label>
        <institution>Department of Medicine</institution>
        <institution>University of California, San Diego</institution>
        <addr-line>San Diego, CA</addr-line>
        <country>United States</country>
      </aff>
      <aff id="aff2">
        <label>2</label>
        <institution>Jacobs Center for Health Innovation</institution>
        <institution>University of California San Diego Health</institution>
        <addr-line>San Diego, CA</addr-line>
        <country>United States</country>
      </aff>
      <aff id="aff3">
        <label>3</label>
        <institution>Department of Emergency Medicine</institution>
        <institution>University of California, San Diego</institution>
        <addr-line>San Diego, CA</addr-line>
        <country>United States</country>
      </aff>
      <aff id="aff4">
        <label>4</label>
        <institution>Department of Biomedical Informatics</institution>
        <institution>University of California San Diego</institution>
        <addr-line>San Diego, CA</addr-line>
        <country>United States</country>
      </aff>
      <author-notes>
        <corresp>Corresponding Author: Sarah F Horman <email>shorman@health.ucsd.edu</email></corresp>
      </author-notes>
      <pub-date pub-type="collection">
        <year>2025</year>
      </pub-date>
      <pub-date pub-type="epub">
        <day>23</day>
        <month>9</month>
        <year>2025</year>
      </pub-date>
      <volume>13</volume>
      <elocation-id>e73495</elocation-id>
      <history>
        <date date-type="received">
          <day>5</day>
          <month>3</month>
          <year>2025</year>
        </date>
        <date date-type="rev-request">
          <day>15</day>
          <month>4</month>
          <year>2025</year>
        </date>
        <date date-type="rev-recd">
          <day>4</day>
          <month>6</month>
          <year>2025</year>
        </date>
        <date date-type="accepted">
          <day>11</day>
          <month>8</month>
          <year>2025</year>
        </date>
      </history>
      <copyright-statement>©Sarah F Horman, Milla Kviatkovsky, Edward Castillo, Patricia Maysent, Chad VanDenBerg, John Bell, Christopher A Longhurst. Originally published in JMIR Medical Informatics (https://medinform.jmir.org), 23.09.2025.</copyright-statement>
      <copyright-year>2025</copyright-year>
      <license license-type="open-access" xlink:href="https://creativecommons.org/licenses/by/4.0/">
        <p>This is an open-access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work, first published in JMIR Medical Informatics, is properly cited. The complete bibliographic information, a link to the original publication on https://medinform.jmir.org/, as well as this copyright and license information must be included.</p>
      </license>
      <self-uri xlink:href="https://medinform.jmir.org/2025/1/e73495" xlink:type="simple"/>
      <abstract>
        <sec sec-type="background">
          <title>Background</title>
          <p>Hospital readmissions pose a significant burden on patients, health care providers, and systems, with an estimated annual cost of $17 billion. Timely follow-up within 7 days postdischarge is known to reduce readmissions but is often limited by access constraints. While transitions of care clinics have demonstrated benefits in reducing unplanned readmissions, physical space requirements can be logistically and financially challenging.</p>
        </sec>
        <sec sec-type="objective">
          <title>Objective</title>
          <p>This study aimed to evaluate the effectiveness of a virtual transitions of care (VToC) clinic in reducing 30-day hospital readmissions and improving postdischarge care coordination.</p>
        </sec>
        <sec sec-type="methods">
          <title>Methods</title>
          <p>University of California, San Diego Health implemented a hospitalist-led VToC clinic designed to support clinical management, medication reconciliation, primary care provider repatriation, and specialty care navigation. The study included 2314 patients seen in the VToC clinic between September 2021 and September 2024. Outcomes were compared to a benchmark group using regression analysis to assess the impact on 30-day readmission rates.</p>
        </sec>
        <sec sec-type="results">
          <title>Results</title>
          <p>The 30-day readmission rate for VToC patients was 14.9% (344/2314), significantly lower than the 20.1% (4659/23,129) observed in the benchmark group (<italic>P</italic>&#60;.001). Regression analysis indicated that patients not participating in the VToC clinic had a higher likelihood of readmission (odds ratio=1.37; 95% CI=1.21-1.54; <italic>P</italic>&#60;.001). The most substantial reduction in readmissions was observed among patients with moderate readmission risk (LACE+ score of 50-75).</p>
        </sec>
        <sec sec-type="conclusions">
          <title>Conclusions</title>
          <p>VToC clinics are a feasible and effective strategy for enhancing postdischarge care, reducing hospital readmissions, and improving care coordination. This model supports the quadruple aim by promoting better health outcomes, improved patient experience, cost-efficiency, and care equity.</p>
        </sec>
      </abstract>
      <kwd-group>
        <kwd>transitions of care</kwd>
        <kwd>telehealth</kwd>
        <kwd>telemedicine</kwd>
        <kwd>hospital medicine</kwd>
        <kwd>quality and patient safety</kwd>
        <kwd>health care utilization</kwd>
      </kwd-group>
    </article-meta>
  </front>
  <body>
    <sec sec-type="introduction">
      <title>Introduction</title>
      <p>Unexpected return to the hospital reflects systemic challenges in health care delivery and places a financial strain on the nation’s health system [<xref ref-type="bibr" rid="ref1">1</xref>]. Postdischarge follow-ups within 7 days is a well-established protective mechanism to reduce the risk of readmission and mitigate health care disparities but are limited by access challenges and physician shortages [<xref ref-type="bibr" rid="ref2">2</xref>-<xref ref-type="bibr" rid="ref5">5</xref>]. Transitions of care clinics have shown benefit in readmission reduction but may be cost prohibitive and logistically challenging [<xref ref-type="bibr" rid="ref4">4</xref>,<xref ref-type="bibr" rid="ref5">5</xref>]. Virtual postdischarge clinics may achieve similar benefits with fewer costs and present an opportunity to enhance postdischarge access [<xref ref-type="bibr" rid="ref6">6</xref>].</p>
    </sec>
    <sec sec-type="methods">
      <title>Methods</title>
      <sec>
        <title>Overview</title>
        <p>At the University of California, San Diego Health, we implemented a hospital medicine physician-led virtual transitions of care (VToC) clinic, focused on postdischarge clinical management, medication reconciliation, primary care provider (PCP) repatriation, and specialty care navigation, with the aim of reducing repeat hospitalization.</p>
        <p>Based on internal pilot data showing a favorable readmission impact for patients with moderate risk of readmission, we created a criteria-based order to trigger referral for patients (aged 18 years and older) discharged from the hospital medicine service line. The discharging providers were automatically prompted at discharge to refer patients to the clinic if patients had a LACE+ index (a readmission risk prediction index based on length of stay, acuity of admission, comorbidities, and emergency department visit history) between 50 and 75 [<xref ref-type="bibr" rid="ref7">7</xref>]. Patients with LACE+ scores outside this range could be referred at provider discretion. Patients were excluded from appointment scheduling if they were discharged to a care facility or hospice or had an existing PCP appointment within 7 days of discharge.</p>
        <p>The virtual clinic was supported by 12 hospitalists, 2 medical assistants, 1 pharmacist and an on-demand interpreter service. Medical assistants contacted eligible patients to schedule web-based video visits. VToC visits were occasionally converted to telephone encounters when patients faced technical barriers, which occurred in fewer than 5% of cases and thus were not considered a distinct comparison group for analysis. Patients received phone call reminders 1 business day prior to scheduled appointments. Pharmacists conducted previsit medication reviews to identify fill history gaps, dosing inconsistencies, and potential drug-drug interactions. Note templates guided VToC providers in addressing medication management, social determinants of health, barriers to follow-up, and care coordination. A standardized electronic handoff was routed to the patient’s PCP and relevant specialists summarizing the reason for hospitalization, follow-up needs, and timing recommendations. Additionally, post-VToC visit communication was sent to the discharging hospitalist to highlight potential care lapses and support quality improvement efforts.</p>
        <p>Data were collected from the electronic health records using standard SQL queries. These included demographics (ages grouped as &#60;45, 45-64, and ≥65 years; sex; and race and ethnicity); VToC status (yes or no); PCP (University of California San Diego or other); LACE+ score (&#60;50, 50-75, or &#62;75); and 30-day all-cause readmission. Patient characteristics were analyzed by VToC status (yes or no). A VToC status of “no” indicates patients who were discharged from the medicine service line to home and not seen in our clinic (because they did not meet eligibility criteria or could not be reached). Patients were excluded from analysis if they had missing demographic or clinical data. Readmission rates were analyzed for VToC status and by LACE+ score. Chi-square analysis was used to compare characteristics by VToC status with a <italic>P</italic>&#60;.05 considered significant. Readmission rates (%) by VToC status stratified by LACE+ decile are reported. Error bars were calculated using 95% CIs. A multivariable logistic regression analysis was performed to assess independent associations with unplanned hospital readmission. Variables included in the model included age group, sex, race and ethnicity, PCP affiliation (UCSD versus non-UCSD), LACE+ score, and VToC enrollment. All analyses were conducted using the SPSS Statistics software suite (version 27.0; IBM Corporation).</p>
      </sec>
      <sec>
        <title>Ethical Considerations</title>
        <p>This study was conducted in an Institutional Review Board–exempt fashion in accordance with the ethical standards of the University of California San Diego Human Research Protection Program and the Office for Human Research Protections and adhered to the Helsinki Declaration of 1975, as revised in 2000.</p>
      </sec>
    </sec>
    <sec sec-type="results">
      <title>Results</title>
      <p>There were 25,970 patients identified for the study period of September 1, 2021, through September 17, 2024. A total of 527 (0.02%) patients had missing data and were excluded from the analysis. Of the 25,443 patients included in the study, 2314 (9.1%) were seen in VToC after discharge and 23,129 (90.9%) had standard of care follow-up. <xref ref-type="table" rid="table1">Table 1</xref> shows the demographic comparisons of patients who were seen in VToC versus those who were not for the same time period.</p>
      <table-wrap position="float" id="table1">
        <label>Table 1</label>
        <caption>
          <p>Demographics of virtual transitions of care (VToC) and non-VToC patients (N=25,443).</p>
        </caption>
        <table width="1000" cellpadding="5" cellspacing="0" border="1" rules="groups" frame="hsides">
          <col width="30"/>
          <col width="300"/>
          <col width="200"/>
          <col width="200"/>
          <col width="200"/>
          <col width="70"/>
          <thead>
            <tr valign="top">
              <td colspan="2">
                <break/>
              </td>
              <td>VToC (n=2314)</td>
              <td>Non-VToC (n=23,129)</td>
              <td>Total (N=25,443)</td>
              <td><italic>P</italic> value</td>
            </tr>
          </thead>
          <tbody>
            <tr valign="top">
              <td colspan="2">
                <bold>Age range, (y), n (%)</bold>
              </td>
              <td/>
              <td/>
              <td/>
              <td>.40</td>
            </tr>
            <tr valign="top">
              <td>
                <break/>
              </td>
              <td>&#60;45</td>
              <td>558 (24.1)</td>
              <td>5829 (25.2)</td>
              <td>6387 (25.1)</td>
              <td/>
            </tr>
            <tr valign="top">
              <td>
                <break/>
              </td>
              <td>45-64</td>
              <td>861 (37.2)</td>
              <td>8325 (36)</td>
              <td>9186 (36.1)</td>
              <td/>
            </tr>
            <tr valign="top">
              <td>
                <break/>
              </td>
              <td>≥65</td>
              <td>895 (38.7)</td>
              <td>8975 (38.8)</td>
              <td>9870 (38.8)</td>
              <td/>
            </tr>
            <tr valign="top">
              <td colspan="2">
                <bold>Sex, n (%)</bold>
              </td>
              <td/>
              <td/>
              <td/>
              <td>&#60;.001</td>
            </tr>
            <tr valign="top">
              <td>
                <break/>
              </td>
              <td>Female</td>
              <td>1266 (54.7)</td>
              <td>10,943 (47.3)</td>
              <td>12,209 (48)</td>
              <td/>
            </tr>
            <tr valign="top">
              <td>
                <break/>
              </td>
              <td>Male</td>
              <td>1048 (45.3)</td>
              <td>12,186 (52.7)</td>
              <td>13,234 (52)</td>
              <td/>
            </tr>
            <tr valign="top">
              <td colspan="2">
                <bold>Race or ethnicity, n (%)</bold>
              </td>
              <td/>
              <td/>
              <td/>
              <td>&#60;.001</td>
            </tr>
            <tr valign="top">
              <td>
                <break/>
              </td>
              <td>Non-Hispanic White</td>
              <td>870 (37.6)</td>
              <td>9795 (42.3)</td>
              <td>10,665 (41.9)</td>
              <td/>
            </tr>
            <tr valign="top">
              <td>
                <break/>
              </td>
              <td>Hispanic</td>
              <td>834 (36)</td>
              <td>7199 (31.1)</td>
              <td>8033 (31.6)</td>
              <td/>
            </tr>
            <tr valign="top">
              <td>
                <break/>
              </td>
              <td>Non-Hispanic Black or African American</td>
              <td>213 (9.2)</td>
              <td>2171 (9.4)</td>
              <td>2384 (9.4)</td>
              <td/>
            </tr>
            <tr valign="top">
              <td>
                <break/>
              </td>
              <td>Non-Hispanic Asian, American Indian, or Alaskan Native</td>
              <td>205 (8.9)</td>
              <td>1949 (8.4)</td>
              <td>2154 (8.5)</td>
              <td/>
            </tr>
            <tr valign="top">
              <td>
                <break/>
              </td>
              <td>Other<sup>a</sup> or unknown</td>
              <td>192 (8.3)</td>
              <td>2015 (8.7)</td>
              <td>2207 (8.7)</td>
              <td/>
            </tr>
            <tr valign="top">
              <td colspan="2">
                <bold>PCP<sup>b</sup>, n (%)</bold>
              </td>
              <td/>
              <td/>
              <td/>
              <td>.75</td>
            </tr>
            <tr valign="top">
              <td>
                <break/>
              </td>
              <td>UCSD<sup>c</sup> PCP</td>
              <td>644 (27.8)</td>
              <td>6509 (28.1)</td>
              <td>7153 (28.1)</td>
              <td/>
            </tr>
            <tr valign="top">
              <td>
                <break/>
              </td>
              <td>Non-UCSD PCP</td>
              <td>1670 (72.2)</td>
              <td>16,620 (71.9)</td>
              <td>18,290 (71.9)</td>
              <td/>
            </tr>
            <tr valign="top">
              <td colspan="2">
                <bold>LACE+ score range, n (%)</bold>
              </td>
              <td/>
              <td/>
              <td/>
              <td>&#60;.001</td>
            </tr>
            <tr valign="top">
              <td>
                <break/>
              </td>
              <td>&#60;50</td>
              <td>79 (3.4)</td>
              <td>2321 (10)</td>
              <td>2400 (9.4)</td>
              <td/>
            </tr>
            <tr valign="top">
              <td>
                <break/>
              </td>
              <td>50-70</td>
              <td>113 (65.4)</td>
              <td>9152 (39.6)</td>
              <td>10,665 (41.9)</td>
              <td/>
            </tr>
            <tr valign="top">
              <td>
                <break/>
              </td>
              <td>&#62;70</td>
              <td>722 (31.2)</td>
              <td>11,656 (50.4)</td>
              <td>12,378 (48.6)</td>
              <td/>
            </tr>
          </tbody>
        </table>
        <table-wrap-foot>
          <fn id="table1fn1">
            <p><sup>a</sup>Self-reported “other” race or ethnicity or missing data.</p>
          </fn>
          <fn id="table1fn2">
            <p><sup>b</sup>PCP: primary care provider.</p>
          </fn>
          <fn id="table1fn3">
            <p><sup>c</sup>UCSD: University of California San Diego.</p>
          </fn>
        </table-wrap-foot>
      </table-wrap>
      <p>The overall 30-day readmission rate for patients seen in the VToC clinic was 14.9% (344/2314) compared to 20.1% (4659/23,129) in the benchmark group (<xref ref-type="table" rid="table1">Table 1</xref>; <italic>P</italic>&#60;.001). In the regression model, the absence of a VToC clinic was independently associated with increased odds of readmission (odds ratio 1.37; 95% CI 1.21-1.54; <italic>P</italic>&#60;.001). In the multivariable regression analysis, younger age, female sex, non-Hispanic Asian race or ethnicity, higher LACE+ scores, and non-participation in the VToC program were each independently associated with increased odds of hospital readmission." should be changed to "In the multivariable regression analysis, younger age, female sex, Hispanic and Non Hispanic Black/African American race or ethnicity, higher LACE+ scores, and nonparticipation in the VToC program were each independently associated with increased odds of hospital readmission. This analysis is available in <xref ref-type="supplementary-material" rid="app1">Multimedia Appendix 1</xref>. Decile matching was performed to account for the difference in distribution of LACE+ in the VToC and non-VToC groups. Analysis of LACE+ decile groups revealed that the impact of readmission reduction was most prominent among patients with LACE+ scores ranging between 50-75; however, across most groups VTOC performed better than non-VToC (<xref rid="figure1" ref-type="fig">Figure 1</xref>).</p>
      <fig id="figure1" position="float">
        <label>Figure 1</label>
        <caption>
          <p>This figure presents 30-day readmission rates for patients who received the virtual transitions of care (VToC) intervention (dark bars) versus those who did not (light bars), stratified by LACE+ score decile groups. The x-axis represents different LACE+ decile groups, while the y-axis shows readmission rates as percentages. Error bars are included for each proportion and represent the difference between the point estimate (proportion) and upper or lower CI. The targeted population for this intervention was patients with LACE+ scores between 50 and 75. Deciles outside this range are included for completeness. Across most LACE+ decile ranges, the VToC group consistently showed lower readmission rates compared to the non-VToC group.</p>
        </caption>
        <graphic xlink:href="medinform_v13i1e73495_fig1.png" alt-version="no" mimetype="image" position="float" xlink:type="simple"/>
      </fig>
    </sec>
    <sec sec-type="discussion">
      <title>Discussion</title>
      <p>Here we present a hospitalist-led postdischarge virtual clinic aimed at improving transitions of care for patients. For patients at moderate risk, a VToC visit was associated with a significantly lower rate of readmission. Notably, our intervention group had a higher proportion of female and Hispanic patients, both of which were associated with increased odds of readmission in regression analyses.</p>
      <p>This observational study is subject to selection bias, as clinic attendance could be influenced by patient-specific factors that influence readmission. Approximately 13% of patients referred to the VToC were not reached, which may introduce additional bias, as these individuals may differ in ways that influence outcomes. While we did not capture detailed data on patient acceptance, we addressed this limitation by matching the comparator group on readmission risk to reduce confounding. However, the stratified analysis according to the LACE+ index provides strong evidence in support of the impact of the program, and the positive impact observed is consistent with broader evidence that timely postdischarge access reduces readmission risk. VToC clinics address a critical gap in the care continuum while also providing the inherent benefits of telemedicine [<xref ref-type="bibr" rid="ref6">6</xref>,<xref ref-type="bibr" rid="ref8">8</xref>].</p>
      <p>Results from this initiative are promising for the feasibility of telemedicine-based transitional care programs to promote the quadruple aim of improving population health, enhancing the care experience, reducing cost, and advancing care equity [<xref ref-type="bibr" rid="ref9">9</xref>].</p>
    </sec>
  </body>
  <back>
    <app-group>
      <supplementary-material id="app1">
        <label>Multimedia Appendix 1</label>
        <p>Supplementary data.</p>
        <media xlink:href="medinform_v13i1e73495_app1.xlsx" xlink:title="XLSX File  (Microsoft Excel File), 531 KB"/>
      </supplementary-material>
    </app-group>
    <glossary>
      <title>Abbreviations</title>
      <def-list>
        <def-item>
          <term id="abb1">PCP</term>
          <def>
            <p>primary care provider</p>
          </def>
        </def-item>
        <def-item>
          <term id="abb2">VToC</term>
          <def>
            <p>virtual transitions of care</p>
          </def>
        </def-item>
      </def-list>
    </glossary>
    <ack>
      <p>Thank you to Eric Lundin for project management support. Thank you to the hospitalist physicians including Drs Maryann Ally, Diana Childers, Catherine Firestein, Jonathan McIntyre, David Reis, Reid Sasaki, Jennifer Quartarolo, Supraja Thota, and Anne Xing and to Richard Nguyen for information support services. Special thanks to Trina Huynh for pharmacist support and leadership, and to Eileen Hailey and Nancy Renshaw for collaborative operational leadership from the Department of Population Health.</p>
    </ack>
    <notes>
      <sec>
        <title>Data Availability</title>
        <p>All data generated or analyzed during this study are included in this published article and its supplementary information files.</p>
      </sec>
    </notes>
    <fn-group>
      <fn fn-type="con">
        <p>SFH served as the lead author and was responsible for project design, manuscript writing, and overall coordination. MK contributed as a hospitalist provider for the clinic and was involved in manuscript writing and data analysis. EC provided data analytic support and assisted in interpreting the results. PM offered executive sponsorship, strategic guidance, and support for project scaling and resourcing. CV participated as a member of the steering committee and provided advisory input and quality oversight in his role as Chief Quality Officer of the University of California, San Diego Health. JB contributed to the design and implementation of the referral order mechanism and automation processes. CAL provided executive sponsorship and played a key role in program design, implementation, scaling, and dissemination, as well as supporting manuscript writing, editing, and analytic advising.</p>
      </fn>
      <fn fn-type="conflict">
        <p>None declared.</p>
      </fn>
    </fn-group>
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