<?xml version="1.0" encoding="UTF-8"?>
<!DOCTYPE article PUBLIC "-//NLM//DTD Journal Publishing DTD v2.0 20040830//EN" "http://dtd.nlm.nih.gov/publishing/2.0/journalpublishing.dtd">
<?covid-19-tdm?>
<article xmlns:xlink="http://www.w3.org/1999/xlink" article-type="research-article" dtd-version="2.0">
  <front>
    <journal-meta>
      <journal-id journal-id-type="publisher-id">JMI</journal-id>
      <journal-id journal-id-type="nlm-ta">JMIR Med Inform</journal-id>
      <journal-title>JMIR Medical Informatics</journal-title>
      <issn pub-type="epub">2291-9694</issn>
      <publisher>
        <publisher-name>JMIR Publications</publisher-name>
        <publisher-loc>Toronto, Canada</publisher-loc>
      </publisher>
    </journal-meta>
    <article-meta>
      <article-id pub-id-type="publisher-id">v9i2e25183</article-id>
      <article-id pub-id-type="pmid">33449905</article-id>
      <article-id pub-id-type="doi">10.2196/25183</article-id>
      <article-categories>
        <subj-group subj-group-type="heading">
          <subject>Original Paper</subject>
        </subj-group>
        <subj-group subj-group-type="article-type">
          <subject>Original Paper</subject>
        </subj-group>
      </article-categories>
      <title-group>
        <article-title>Driving Digital Transformation During a Pandemic: Case Study of Virtual Collaboration in a German Hospital</article-title>
      </title-group>
      <contrib-group>
        <contrib contrib-type="editor">
          <name>
            <surname>Eysenbach</surname>
            <given-names>Gunther</given-names>
          </name>
        </contrib>
      </contrib-group>
      <contrib-group>
        <contrib contrib-type="reviewer">
          <name>
            <surname>Sun</surname>
            <given-names>Pengfei</given-names>
          </name>
        </contrib>
        <contrib contrib-type="reviewer">
          <name>
            <surname>Kaufhold</surname>
            <given-names>Marc-André</given-names>
          </name>
        </contrib>
      </contrib-group>
      <contrib-group>
        <contrib id="contrib1" contrib-type="author" corresp="yes" equal-contrib="yes">
          <name name-style="western">
            <surname>Frick</surname>
            <given-names>Nicholas R J</given-names>
          </name>
          <degrees>BSc, MSc</degrees>
          <xref rid="aff1" ref-type="aff">1</xref>
          <address>
            <institution>Department of IT-Strategy</institution>
            <institution>MAINGAU Energie GmbH</institution>
            <addr-line>Ringstraße 4</addr-line>
            <addr-line>Obertshausen, 63179</addr-line>
            <country>Germany</country>
            <phone>49 1711904454</phone>
            <email>nicholas.frick@maingau-energie.de</email>
          </address>
          <ext-link ext-link-type="orcid">https://orcid.org/0000-0002-9075-4433</ext-link>
        </contrib>
        <contrib id="contrib2" contrib-type="author" equal-contrib="yes">
          <name name-style="western">
            <surname>Möllmann</surname>
            <given-names>Henriette L</given-names>
          </name>
          <degrees>Dr med, Dr med dent</degrees>
          <xref rid="aff2" ref-type="aff">2</xref>
          <ext-link ext-link-type="orcid">https://orcid.org/0000-0002-1040-8814</ext-link>
        </contrib>
        <contrib id="contrib3" contrib-type="author">
          <name name-style="western">
            <surname>Mirbabaie</surname>
            <given-names>Milad</given-names>
          </name>
          <degrees>Prof Dr rer pol</degrees>
          <xref rid="aff3" ref-type="aff">3</xref>
          <ext-link ext-link-type="orcid">https://orcid.org/0000-0002-9455-5773</ext-link>
        </contrib>
        <contrib id="contrib4" contrib-type="author">
          <name name-style="western">
            <surname>Stieglitz</surname>
            <given-names>Stefan</given-names>
          </name>
          <degrees>Prof Dr rer pol</degrees>
          <xref rid="aff4" ref-type="aff">4</xref>
          <ext-link ext-link-type="orcid">https://orcid.org/0000-0002-4366-1840</ext-link>
        </contrib>
      </contrib-group>
      <aff id="aff1">
        <label>1</label>
        <institution>Department of IT-Strategy</institution>
        <institution>MAINGAU Energie GmbH</institution>
        <addr-line>Obertshausen</addr-line>
        <country>Germany</country>
      </aff>
      <aff id="aff2">
        <label>2</label>
        <institution>Department of Oral-, Maxillo- and Plastic Facial Surgery</institution>
        <institution>Heinrich-Heine-University Duesseldorf</institution>
        <addr-line>Duesseldorf</addr-line>
        <country>Germany</country>
      </aff>
      <aff id="aff3">
        <label>3</label>
        <institution>Department of Business Studies and Economics</institution>
        <institution>University of Bremen</institution>
        <addr-line>Bremen</addr-line>
        <country>Germany</country>
      </aff>
      <aff id="aff4">
        <label>4</label>
        <institution>Professional Communication in Electronic Media/Social Media</institution>
        <institution>University of Duisburg-Essen</institution>
        <addr-line>Duisburg</addr-line>
        <country>Germany</country>
      </aff>
      <author-notes>
        <corresp>Corresponding Author: Nicholas R J Frick <email>nicholas.frick@maingau-energie.de</email></corresp>
      </author-notes>
      <pub-date pub-type="collection">
        <month>2</month>
        <year>2021</year>
      </pub-date>
      <pub-date pub-type="epub">
        <day>1</day>
        <month>2</month>
        <year>2021</year>
      </pub-date>
      <volume>9</volume>
      <issue>2</issue>
      <elocation-id>e25183</elocation-id>
      <history>
        <date date-type="received">
          <day>21</day>
          <month>10</month>
          <year>2020</year>
        </date>
        <date date-type="rev-request">
          <day>21</day>
          <month>12</month>
          <year>2020</year>
        </date>
        <date date-type="rev-recd">
          <day>9</day>
          <month>1</month>
          <year>2021</year>
        </date>
        <date date-type="accepted">
          <day>14</day>
          <month>1</month>
          <year>2021</year>
        </date>
      </history>
      <copyright-statement>©Nicholas R J Frick, Henriette L Möllmann, Milad Mirbabaie, Stefan Stieglitz. Originally published in JMIR Medical Informatics (http://medinform.jmir.org), 01.02.2021.</copyright-statement>
      <copyright-year>2021</copyright-year>
      <license license-type="open-access" xlink:href="https://creativecommons.org/licenses/by/4.0/">
        <p>This is an open-access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work, first published in JMIR Medical Informatics, is properly cited. The complete bibliographic information, a link to the original publication on http://medinform.jmir.org/, as well as this copyright and license information must be included.</p>
      </license>
      <self-uri xlink:href="https://medinform.jmir.org/2021/2/e25183" xlink:type="simple"/>
      <abstract>
        <sec sec-type="background">
          <title>Background</title>
          <p>The COVID-19 pandemic has not only changed the private lives of millions of people but has significantly affected the collaboration of medical specialists throughout health care systems worldwide. Hospitals are making changes to their regular operations to slow the spread of SARS-CoV-2 while ensuring the treatment of emergency patients. These substantial changes affect the typical work setting of clinicians and require the implementation of organizational arrangements.</p>
        </sec>
        <sec sec-type="objective">
          <title>Objective</title>
          <p>In this study, we aim to increase our understanding of how digital transformation drives virtual collaboration among clinicians in hospitals in times of crisis, such as the COVID-19 pandemic.</p>
        </sec>
        <sec sec-type="methods">
          <title>Methods</title>
          <p>We present the lessons learned from an exploratory case study in which we observed the introduction of an information technology (IT) system for enhancing collaboration among clinicians in a German hospital. The results are based on 16 semistructured interviews with physicians from various departments and disciplines; the interviews were generalized to better understand and interpret the meaning of the statements.</p>
        </sec>
        <sec sec-type="results">
          <title>Results</title>
          <p>Three key lessons and recommendations explain how digital transformation ensures goal-driven collaboration among clinicians. First, we found that implementing a disruptive change requires alignment of the mindsets of the stakeholders. Second, IT-enabled collaboration presupposes behavioral rules that must be followed. Third, transforming antiquated processes demands a suitable technological infrastructure.</p>
        </sec>
        <sec sec-type="conclusions">
          <title>Conclusions</title>
          <p>Digital transformation is being driven by the COVID-19 pandemic. However, the rapid introduction of IT-enabled collaboration reveals grievances concerning the digital dissemination of medical information along the patient treatment path. To avoid being caught unprepared by future crises, digital transformation must be further driven to ensure collaboration, and the diagnostic and therapeutic process must be opened to disruptive strategies.</p>
        </sec>
      </abstract>
      <kwd-group>
        <kwd>digital transformation</kwd>
        <kwd>virtual collaboration</kwd>
        <kwd>digital health</kwd>
        <kwd>health care</kwd>
        <kwd>COVID-19</kwd>
        <kwd>pandemic</kwd>
        <kwd>hospital</kwd>
        <kwd>collaboration</kwd>
        <kwd>virtual heath</kwd>
        <kwd>crisis</kwd>
        <kwd>case study</kwd>
      </kwd-group>
    </article-meta>
  </front>
  <body>
    <sec sec-type="introduction">
      <title>Introduction</title>
      <p>The impact of COVID-19, the disease caused by SARS-CoV-2, has not only changed our lives and interactions as human beings but has had substantial consequences for health care systems worldwide [<xref ref-type="bibr" rid="ref1">1</xref>]. Above all, hospitals must slow the spread of SARS-CoV-2 and further ensure a certain level of daily routine to maintain regular care and treatment of emergency patients. In addition to changes to clinical routines [<xref ref-type="bibr" rid="ref2">2</xref>,<xref ref-type="bibr" rid="ref3">3</xref>], this process involves adjustments in the way that clinicians work together.</p>
      <p>Collaboration among hospital employees, particularly between physicians and interconnected medical departments, is essential for the overall diagnosis and treatment process [<xref ref-type="bibr" rid="ref4">4</xref>-<xref ref-type="bibr" rid="ref7">7</xref>]. Because the health care system is interdisciplinary in nature, goal-driven collaboration enhances the performance of services, quality of care, and patient outcomes [<xref ref-type="bibr" rid="ref8">8</xref>-<xref ref-type="bibr" rid="ref11">11</xref>]. Collaboration in hospitals can be defined as a professional alliance between health care specialists from multiple medical disciplines with diverse backgrounds and varying expertise, who jointly provide benefits for patients [<xref ref-type="bibr" rid="ref12">12</xref>,<xref ref-type="bibr" rid="ref13">13</xref>]. Although collaboration is considered to be a top priority in hospitals [<xref ref-type="bibr" rid="ref14">14</xref>], some common issues are frequently experienced by clinicians [<xref ref-type="bibr" rid="ref15">15</xref>]. Insufficient communication, including improper exchange of medical information, is a prevalent concern [<xref ref-type="bibr" rid="ref16">16</xref>]. Clinicians manage their tasks in isolation with a lack of mutual understanding, which prevents the sharing of knowledge across departmental boundaries and inhibits collaboration between disciplines [<xref ref-type="bibr" rid="ref17">17</xref>,<xref ref-type="bibr" rid="ref18">18</xref>]. Furthermore, hospitals operate in complex clinical infrastructures, with a wide range of information systems containing different medical information; these systems are disconnected from each other and operated by multiple professionals [<xref ref-type="bibr" rid="ref19">19</xref>,<xref ref-type="bibr" rid="ref20">20</xref>]. Consistent presentation of medical data is lacking, and the retrieval of information stored across diversified systems is a time-consuming procedure [<xref ref-type="bibr" rid="ref21">21</xref>,<xref ref-type="bibr" rid="ref22">22</xref>].</p>
      <p>In addition to existing collaborative challenges in hospitals [<xref ref-type="bibr" rid="ref15">15</xref>], clinicians are being confronted with issues emerging from the COVID-19 pandemic [<xref ref-type="bibr" rid="ref23">23</xref>]. Medical workers must not only examine individuals who are infected with the novel virus but must also respond to normal emergencies and patient cases. The required response involves substantial dedication and demands the implementation of diverse organizational arrangements as well as safety precautions [<xref ref-type="bibr" rid="ref24">24</xref>]. Changes in surgery include decreasing the number of elective procedures to gain more capacity for emergency interventions [<xref ref-type="bibr" rid="ref25">25</xref>]. Staff caring for patients with COVID-19 are separated from those caring for other patients, and postoperative visits are suspended and replaced by telephone calls to prevent in-hospital spread [<xref ref-type="bibr" rid="ref3">3</xref>]. Furthermore, clinics are divided into multiple teams to prevent quarantine of an entire department, thus providing patient care in the case of infection. The underlying objective of reducing interpersonal communication compensates for any shortfall and maintains clinical operations. However, due to these necessary adjustments, collaboration in hospitals has changed significantly and has rapidly shifted toward virtual environments. Clinicians have started exchanging information using social media or instant messaging, and meetings are increasingly being conducted using applicable and available technology [<xref ref-type="bibr" rid="ref3">3</xref>,<xref ref-type="bibr" rid="ref26">26</xref>].</p>
      <p>The integration of technologies into existing processes is a key component of the digital transformation [<xref ref-type="bibr" rid="ref27">27</xref>,<xref ref-type="bibr" rid="ref28">28</xref>] that improves cross-functional collaboration and coordination among individuals [<xref ref-type="bibr" rid="ref29">29</xref>,<xref ref-type="bibr" rid="ref30">30</xref>]. Digital transformation is defined as “a process that aims to improve an entity by triggering significant changes to its properties through combinations of information, computing, communication, and connectivity technologies” [<xref ref-type="bibr" rid="ref30">30</xref>]. Therefore, digital transformation addresses changes associated with the introduction of new information technology (IT) in current organizational structures [<xref ref-type="bibr" rid="ref31">31</xref>,<xref ref-type="bibr" rid="ref32">32</xref>]. Because digital transformation is concerned with improving collaboration between individuals [<xref ref-type="bibr" rid="ref30">30</xref>], it is closely linked to the computer-supported cooperative work (CSCW) research stream. CSCW determines how technology can increase group communication and work efforts [<xref ref-type="bibr" rid="ref33">33</xref>]; thus, it is a vital component for understanding the dynamics of digital transformation [<xref ref-type="bibr" rid="ref34">34</xref>] and associated changes of collaboration in practice [<xref ref-type="bibr" rid="ref30">30</xref>].</p>
      <p>In health care, digital transformation deliberately seeks to answer the question of how the quality of care and its related services can be improved with technology, as both rely on accurate, relevant, integrated and quickly accessible information [<xref ref-type="bibr" rid="ref35">35</xref>,<xref ref-type="bibr" rid="ref36">36</xref>]. For example, recent research examined how processes and digital infrastructure must be aligned to drive IT-enabled innovations [<xref ref-type="bibr" rid="ref37">37</xref>] and whether advanced technologies, such as the Internet of Things (IoT) and artificial intelligence (AI) [<xref ref-type="bibr" rid="ref38">38</xref>,<xref ref-type="bibr" rid="ref39">39</xref>], can be integrated to empower caregivers to make evidence-based clinical decisions [<xref ref-type="bibr" rid="ref28">28</xref>]. Extant research is further concerned with the potential of health information technology (HIT) to improve patient outcomes while reducing costs [<xref ref-type="bibr" rid="ref40">40</xref>]. One example of HIT that is fundamentally transforming health services is electronic health records (EHRs), which digitally capture patients’ retrospective, concurrent, and prospective information to guide medical treatment [<xref ref-type="bibr" rid="ref41">41</xref>]. In this realm, scholars are exploring how technology is creating smart hospitals [<xref ref-type="bibr" rid="ref42">42</xref>], that is, clinical environments with optimized and automated processes based on technological advancements and intelligent facilities to introduce new capabilities and provide an ideal surrounding for patients [<xref ref-type="bibr" rid="ref42">42</xref>-<xref ref-type="bibr" rid="ref44">44</xref>].</p>
      <p>However, the increasing application of technology also serves as a basis for enhancing information exchange and collaboration in hospitals [<xref ref-type="bibr" rid="ref15">15</xref>,<xref ref-type="bibr" rid="ref45">45</xref>-<xref ref-type="bibr" rid="ref47">47</xref>]. Collaborative visioning promotes joint decision-making and helps to overcome related issues frequently experienced by clinicians [<xref ref-type="bibr" rid="ref48">48</xref>]. Communication is improved as information is presented transparently for involved experts. For example, central platforms coordinate the diffusion of reports and information exchange among participants [<xref ref-type="bibr" rid="ref29">29</xref>,<xref ref-type="bibr" rid="ref49">49</xref>]. The free transfer of medical information across departmental boundaries further establishes a closer alignment with collaborators from other departments, which dissolves silo thinking [<xref ref-type="bibr" rid="ref50">50</xref>,<xref ref-type="bibr" rid="ref51">51</xref>]. In addition, the introduction of standards simplifies complex clinical infrastructures and contributes to a feasible exchange of medical data between detached HIT systems; it also assists clinicians in gathering information more quickly [<xref ref-type="bibr" rid="ref28">28</xref>].</p>
      <p>In summary, the technological capacity for enhancing information exchange and collaboration focusing on patient outcomes is widely available [<xref ref-type="bibr" rid="ref45">45</xref>-<xref ref-type="bibr" rid="ref47">47</xref>]. Digital transformation and associated technologies are essential to facilitate the exchange of information among clinicians across organizational boundaries, as new forms of collaborative work drive operational performance [<xref ref-type="bibr" rid="ref15">15</xref>,<xref ref-type="bibr" rid="ref30">30</xref>,<xref ref-type="bibr" rid="ref31">31</xref>]. However, in their complex clinical environments, hospitals traditionally struggle to adopt new technologies [<xref ref-type="bibr" rid="ref19">19</xref>,<xref ref-type="bibr" rid="ref20">20</xref>], especially when aligning IT-enabled transformations with existing infrastructure [<xref ref-type="bibr" rid="ref52">52</xref>]. Agarwal et al [<xref ref-type="bibr" rid="ref17">17</xref>] stated that “an IT-enabled transformation of health care is just beginning, and it cannot happen too fast.” However, the present situation of the COVID-19 pandemic is confronting hospitals with the urgent need to identify valid solutions while maintaining a sufficient level of collaboration and complying with the legal requirements of social distancing. Radical actions and restrictions are unavoidable for hospitals; however, they involve profound implications. Habitual collaboration is altered instantly, with no or only partial consideration of possible influencing factors such as available resources or security and data protection. Furthermore, the entire process of integrating technologies is likely to be faster during a crisis than under normal conditions, as people are conducting sense-making on a different level [<xref ref-type="bibr" rid="ref53">53</xref>,<xref ref-type="bibr" rid="ref54">54</xref>]. Disruptive technologies that are being applied to combat the COVID-19 pandemic are replacing traditional communication in health care teams [<xref ref-type="bibr" rid="ref55">55</xref>] and are fundamental for sustained collaboration in hospitals. The ongoing pandemic is therefore creating a pressing need to rethink collaboration between clinicians; however, research on how digital transformation advocates collaboration in hospitals during a crisis is still lacking. We argue that this topic is of great interest to researchers and practitioners because virtual collaboration in hospitals will increase even further in the near future and persist for a long time. Thus, our research is guided by the following question: <italic>How is digital transformation driving collaboration among clinicians in a time of crisis?</italic></p>
      <p>We report the unique findings of an exploratory case study of a German hospital, in which we observed the introduction of an IT system to enhance collaboration among physicians during the COVID-19 pandemic. Our results are based and on 16 generalized semistructured interviews with physicians from various departments. We explain how clinicians worked together before the ongoing crisis, what has changed as a result of the pandemic, how the introduction of an IT system ensured effective collaboration, and how the digital transformation should continue to transform hospital operations.</p>
      <p>We aim to increase our understanding of how digital transformation can improve collaboration among clinicians in the subject hospital and other hospitals. Moreover, it will demonstrate how the proposed IT improvements can ensure accurate, safe, and effective patient care not just for future crises but for daily operations. Researchers will be able to use our key lessons to understand the difference between a regular installation and one made out of necessity, along with their advantages and disadvantages. Practitioners will be able to understand how our recommendations help to ensure goal-driven collaboration and how hospitals can benefit from them. We hope to guide decision makers who want to introduce IT to improve collaboration between clinicians and stimulate additional research in this important field by expanding the body of knowledge.</p>
    </sec>
    <sec sec-type="methods">
      <title>Methods</title>
      <p>The German health care system is a highly developed sector in which the health of the population and life expectancy has continuously risen [<xref ref-type="bibr" rid="ref56">56</xref>]. In the fight against SARS-CoV-2, wide-ranging countermeasures were backed by the German government and introduced at an early stage. A crisis taskforce was convened on February 27, 2020, and the first nationwide restrictions on public access were adopted on March 22 [<xref ref-type="bibr" rid="ref57">57</xref>]. There is no evidence that the system was overburdened, as only 60% of the total of 33,051 intensive care beds were in use [<xref ref-type="bibr" rid="ref58">58</xref>]. However, the new restrictions undoubtedly influenced hospitals and the ways in which their employees interacted with each other. To determine how collaboration between clinicians changed during the COVID-19 pandemic, we observed the introduction of an IT system at a large German hospital during the period from March 24 to April 24, 2020.</p>
      <p>The hospital decided to introduce and provide Microsoft Teams (Microsoft Corporation) throughout the clinic. It was necessary to maintain collaboration between physicians, including those who were working from home, during the pandemic. Furthermore, restricted personal contact was needed to slow the spread of the virus. Microsoft Teams is a collaboration platform with features such as chatting, video calls, and file sharing. It can be used by many devices, such as personal computers, notebooks, tablets, and smartphones [<xref ref-type="bibr" rid="ref59">59</xref>]. In response to the COVID-19 outbreak, Microsoft decided to offer the Teams software for free to help individuals stay connected [<xref ref-type="bibr" rid="ref60">60</xref>].</p>
      <p>Additionally, several organizational changes were initiated by the hospital. The departments were split into two different teams and worked in a weekly rotation to ensure that if one team was contaminated with the virus, the second team would be able to continue working and providing appropriate patient care. Furthermore, all elective procedures were reduced to a minimum, and only urgent surgeries were performed. However, the most crucial action was the minimization of any face-to-face exchanges between clinicians.</p>
      <p>As presented in <xref rid="figure1" ref-type="fig">Figure 1</xref>, the case study preceded the implementation and test phase conducted by the hospital’s IT department. The decision to implement the corresponding emergency concept, including the rollout of Microsoft Teams, was made on March 17 by the hospital management. On March 24, the software was installed on the employees’ computers. Installation was followed by a week-long test phase during which additional hardware, such as cameras, microphones, and speakers, was installed. Because Microsoft Teams had not been used in the clinic before, clinicians had little or no knowledge of how to use the system. We provided advice and tips exclusively remotely, as visits to the hospital were forbidden to prevent the virus from infecting other patients and spreading. Finally, the first formal meeting and the official start of our support took place on April 1.</p>
      <p>After the new system was introduced, we conducted 16 semistructured interviews with physicians. The interviews were designed to provide “questioning guided by identified themes in a consistent and systematic manner” [<xref ref-type="bibr" rid="ref61">61</xref>]. We developed a guide containing relevant questions in advance. Our goal was to make the guidelines as comprehensive as possible because physicians are typically available for a limited time, especially during a crisis. The guide was divided into chapters, with initial questions and subsequent follow-up questions (see <xref ref-type="table" rid="table1">Table 1</xref>).</p>
      <p>Because we were interested in the meaning of the experts’ substantive statements and not in their linguistic habitus or expressions, which are not necessary for understanding the context, nor in their physical gestures or facial expressions, we decided to paraphrase the interviews instead of conducting verbatim transcriptions. The analysis of the interviews was based on the recommendations in the qualitative assessment of content analysis by Schilling [<xref ref-type="bibr" rid="ref28">28</xref>]. Paraphrasing the data reduced the volume by removing unnecessary words to form short, concise sentences. We listened carefully to the interview recordings and paraphrased the content of the physicians’ statements. Next, we generalized and reduced the content to better understand and interpret the meaning of the statements [<xref ref-type="bibr" rid="ref62">62</xref>]. The subsequent categorization was guided by the recommendations of Mayring [<xref ref-type="bibr" rid="ref29">29</xref>] for an organization of data derived from the material itself. This inductive category formation approach described the data without predefined criteria, leading to an unbiased “understanding of the material in terms of the material” [<xref ref-type="bibr" rid="ref63">63</xref>].</p>
      <p>The physicians were aged between 25 and 42 years (mean 32.2 years, SD 4.4), with 9 female and 7 male experts, and their tenures ranged from 0.5-17 years (mean 4.3 years, SD 4.4). Of the participants, 3 were senior physicians and 13 were resident physicians from 3 different clinics. The interviews were conducted using Microsoft Teams, with which the physicians were by then familiar. The interviews lasted between 9:04 and 28:25 minutes and were recorded, analyzed, and deleted once the evaluation was finished to protect the privacy of the participants. An overview of our sample is outlined in <xref ref-type="table" rid="table2">Table 2</xref>. The results yielded novel insights on how physicians collaborate with the assistance of technology during a pandemic. They broadened our view on collaboration among physicians in hospitals.</p>
      <fig id="figure1" position="float">
        <label>Figure 1</label>
        <caption>
          <p>Process of the introduction of Microsoft Teams in the hospital.</p>
        </caption>
        <graphic xlink:href="medinform_v9i2e25183_fig1.png" alt-version="no" mimetype="image" position="float" xlink:type="simple"/>
      </fig>
      <table-wrap position="float" id="table1">
        <label>Table 1</label>
        <caption>
          <p>Interview guideline.</p>
        </caption>
        <table width="1000" cellpadding="5" cellspacing="0" border="1" rules="groups" frame="hsides">
          <col width="300"/>
          <col width="350"/>
          <col width="350"/>
          <thead>
            <tr valign="top">
              <td>Chapter</td>
              <td>Content or questions</td>
              <td>Follow-up questions</td>
            </tr>
          </thead>
          <tbody>
            <tr valign="top">
              <td>Before the interview</td>
              <td>Introduction and summary of the purpose of this research, including an explanation of the interviewee’s rights and verbal consent for the interview to be recorded</td>
              <td>None</td>
            </tr>
            <tr valign="top">
              <td>Demographic data</td>
              <td>1. What is your name and how old are you?<break/>2. What is your current position at the hospital?<break/>3. What tasks does your current position involve?</td>
              <td>None</td>
            </tr>
            <tr valign="top">
              <td>The conditions before the crisis/pandemic</td>
              <td>4. How was the collaboration with each other (with your colleagues) before the crisis/pandemic?</td>
              <td>a. With whom did you primarily collaborate?<break/>b. How did you collaborate?<break/>c. Which IT<sup>a</sup> systems did you use for this purpose?</td>
            </tr>
            <tr valign="top">
              <td/>
              <td>5. Where have been problems in the collaboration?</td>
              <td>None</td>
            </tr>
            <tr valign="top">
              <td>The conditions during the crisis/pandemic</td>
              <td>6. What was the goal of introducing Microsoft Teams in your hospital or clinic during the crisis/pandemic?</td>
              <td>None</td>
            </tr>
            <tr valign="top">
              <td/>
              <td>7. How has the introduction changed collaboration during the crisis/pandemic?</td>
              <td>a. With whom do you collaborate?<break/>b. How has your collaboration behavior changed?<break/>c. What types of devices do you use for collaborating?<break/>d. Have your tasks or responsibilities changed?<break/>e. Has your culture within the clinic changed? Do you treat each other differently?</td>
            </tr>
            <tr valign="top">
              <td/>
              <td>8. What advantages have resulted from the introduction in your collaboration?</td>
              <td>a. Benefits for the team and/or individuals?<break/>b. Benefits for other hospitals employees?<break/>c. Benefits for patients?</td>
            </tr>
            <tr valign="top">
              <td/>
              <td>9. What disadvantages have arisen from the introduction in your collaboration?</td>
              <td>a. Surveillance?<break/>b. Data protection?<break/>c. Ethical issues or legal questions?</td>
            </tr>
            <tr valign="top">
              <td/>
              <td>10. What challenges have been identified during the introduction?</td>
              <td>a. Technical problems?<break/>b. Acceptance, handling, resistance?</td>
            </tr>
            <tr valign="top">
              <td>The conditions after the crisis/pandemic</td>
              <td>11. Would you like to receive further technical support for collaboration?</td>
              <td>a. Further use of Microsoft Teams?</td>
            </tr>
            <tr valign="top">
              <td/>
              <td>12. In which other areas would you like to get more support?</td>
              <td>a. Artificial intelligence?<break/>b. Intelligent systems?</td>
            </tr>
            <tr valign="top">
              <td/>
              <td>13. What recommendations would you give other hospitals or their staff to improve collaboration in their clinic?</td>
              <td>None</td>
            </tr>
            <tr valign="top">
              <td>After the interview</td>
              <td>Conclusion of the interview and the possibility for the expert to ask further questions or give closing remarks</td>
              <td>None</td>
            </tr>
          </tbody>
        </table>
        <table-wrap-foot>
          <fn id="table1fn1">
            <p><sup>a</sup>IT: information technology.</p>
          </fn>
        </table-wrap-foot>
      </table-wrap>
      <table-wrap position="float" id="table2">
        <label>Table 2</label>
        <caption>
          <p>Sample overview of the expert interviews.</p>
        </caption>
        <table width="1000" cellpadding="5" cellspacing="0" border="1" rules="groups" frame="hsides">
          <col width="100"/>
          <col width="100"/>
          <col width="100"/>
          <col width="150"/>
          <col width="150"/>
          <col width="150"/>
          <col width="250"/>
          <thead>
            <tr valign="top">
              <td>Number</td>
              <td>Age</td>
              <td>Gender</td>
              <td>Tenure (years)</td>
              <td>Position</td>
              <td>Clinic</td>
              <td>Length (minutes:seconds)</td>
            </tr>
          </thead>
          <tbody>
            <tr valign="top">
              <td>E1</td>
              <td>31</td>
              <td>Female</td>
              <td>1.5</td>
              <td>Resident physician</td>
              <td>Craniomaxillofacial surgery</td>
              <td>28:25</td>
            </tr>
            <tr valign="top">
              <td>E2</td>
              <td>33</td>
              <td>Female</td>
              <td>0.5</td>
              <td>Resident physician</td>
              <td>Craniomaxillofacial surgery</td>
              <td>19:21</td>
            </tr>
            <tr valign="top">
              <td>E3</td>
              <td>42</td>
              <td>Male</td>
              <td>17</td>
              <td>Senior physician</td>
              <td>Craniomaxillofacial surgery</td>
              <td>10:05</td>
            </tr>
            <tr valign="top">
              <td>E4</td>
              <td>32</td>
              <td>Male</td>
              <td>5</td>
              <td>Resident physician</td>
              <td>Craniomaxillofacial surgery</td>
              <td>17:31</td>
            </tr>
            <tr valign="top">
              <td>E5</td>
              <td>26</td>
              <td>Male</td>
              <td>0.75</td>
              <td>Resident physician</td>
              <td>Orthopedics and trauma surgery</td>
              <td>12:36</td>
            </tr>
            <tr valign="top">
              <td>E6</td>
              <td>34</td>
              <td>Female</td>
              <td>6</td>
              <td>Resident physician</td>
              <td>Craniomaxillofacial surgery</td>
              <td>09:04</td>
            </tr>
            <tr valign="top">
              <td>E7</td>
              <td>25</td>
              <td>Female</td>
              <td>0.3</td>
              <td>Resident physician</td>
              <td>Otorhinolaryngology</td>
              <td>10:57</td>
            </tr>
            <tr valign="top">
              <td>E8</td>
              <td>33</td>
              <td>Female</td>
              <td>1</td>
              <td>Resident physician</td>
              <td>Otorhinolaryngology</td>
              <td>09:34</td>
            </tr>
            <tr valign="top">
              <td>E9</td>
              <td>29</td>
              <td>Male</td>
              <td>2</td>
              <td>Resident physician</td>
              <td>Orthopedics and trauma surgery</td>
              <td>14:41</td>
            </tr>
            <tr valign="top">
              <td>E10</td>
              <td>28</td>
              <td>Female</td>
              <td>2.5</td>
              <td>Resident physician</td>
              <td>Orthopedics and trauma surgery</td>
              <td>14:41</td>
            </tr>
            <tr valign="top">
              <td>E11</td>
              <td>37</td>
              <td>Male</td>
              <td>7</td>
              <td>Senior physician</td>
              <td>Craniomaxillofacial surgery</td>
              <td>16:33</td>
            </tr>
            <tr valign="top">
              <td>E12</td>
              <td>38</td>
              <td>Female</td>
              <td>11</td>
              <td>Senior physician</td>
              <td>Craniomaxillofacial surgery</td>
              <td>14:40</td>
            </tr>
            <tr valign="top">
              <td>E13</td>
              <td>29</td>
              <td>Female</td>
              <td>2.5</td>
              <td>Resident physician</td>
              <td>Orthopedics and trauma surgery</td>
              <td>14:00</td>
            </tr>
            <tr valign="top">
              <td>E14</td>
              <td>32</td>
              <td>Female</td>
              <td>3.5</td>
              <td>Resident physician</td>
              <td>Otorhinolaryngology</td>
              <td>13:38</td>
            </tr>
            <tr valign="top">
              <td>E15</td>
              <td>31</td>
              <td>Male</td>
              <td>3.5</td>
              <td>Resident physician</td>
              <td>Otorhinolaryngology</td>
              <td>22:13</td>
            </tr>
            <tr valign="top">
              <td>E16</td>
              <td>36</td>
              <td>Male</td>
              <td>4</td>
              <td>Resident physician</td>
              <td>Orthopedics and trauma surgery</td>
              <td>15:17</td>
            </tr>
          </tbody>
        </table>
      </table-wrap>
    </sec>
    <sec sec-type="results">
      <title>Results</title>
      <p>This section describes the level of collaboration between clinicians before the crisis, what has changed because of the pandemic, and how it should be organized in the future. Excerpts from the German interviews have been translated into English for the reader’s convenience. For the purpose of anonymization, the numbering of the interviewees does not correspond to the order of the interviewees as depicted in <xref ref-type="table" rid="table2">Table 2</xref>.</p>
      <p><xref rid="figure2" ref-type="fig">Figure 2</xref> summarizes the results.</p>
      <fig id="figure2" position="float">
        <label>Figure 2</label>
        <caption>
          <p>Summary of case study results.</p>
        </caption>
        <graphic xlink:href="medinform_v9i2e25183_fig2.png" alt-version="no" mimetype="image" position="float" xlink:type="simple"/>
      </fig>
      <sec>
        <title>Predeployment Conditions</title>
        <p>In every clinic in the hospital, an early meeting is held in which all physicians meet to discuss patients collaboratively and to derive diagnoses and therapies (eg, E1, E2, and E5). Physicians from other disciplines frequently participate by offering their medical expertise. Afterward, physicians conduct ward rounds, perform surgeries, or treat patients. In many disciplines, additional meetings are held in the afternoon to discuss treatment procedures for specific patients:</p>
        <disp-quote>
          <p>It depends a bit on the department, but it is generally discussed who is assigned where, the night shift is discussed, X-rays are viewed together with a radiologist, at noon there is another meeting in which current cases are discussed with the senior and chief physician.</p>
          <attrib>E5</attrib>
        </disp-quote>
        <p>Collaboration between physicians in hospitals is characterized by face-to-face or telephone communication (eg, E4, E10, E12, E14). In many cases, personal communication is conducted on the same hierarchical level and within departmental boundaries. For example, information exchange among resident physicians takes place in person, while senior physicians or head physicians are usually approached via telephone:</p>
        <disp-quote>
          <p>Much usually happens verbally, with colleagues from the same level.</p>
          <attrib>E3</attrib>
        </disp-quote>
        <disp-quote>
          <p>Most personal communication with other resident physicians is according to our schedule. If I need to talk to a senior physician, I usually call him [or her].</p>
          <attrib>E2</attrib>
        </disp-quote>
        <p>However, not every physician has their own phone; some have pagers (eg, E1, E6). If it is necessary to contact a physician, the number of their pager is called from any telephone in the clinic. The pager will then display the number of the caller with a request for a callback. The physician must find a telephone to respond to the call. Up to this point, the identity of the caller and the reason for the call remain uncertain. In our study, the physicians explained that no official IT system facilitates collaboration (eg, E1, E5, E12). It was also described that existing IT systems lack ease of use and are rather difficult to handle. Furthermore, the velocity of the current infrastructure needs improvement, and retrieving information is not straightforward because medical data are stored across systems (eg, E3, E6, E12):</p>
        <disp-quote>
          <p>In the rarest cases communication is done by email, but only when I am sitting in my office. There is no use of any IT system; we are rather old-school.</p>
          <attrib>E6</attrib>
        </disp-quote>
        <disp-quote>
          <p>Systems are frequently just slow. Handling is not intuitive and programs crash.</p>
          <attrib>E3</attrib>
        </disp-quote>
        <p>The physicians reported that communication and collaboration in the hospital are sufficient but are dependent on collaborators adhering to certain organizational structures and communication channels (eg, E1, E7). Problems occasionally arise, such as misunderstandings in shift plans; colleagues can be difficult or impossible to reach, such as when a physician is in the operating theatre; or a faulty transfer from aftercare to day care can be made when information is captured in handwriting (eg, E2, E8, E9):</p>
        <disp-quote>
          <p>There are problems when changing shifts if a list has only been filled out by hand and you do not see each other.</p>
          <attrib>E8</attrib>
        </disp-quote>
        <p>However, the physicians explained that no serious issues arise during habitual collaboration (eg, E9, E13, E14) but likewise admitted that the current mode of communication is not being questioned and certainly could benefit from adjustments (eg, E1, E11, E12).</p>
      </sec>
      <sec>
        <title>Collaboration During the COVID-19 Pandemic</title>
        <p>Prior to the pandemic, Microsoft Teams was not used in the clinic, nor did any other standardized system exist for collaboration between clinicians in the hospital.</p>
        <p>The technological support for the collaboration was equally accepted, but some behaviors changed. Due to the reduction of personal contact between clinicians, the communication was more professional and less social (eg, E2, E6, E10, E14, E16). Communication over the telephone decreased significantly, and many issues were resolved directly via chat. In addition, response times were shorter, and information was shared digitally (eg, E3, E8, E10, E14):</p>
        <disp-quote>
          <p>It is already a somewhat different culture which is much more impersonal. There is less personal interaction.</p>
          <attrib>E5</attrib>
        </disp-quote>
        <p>The experts saw various advantages in technical assistance for collaboration. Foremost was compliance with the current rules and hygiene regulations (eg, E1-E6). Collaboration between physicians became easier. Data could be shared directly with everyone, and information was immediately captured digitally. Physicians could access data from anywhere, and even a physician who had not attended a meeting could obtain information via digital protocols. Colleagues could be reached much more quickly, and interdepartmental communication was simplified (eg, E5, E9, E12):</p>
        <disp-quote>
          <p>My colleagues are easier to reach, there is a closer connection between us. Medical information is available for everyone and decisions can be made faster and better.</p>
          <attrib>E8</attrib>
        </disp-quote>
        <p>In addition, the IT system simplified group meetings. The experts often complained that in large meeting rooms, the presentation screen was simply too far away (eg, E1, E2, E16). Relevant information was more visible; for example, patient x-rays could be interpreted more easily. Resident physicians reported a learning effect from the joint discussions of pictures (eg, E9, E13, E16):</p>
        <disp-quote>
          <p>When you look at the pictures, you get more opinions, they can be used as a basis for a decision, someone can also intervene, if you can see the pictures well, there is also a learning effect.</p>
          <attrib>E4</attrib>
        </disp-quote>
        <p>Meeting via Microsoft Teams was also perceived by the physicians as less stressful and more efficient (eg, E5, E7). Information could be looked up quickly during an appointment. Subsequent discussions could be kept within limits, and there was no longer a need to wait for participants on their way to a meeting room (eg, E8, E13). In addition, there was no need to use unknown hardware from an unfamiliar room for a presentation. Furthermore, experts reported that one could better prepare for transferring patient information:</p>
        <disp-quote>
          <p>As a physician, you can prepare yourself better, the information is already there. Everyone can prepare themselves and you don't have to do it together.</p>
          <attrib>E4</attrib>
        </disp-quote>
        <p>In addition, the physicians recognized indirect advantages for patients. The more effective and efficient appointments saved time, which could be used for more relevant tasks such as diagnosis or planning treatment. Through the joint discussion of patient reports, several professional opinions could be obtained, possibly leading to better decision-making (eg, E6, E12, E14). Finally, in the time of the pandemic, the potential risk of infection was minimized:</p>
        <disp-quote>
          <p>I believe we physicians are the greatest threat to everyone.</p>
          <attrib>E9</attrib>
        </disp-quote>
        <p>This new type of collaboration requires cognitive effort and a high level of self-discipline. Physicians have a highly interactive job. During a pandemic, they are not always allowed to meet a colleague and must encourage themselves to participate in digital communication. There is a feeling of a need to be constantly available, which creates stress and the perception of being controlled (eg, E4, E8, E9). A physician is always expected to be up to date, even when working from home or when on vacation:</p>
        <disp-quote>
          <p>But it is expected that you always look in and up to date, even if you are at home you still look in there, you are afraid to miss something out.</p>
          <attrib>E7</attrib>
        </disp-quote>
        <p>Finally, challenges of the collaborative adjustment were described. In addition to the partially slow internet connection, the new hardware had to be purchased quickly. Very few computers were equipped with proper cameras, microphones, or loudspeakers; therefore, collaboration with colleagues was more difficult (eg, E1, E2, E12):</p>
        <disp-quote>
          <p>Everybody had to install the software by himself and hardware was only available little by little. I couldn't log in from the office. The internet connection was bad so that people couldn't understand each other.</p>
          <attrib>E2</attrib>
        </disp-quote>
        <p>The system had many diverse users, such as resident and senior physicians. The system was used with varying degrees of intensity and not to its full extent. The full range of functions of the software was not manageable from the beginning, and the users were required to learn the functions themselves (eg, E2, E7, E12):</p>
        <disp-quote>
          <p>Everyone used it the way they thought was right. We just got it.</p>
          <attrib>E11</attrib>
        </disp-quote>
      </sec>
      <sec>
        <title>A Vision of the Future</title>
        <p>In the last part of the interviews, we asked the physicians how a future collaboration supported by technology would look. Some stated that Microsoft Teams should continue to be used, as it is broadly accepted and adopted (eg, E1, E2, E7). In addition, the change from classical messaging apps such as WhatsApp toward Microsoft Teams for professional purposes was already visible (eg, E7, E8):</p>
        <disp-quote>
          <p>Organizational things are shared different. It just works better.</p>
          <attrib>E7</attrib>
        </disp-quote>
        <p>However, the different types and levels of use must be considered. On the one hand, the technological support for collaboration should be further integrated. For example, physicians tend to continue virtual meetings in the future, as those are particularly helpful when individuals from different clinical disciplines need to participate and the physical attendance of participants is not required (eg, E3, E4, E11). In addition, information exchange among physicians is likely to change, as medical data are easier to retrieve (eg, E6, E13):</p>
        <disp-quote>
          <p>I would like to keep the tumor board meetings going like this. Everyone sits at their own workplace; x-ray images are easier to see and disease patterns better to recognize; ad-hoc information for a specific case can be obtained quickly.</p>
          <attrib>E5</attrib>
        </disp-quote>
        <disp-quote>
          <p>I think we should continue to use this especially for appointments that are attended by many people from different disciplines or in the future for such things as e-learning on surgery techniques.</p>
          <attrib>E3</attrib>
        </disp-quote>
        <disp-quote>
          <p>There are some useful areas where we can use [Microsoft] Teams. A lot of our digital communication is conducted via email. I think this might be limitable or even replaceable for internal information exchange.</p>
          <attrib>E6</attrib>
        </disp-quote>
        <p>On the other hand, personal contact is still fruitful and frequently the more favored means of collaboration. Especially for younger physicians, who are at the beginning of their medical training and rather inexperienced, personal contact is indispensable for conveying medical knowledge and demonstrating practical techniques on patients (eg, E1, E15, E16). Furthermore, mere virtual communication may result in negative consequences for teamwork and team spirit in the hospital (eg, E2, E5, E13):</p>
        <disp-quote>
          <p>When someone explains something to me, it’s easier to understand when we meet in person. I can't imagine how virtual meetings look like when treating or operating patients where it is about the practical execution.</p>
          <attrib>E15</attrib>
        </disp-quote>
        <disp-quote>
          <p>We spend so much time together, I sometimes want personal interaction with my colleagues. Unfortunately, this is currently somewhat lost.</p>
          <attrib>E13</attrib>
        </disp-quote>
        <disp-quote>
          <p>I think [virtual collaboration] is especially beneficial when you already know each other and each other’s work.</p>
          <attrib>E5</attrib>
        </disp-quote>
        <p>Therefore, not every type of collaboration should be supported or replaced by technology. However, the physicians explained that the current pandemic is forcing hospitals to undertake collaborative alignments (eg, E4-E8) as necessary endeavors to limit personal contact to a minimum, some of which should have been undertaken even sooner (eg, E4, E9):</p>
        <disp-quote>
          <p>We should continue this kind of virtual collaboration. I think we need to cope with the restrictions [due to the pandemic] for some time.</p>
          <attrib>E10</attrib>
        </disp-quote>
        <disp-quote>
          <p>We need the implementation as quickly as possible during a pandemic.</p>
          <attrib>E7</attrib>
        </disp-quote>
        <p>Finally, technology may improve not only collaborations among physicians (and other clinicians) but those with external partners. For example, some physicians reported that scientific collaborations have been initiated for research purposes (eg, E1, E2) with participants across departmental boundaries, that is, from internal clinics, external laboratories, and independent institutions.</p>
      </sec>
    </sec>
    <sec sec-type="discussion">
      <title>Discussion</title>
      <p>In this section, we present the most relevant insights gained from our case study. We explain general key lessons learned and offer recommendations on how digital transformation can improve collaboration. Our goal is to guide hospitals and their decision makers who want to embrace digital transformation for collaborative purposes.</p>
      <sec>
        <title>Lesson 1: Organizational Change Requires Alignment of the Mindset</title>
        <p>Digital transformation can change the way clinicians collaborate in hospitals. Achieving organizational change is not easy in surroundings that are characterized by hierarchical and authoritarian individuals [<xref ref-type="bibr" rid="ref36">36</xref>]. IT-enabled transformation does not always proceed as desired [<xref ref-type="bibr" rid="ref40">40</xref>], as working practices in hospitals have not greatly changed in the last few decades. Although the technological possibilities have matured and investments continue to rise [<xref ref-type="bibr" rid="ref64">64</xref>], collaboration is still conducted with common, proven instruments [<xref ref-type="bibr" rid="ref65">65</xref>].</p>
        <p>In our study, the physicians’ experience was that the assistance of an IT system simplified tasks in many areas of their daily working life. Simplification enhanced adaptations in the types of collaboration, moving from personal contact to a virtual environment. Aligning one’s mindset required a high degree of self-control to avoid falling back into habitual patterns. One expert described this as “a different kind of communication that requires effort and self-discipline in a profession that is strongly characterized by personal interaction” [E5]. However, physicians observed that this alignment is necessary because “otherwise everyone wants to do it like we did before” [E2].</p>
        <p>Recommendation: Hospitals should develop an overarching adoption strategy to meet the varying expectations of involved stakeholders. The introduction of technology today differs from that of 20 years ago. IT is simply a means to an end, and it should not be the center of attention. Instead, it provides a new way of working and of transforming certain processes. The entrenched mindset can only be changed piece by piece, accompanied by a variety of formats. This deliberate process might include different training sessions or workshops, such as how clinicians can collaborate to jointly develop an IT system to support, improve, or even completely replace certain processes.</p>
      </sec>
      <sec>
        <title>Lesson 2: Develop and Adhere to Behavioral Rules for Collaboration</title>
        <p>Enabling new forms of collaborative work drives operational performance, not only within the clinic but across departmental boundaries [<xref ref-type="bibr" rid="ref30">30</xref>,<xref ref-type="bibr" rid="ref31">31</xref>]. The introduction of IT systems in hospitals is transformative and may be disruptive [<xref ref-type="bibr" rid="ref66">66</xref>]. Furthermore, technological capabilities are broadly available to improve information exchange and collaboration [<xref ref-type="bibr" rid="ref45">45</xref>-<xref ref-type="bibr" rid="ref47">47</xref>]. The existence of technology does not necessarily describe how to handle that technology. Systems may be used in various ways; however, there is no “right” or “wrong” when it comes to the individual handling of a system.</p>
        <p>In our work, physicians described a system that is used for different purposes with various functions. Some clinicians conducted video calls, while others used the chat function or shared files. Many questions remained unanswered: Which functions should be used at all? How quickly should one react to chat messages? Is a reaction also expected outside regular working hours? Which files are shared, and in what type of structure are they stored? Questions should be clarified in advance to ensure a structured collaboration. One expert explained that “there were communication problems, cameras were bought without anyone knowing. We need rules on how to act and how to behave” [E2].</p>
        <p>Recommendation: Before or during the introduction of new technology, each clinic should define rules for its behavior and IT-enabled collaboration with stakeholders. Changes can never be initiated and sustained alone. The goal of improved collaboration and thus enhanced patient care can only be achieved if everyone participates and follows certain rules. The change should be embraced collaboratively.</p>
      </sec>
      <sec>
        <title>Lesson 3: Antiquated Technical Infrastructure Hinders a Shift</title>
        <p>Achieving cross-functional collaboration among hospital physicians presupposes the integration of suitable technologies to improve the overall treatment of patients [<xref ref-type="bibr" rid="ref27">27</xref>,<xref ref-type="bibr" rid="ref28">28</xref>]. To enhance the overall diagnostic and treatment process further requires IT systems with stored information to be accurate, relevant and integrated as well as quickly accessible when needed [<xref ref-type="bibr" rid="ref35">35</xref>,<xref ref-type="bibr" rid="ref36">36</xref>]. However, hospitals still struggle to adopt new technologies in their complex clinical environments and to integrate them into their underlying infrastructure [<xref ref-type="bibr" rid="ref52">52</xref>].</p>
        <p>Our results revealed that physicians appreciated the IT-enabled support and wanted to continue to use it; however, they felt restricted due to technical problems. The participants reported that the internet connection in the hospital regularly failed or was only adequate for transmitting sound without a video signal. In addition, the computers were all stationary and frequently outdated. The lack of devices, in turn, led to many physicians using private devices, on which data protection and security were problematic. Physicians simply observed that “the infrastructure must be available” [E1] and “the technology must be upgraded and ideally interlinked in all parts of the health care system” [E4].</p>
        <p>Recommendation: Hospitals must provide technical fundamentals to promote IT-enabled collaboration between physicians. This training applies not only to the infrastructure itself, such as network availability, but to the technical equipment. Every physician could be equipped with appropriate devices such as notebooks, tablets, or smartphones. A positive outcome of this would be that the equipment managed by the clinic’s IT department would comply with data protection regulations.</p>
      </sec>
      <sec>
        <title>Conclusions</title>
        <p>Digital transformation, with all of its disruptive approaches, improves collaboration between clinicians, not only during crises such as the COVID-19 pandemic. Hospitals are slowly turning into smart hospitals that incorporate innovative technologies with optimized and automated processes to provide better patient care [<xref ref-type="bibr" rid="ref42">42</xref>-<xref ref-type="bibr" rid="ref44">44</xref>]. Technical advancements had been available before [<xref ref-type="bibr" rid="ref45">45</xref>-<xref ref-type="bibr" rid="ref47">47</xref>]; however, a crisis forced the introduction of IT-enabled assistance [<xref ref-type="bibr" rid="ref55">55</xref>]. The reduction of personal contact among physicians to contain the virus and lower the infection rate was the ultimate objective.</p>
        <p>In our study, physicians positively reviewed the introduction of the IT system to enhance collaboration in their hospital. However, it is necessary to ensure that the technical basis for the use of the system is available. Furthermore, it takes time for an organizational change to be embraced. Finally, rules for virtual collaboration should be defined and should be followed by every stakeholder.</p>
        <p>The rapid and unavoidable introduction of IT-enabled collaboration revealed profound grievances concerning the technological requirements of hospitals and the digital expertise of clinicians. Digital dissemination of medical information along the patient treatment path is not entirely complete. Medical data are exchanged verbally or in handwriting and are often not available throughout the hospital [<xref ref-type="bibr" rid="ref15">15</xref>,<xref ref-type="bibr" rid="ref22">22</xref>]. Technology has found its way into our everyday lives, but physicians are still not fully aware of the possibilities that digital transformation reveals [<xref ref-type="bibr" rid="ref65">65</xref>]. There is a lack of practice and actual use within hospitals, as IT-enabled collaboration is not necessarily needed, and the health care sector traditionally lags in adopting new technologies [<xref ref-type="bibr" rid="ref30">30</xref>,<xref ref-type="bibr" rid="ref67">67</xref>].</p>
        <p>To avoid being caught unprepared by future crises, digital transformation must be further driven to ensure effective and efficient collaboration even without personal contact. Such virtual collaboration requires the diagnostic process and subsequent treatment to be opened to disruptive strategies. Openness will not only contribute to faster change but will embrace patient-oriented behavior. Moreover, a rapid rollout contributes to quicker adoption. The adoption of pragmatic and innovative solutions will increase their acceptance for future use.</p>
      </sec>
    </sec>
  </body>
  <back>
    <app-group/>
    <glossary>
      <title>Abbreviations</title>
      <def-list>
        <def-item>
          <term id="abb1">AI</term>
          <def>
            <p>artificial intelligence</p>
          </def>
        </def-item>
        <def-item>
          <term id="abb2">CSCW</term>
          <def>
            <p>computer-supported cooperative work</p>
          </def>
        </def-item>
        <def-item>
          <term id="abb3">EHR</term>
          <def>
            <p>electronic health record</p>
          </def>
        </def-item>
        <def-item>
          <term id="abb4">HIT</term>
          <def>
            <p>health information technology</p>
          </def>
        </def-item>
        <def-item>
          <term id="abb5">IoT</term>
          <def>
            <p>Internet of Things</p>
          </def>
        </def-item>
        <def-item>
          <term id="abb6">IT</term>
          <def>
            <p>information technology</p>
          </def>
        </def-item>
      </def-list>
    </glossary>
    <fn-group>
      <fn fn-type="conflict">
        <p>None declared.</p>
      </fn>
    </fn-group>
    <ref-list>
      <ref id="ref1">
        <label>1</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Lipsitch</surname>
              <given-names>M</given-names>
            </name>
            <name name-style="western">
              <surname>Swerdlow</surname>
              <given-names>DL</given-names>
            </name>
            <name name-style="western">
              <surname>Finelli</surname>
              <given-names>L</given-names>
            </name>
          </person-group>
          <article-title>Defining the Epidemiology of Covid-19 — Studies Needed</article-title>
          <source>N Engl J Med</source>
          <year>2020</year>
          <month>03</month>
          <day>26</day>
          <volume>382</volume>
          <issue>13</issue>
          <fpage>1194</fpage>
          <lpage>1196</lpage>
          <pub-id pub-id-type="doi">10.1056/nejmp2002125</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref2">
        <label>2</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Shen</surname>
              <given-names>Y</given-names>
            </name>
            <name name-style="western">
              <surname>Cui</surname>
              <given-names>Y</given-names>
            </name>
            <name name-style="western">
              <surname>Li</surname>
              <given-names>N</given-names>
            </name>
            <name name-style="western">
              <surname>Tian</surname>
              <given-names>C</given-names>
            </name>
            <name name-style="western">
              <surname>Chen</surname>
              <given-names>M</given-names>
            </name>
            <name name-style="western">
              <surname>Zhang</surname>
              <given-names>Y</given-names>
            </name>
            <name name-style="western">
              <surname>Huang</surname>
              <given-names>Y</given-names>
            </name>
            <name name-style="western">
              <surname>Chen</surname>
              <given-names>H</given-names>
            </name>
            <name name-style="western">
              <surname>Kong</surname>
              <given-names>Q</given-names>
            </name>
            <name name-style="western">
              <surname>Zhang</surname>
              <given-names>Q</given-names>
            </name>
            <name name-style="western">
              <surname>Teng</surname>
              <given-names>G</given-names>
            </name>
          </person-group>
          <article-title>Emergency Responses to Covid-19 Outbreak: Experiences and Lessons from a General Hospital in Nanjing, China</article-title>
          <source>Cardiovasc Intervent Radiol</source>
          <year>2020</year>
          <month>06</month>
          <volume>43</volume>
          <issue>6</issue>
          <fpage>810</fpage>
          <lpage>819</lpage>
          <comment>
            <ext-link ext-link-type="uri" xlink:type="simple" xlink:href="http://europepmc.org/abstract/MED/32342164"/>
          </comment>
          <pub-id pub-id-type="doi">10.1007/s00270-020-02474-w</pub-id>
          <pub-id pub-id-type="medline">32342164</pub-id>
          <pub-id pub-id-type="pii">2474</pub-id>
          <pub-id pub-id-type="pmcid">PMC7184943</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref3">
        <label>3</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Wong</surname>
              <given-names>J</given-names>
            </name>
            <name name-style="western">
              <surname>Goh</surname>
              <given-names>QY</given-names>
            </name>
            <name name-style="western">
              <surname>Tan</surname>
              <given-names>Z</given-names>
            </name>
            <name name-style="western">
              <surname>Lie</surname>
              <given-names>SA</given-names>
            </name>
            <name name-style="western">
              <surname>Tay</surname>
              <given-names>YC</given-names>
            </name>
            <name name-style="western">
              <surname>Ng</surname>
              <given-names>SY</given-names>
            </name>
            <name name-style="western">
              <surname>Soh</surname>
              <given-names>CR</given-names>
            </name>
          </person-group>
          <article-title>Preparing for a COVID-19 pandemic: a review of operating room outbreak response measures in a large tertiary hospital in Singapore</article-title>
          <source>Can J Anaesth</source>
          <year>2020</year>
          <month>06</month>
          <day>11</day>
          <volume>67</volume>
          <issue>6</issue>
          <fpage>732</fpage>
          <lpage>745</lpage>
          <comment>
            <ext-link ext-link-type="uri" xlink:type="simple" xlink:href="http://europepmc.org/abstract/MED/32162212"/>
          </comment>
          <pub-id pub-id-type="doi">10.1007/s12630-020-01620-9</pub-id>
          <pub-id pub-id-type="medline">32162212</pub-id>
          <pub-id pub-id-type="pii">10.1007/s12630-020-01620-9</pub-id>
          <pub-id pub-id-type="pmcid">PMC7090449</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref4">
        <label>4</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Gilbert</surname>
              <given-names>J</given-names>
            </name>
            <name name-style="western">
              <surname>Yan</surname>
              <given-names>J</given-names>
            </name>
            <name name-style="western">
              <surname>Hoffman</surname>
              <given-names>S</given-names>
            </name>
          </person-group>
          <article-title>A WHO report: framework for action on interprofessional education and collaborative practice</article-title>
          <source>J Allied Health</source>
          <year>2010</year>
          <volume>39 Suppl 1</volume>
          <fpage>196</fpage>
          <lpage>7</lpage>
          <pub-id pub-id-type="medline">21174039</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref5">
        <label>5</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>McInnes</surname>
              <given-names>S</given-names>
            </name>
            <name name-style="western">
              <surname>Peters</surname>
              <given-names>K</given-names>
            </name>
            <name name-style="western">
              <surname>Bonney</surname>
              <given-names>A</given-names>
            </name>
            <name name-style="western">
              <surname>Halcomb</surname>
              <given-names>E</given-names>
            </name>
          </person-group>
          <article-title>An integrative review of facilitators and barriers influencing collaboration and teamwork between general practitioners and nurses working in general practice</article-title>
          <source>J Adv Nurs</source>
          <year>2015</year>
          <month>09</month>
          <volume>71</volume>
          <issue>9</issue>
          <fpage>1973</fpage>
          <lpage>85</lpage>
          <pub-id pub-id-type="doi">10.1111/jan.12647</pub-id>
          <pub-id pub-id-type="medline">25731727</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref6">
        <label>6</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Wagner</surname>
              <given-names>EH</given-names>
            </name>
            <name name-style="western">
              <surname>Austin</surname>
              <given-names>BT</given-names>
            </name>
            <name name-style="western">
              <surname>Davis</surname>
              <given-names>C</given-names>
            </name>
            <name name-style="western">
              <surname>Hindmarsh</surname>
              <given-names>M</given-names>
            </name>
            <name name-style="western">
              <surname>Schaefer</surname>
              <given-names>J</given-names>
            </name>
            <name name-style="western">
              <surname>Bonomi</surname>
              <given-names>A</given-names>
            </name>
          </person-group>
          <article-title>Improving chronic illness care: translating evidence into action</article-title>
          <source>Health Aff (Millwood)</source>
          <year>2001</year>
          <volume>20</volume>
          <issue>6</issue>
          <fpage>64</fpage>
          <lpage>78</lpage>
          <pub-id pub-id-type="doi">10.1377/hlthaff.20.6.64</pub-id>
          <pub-id pub-id-type="medline">11816692</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref7">
        <label>7</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Rosen</surname>
              <given-names>MA</given-names>
            </name>
            <name name-style="western">
              <surname>DiazGranados</surname>
              <given-names>D</given-names>
            </name>
            <name name-style="western">
              <surname>Dietz</surname>
              <given-names>AS</given-names>
            </name>
            <name name-style="western">
              <surname>Benishek</surname>
              <given-names>LE</given-names>
            </name>
            <name name-style="western">
              <surname>Thompson</surname>
              <given-names>D</given-names>
            </name>
            <name name-style="western">
              <surname>Pronovost</surname>
              <given-names>PJ</given-names>
            </name>
            <name name-style="western">
              <surname>Weaver</surname>
              <given-names>SJ</given-names>
            </name>
          </person-group>
          <article-title>Teamwork in healthcare: Key discoveries enabling safer, high-quality care</article-title>
          <source>Am Psychol</source>
          <year>2018</year>
          <month>05</month>
          <volume>73</volume>
          <issue>4</issue>
          <fpage>433</fpage>
          <lpage>450</lpage>
          <comment>
            <ext-link ext-link-type="uri" xlink:type="simple" xlink:href="http://europepmc.org/abstract/MED/29792459"/>
          </comment>
          <pub-id pub-id-type="doi">10.1037/amp0000298</pub-id>
          <pub-id pub-id-type="medline">29792459</pub-id>
          <pub-id pub-id-type="pii">2018-23205-011</pub-id>
          <pub-id pub-id-type="pmcid">PMC6361117</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref8">
        <label>8</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>D'Amour</surname>
              <given-names>D</given-names>
            </name>
            <name name-style="western">
              <surname>Goulet</surname>
              <given-names>L</given-names>
            </name>
            <name name-style="western">
              <surname>Labadie</surname>
              <given-names>J</given-names>
            </name>
            <name name-style="western">
              <surname>Martín-Rodriguez</surname>
              <given-names>LS</given-names>
            </name>
            <name name-style="western">
              <surname>Pineault</surname>
              <given-names>R</given-names>
            </name>
          </person-group>
          <article-title>A model and typology of collaboration between professionals in healthcare organizations</article-title>
          <source>BMC Health Serv Res</source>
          <year>2008</year>
          <month>09</month>
          <day>21</day>
          <volume>8</volume>
          <fpage>188</fpage>
          <comment>
            <ext-link ext-link-type="uri" xlink:type="simple" xlink:href="https://bmchealthservres.biomedcentral.com/articles/10.1186/1472-6963-8-188"/>
          </comment>
          <pub-id pub-id-type="doi">10.1186/1472-6963-8-188</pub-id>
          <pub-id pub-id-type="medline">18803881</pub-id>
          <pub-id pub-id-type="pii">1472-6963-8-188</pub-id>
          <pub-id pub-id-type="pmcid">PMC2563002</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref9">
        <label>9</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Lenz</surname>
              <given-names>R</given-names>
            </name>
            <name name-style="western">
              <surname>Reichert</surname>
              <given-names>M</given-names>
            </name>
          </person-group>
          <article-title>IT support for healthcare processes – premises, challenges, perspectives</article-title>
          <source>Data Knowl Eng</source>
          <year>2007</year>
          <month>4</month>
          <volume>61</volume>
          <issue>1</issue>
          <fpage>39</fpage>
          <lpage>58</lpage>
          <comment>
            <ext-link ext-link-type="uri" xlink:type="simple" xlink:href="https://doi.org/10.1111/j.1553-2712.2012.01435.x"/>
          </comment>
          <pub-id pub-id-type="doi">10.1016/j.datak.2006.04.007</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref10">
        <label>10</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>McCaffrey</surname>
              <given-names>RG</given-names>
            </name>
            <name name-style="western">
              <surname>Hayes</surname>
              <given-names>R</given-names>
            </name>
            <name name-style="western">
              <surname>Stuart</surname>
              <given-names>W</given-names>
            </name>
            <name name-style="western">
              <surname>Cassell</surname>
              <given-names>A</given-names>
            </name>
            <name name-style="western">
              <surname>Farrell</surname>
              <given-names>C</given-names>
            </name>
            <name name-style="western">
              <surname>Miller-Reyes</surname>
              <given-names>C</given-names>
            </name>
            <name name-style="western">
              <surname>Donaldson</surname>
              <given-names>A</given-names>
            </name>
          </person-group>
          <article-title>A program to improve communication and collaboration between nurses and medical residents</article-title>
          <source>J Contin Educ Nurs</source>
          <year>2010</year>
          <month>04</month>
          <day>01</day>
          <volume>41</volume>
          <issue>4</issue>
          <fpage>172</fpage>
          <lpage>8</lpage>
          <pub-id pub-id-type="doi">10.3928/00220124-20100326-04</pub-id>
          <pub-id pub-id-type="medline">20411889</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref11">
        <label>11</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Zwarenstein</surname>
              <given-names>M</given-names>
            </name>
            <name name-style="western">
              <surname>Goldman</surname>
              <given-names>J</given-names>
            </name>
            <name name-style="western">
              <surname>Reeves</surname>
              <given-names>S</given-names>
            </name>
          </person-group>
          <article-title>Interprofessional collaboration: effects of practice‐based interventions on professional practice and healthcare outcomes</article-title>
          <source>Cochrane Database Syst Rev</source>
          <year>2009</year>
          <issue>3</issue>
          <pub-id pub-id-type="doi">10.1002/14651858.cd000072.pub2</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref12">
        <label>12</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Schot</surname>
              <given-names>E</given-names>
            </name>
            <name name-style="western">
              <surname>Tummers</surname>
              <given-names>L</given-names>
            </name>
            <name name-style="western">
              <surname>Noordegraaf</surname>
              <given-names>M</given-names>
            </name>
          </person-group>
          <article-title>Working on working together. A systematic review on how healthcare professionals contribute to interprofessional collaboration</article-title>
          <source>J Interprof Care</source>
          <year>2020</year>
          <volume>34</volume>
          <issue>3</issue>
          <fpage>332</fpage>
          <lpage>342</lpage>
          <pub-id pub-id-type="doi">10.1080/13561820.2019.1636007</pub-id>
          <pub-id pub-id-type="medline">31329469</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref13">
        <label>13</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Morgan</surname>
              <given-names>S</given-names>
            </name>
            <name name-style="western">
              <surname>Pullon</surname>
              <given-names>S</given-names>
            </name>
            <name name-style="western">
              <surname>McKinlay</surname>
              <given-names>E</given-names>
            </name>
          </person-group>
          <article-title>Observation of interprofessional collaborative practice in primary care teams: An integrative literature review</article-title>
          <source>Int J Nurs Stud</source>
          <year>2015</year>
          <month>07</month>
          <volume>52</volume>
          <issue>7</issue>
          <fpage>1217</fpage>
          <lpage>30</lpage>
          <pub-id pub-id-type="doi">10.1016/j.ijnurstu.2015.03.008</pub-id>
          <pub-id pub-id-type="medline">25862411</pub-id>
          <pub-id pub-id-type="pii">S0020-7489(15)00070-X</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref14">
        <label>14</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Leggat</surname>
              <given-names>SG</given-names>
            </name>
          </person-group>
          <article-title>Effective healthcare teams require effective team members: defining teamwork competencies</article-title>
          <source>BMC Health Serv Res</source>
          <year>2007</year>
          <month>02</month>
          <day>07</day>
          <volume>7</volume>
          <fpage>17</fpage>
          <comment>
            <ext-link ext-link-type="uri" xlink:type="simple" xlink:href="https://bmchealthservres.biomedcentral.com/articles/10.1186/1472-6963-7-17"/>
          </comment>
          <pub-id pub-id-type="doi">10.1186/1472-6963-7-17</pub-id>
          <pub-id pub-id-type="medline">17284324</pub-id>
          <pub-id pub-id-type="pii">1472-6963-7-17</pub-id>
          <pub-id pub-id-type="pmcid">PMC1800844</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref15">
        <label>15</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Mirbabaie</surname>
              <given-names>M</given-names>
            </name>
            <name name-style="western">
              <surname>Stieglitz</surname>
              <given-names>S</given-names>
            </name>
            <name name-style="western">
              <surname>Frick</surname>
              <given-names>N</given-names>
            </name>
          </person-group>
          <article-title>Hybrid Intelligence in Hospitals - Towards a Research Agenda for Collaboration</article-title>
          <source>Electron Mark 2021;forthcoming</source>
          <year>2021</year>
        </nlm-citation>
      </ref>
      <ref id="ref16">
        <label>16</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Kripalani</surname>
              <given-names>S</given-names>
            </name>
            <name name-style="western">
              <surname>LeFevre</surname>
              <given-names>F</given-names>
            </name>
            <name name-style="western">
              <surname>Phillips</surname>
              <given-names>CO</given-names>
            </name>
            <name name-style="western">
              <surname>Williams</surname>
              <given-names>MV</given-names>
            </name>
            <name name-style="western">
              <surname>Basaviah</surname>
              <given-names>P</given-names>
            </name>
            <name name-style="western">
              <surname>Baker</surname>
              <given-names>DW</given-names>
            </name>
          </person-group>
          <article-title>Deficits in communication and information transfer between hospital-based and primary care physicians: implications for patient safety and continuity of care</article-title>
          <source>JAMA</source>
          <year>2007</year>
          <month>02</month>
          <day>28</day>
          <volume>297</volume>
          <issue>8</issue>
          <fpage>831</fpage>
          <lpage>41</lpage>
          <pub-id pub-id-type="doi">10.1001/jama.297.8.831</pub-id>
          <pub-id pub-id-type="medline">17327525</pub-id>
          <pub-id pub-id-type="pii">297/8/831</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref17">
        <label>17</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>McCracken</surname>
              <given-names>SS</given-names>
            </name>
            <name name-style="western">
              <surname>Edwards</surname>
              <given-names>JS</given-names>
            </name>
          </person-group>
          <article-title>Implementing a knowledge management system within an NHS hospital: a case study exploring the roll-out of an electronic patient record (EPR)</article-title>
          <source>Knowl Manag Res Pract</source>
          <year>2017</year>
          <month>12</month>
          <day>19</day>
          <volume>15</volume>
          <issue>1</issue>
          <fpage>1</fpage>
          <lpage>11</lpage>
          <pub-id pub-id-type="doi">10.1057/kmrp.2015.7</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref18">
        <label>18</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Driscoll</surname>
              <given-names>M</given-names>
            </name>
            <name name-style="western">
              <surname>Tobis</surname>
              <given-names>K</given-names>
            </name>
            <name name-style="western">
              <surname>Gurka</surname>
              <given-names>D</given-names>
            </name>
            <name name-style="western">
              <surname>Serafin</surname>
              <given-names>F</given-names>
            </name>
            <name name-style="western">
              <surname>Carlson</surname>
              <given-names>E</given-names>
            </name>
          </person-group>
          <article-title>Breaking down the silos to decrease internal diversions and patient flow delays</article-title>
          <source>Nurs Adm Q</source>
          <year>2015</year>
          <volume>39</volume>
          <issue>1</issue>
          <fpage>E1</fpage>
          <lpage>8</lpage>
          <pub-id pub-id-type="doi">10.1097/NAQ.0000000000000080</pub-id>
          <pub-id pub-id-type="medline">25474675</pub-id>
          <pub-id pub-id-type="pii">00006216-201501000-00020</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref19">
        <label>19</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Angst</surname>
              <given-names>CM</given-names>
            </name>
            <name name-style="western">
              <surname>Agarwal</surname>
              <given-names>R</given-names>
            </name>
            <name name-style="western">
              <surname>Sambamurthy</surname>
              <given-names>V</given-names>
            </name>
            <name name-style="western">
              <surname>Kelley</surname>
              <given-names>K</given-names>
            </name>
          </person-group>
          <article-title>Social Contagion and Information Technology Diffusion: The Adoption of Electronic Medical Records in U.S. Hospitals</article-title>
          <source>Manage Sci</source>
          <year>2010</year>
          <month>08</month>
          <volume>56</volume>
          <issue>8</issue>
          <fpage>1219</fpage>
          <lpage>1241</lpage>
          <pub-id pub-id-type="doi">10.1287/mnsc.1100.1183</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref20">
        <label>20</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Hanseth</surname>
              <given-names>O</given-names>
            </name>
            <name name-style="western">
              <surname>Bygstad</surname>
              <given-names>B</given-names>
            </name>
          </person-group>
          <article-title>Flexible generification: ICT standardization strategies and service innovation in health care</article-title>
          <source>Eur J Inf Syst</source>
          <year>2017</year>
          <month>12</month>
          <day>19</day>
          <volume>24</volume>
          <issue>6</issue>
          <fpage>645</fpage>
          <lpage>663</lpage>
          <pub-id pub-id-type="doi">10.1057/ejis.2015.1</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref21">
        <label>21</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Meier</surname>
              <given-names>J</given-names>
            </name>
            <name name-style="western">
              <surname>Boehm</surname>
              <given-names>A</given-names>
            </name>
            <name name-style="western">
              <surname>Kielhorn</surname>
              <given-names>A</given-names>
            </name>
            <name name-style="western">
              <surname>Dietz</surname>
              <given-names>A</given-names>
            </name>
            <name name-style="western">
              <surname>Bohn</surname>
              <given-names>S</given-names>
            </name>
            <name name-style="western">
              <surname>Neumuth</surname>
              <given-names>T</given-names>
            </name>
          </person-group>
          <article-title>Design and evaluation of a multimedia electronic patient record "oncoflow" with clinical workflow assistance for head and neck tumor therapy</article-title>
          <source>Int J Comput Assist Radiol Surg</source>
          <year>2014</year>
          <month>11</month>
          <day>27</day>
          <volume>9</volume>
          <issue>6</issue>
          <fpage>949</fpage>
          <lpage>65</lpage>
          <pub-id pub-id-type="doi">10.1007/s11548-014-0988-x</pub-id>
          <pub-id pub-id-type="medline">24573598</pub-id>
          <pub-id pub-id-type="pii">10.1007/s11548-014-0988-x</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref22">
        <label>22</label>
        <nlm-citation citation-type="web">
          <article-title>Driving the digital transformation of Germany's healthcare system for the good of patients</article-title>
          <source>Federal Ministry of Health, Germany</source>
          <access-date>2021-01-04</access-date>
          <comment>
            <ext-link ext-link-type="uri" xlink:type="simple" xlink:href="https://www.bundesgesundheitsministerium.de/digital-healthcare-act.html">https://www.bundesgesundheitsministerium.de/digital-healthcare-act.html</ext-link>
          </comment>
        </nlm-citation>
      </ref>
      <ref id="ref23">
        <label>23</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Baughman</surname>
              <given-names>AW</given-names>
            </name>
            <name name-style="western">
              <surname>Hirschberg</surname>
              <given-names>RE</given-names>
            </name>
            <name name-style="western">
              <surname>Lucas</surname>
              <given-names>LJ</given-names>
            </name>
            <name name-style="western">
              <surname>Suarez</surname>
              <given-names>ED</given-names>
            </name>
            <name name-style="western">
              <surname>Stockmann</surname>
              <given-names>D</given-names>
            </name>
            <name name-style="western">
              <surname>Hutton Johnson</surname>
              <given-names>S</given-names>
            </name>
            <name name-style="western">
              <surname>Hutter</surname>
              <given-names>MM</given-names>
            </name>
            <name name-style="western">
              <surname>Murphy</surname>
              <given-names>DJ</given-names>
            </name>
            <name name-style="western">
              <surname>Marsh</surname>
              <given-names>RH</given-names>
            </name>
            <name name-style="western">
              <surname>Thompson</surname>
              <given-names>RW</given-names>
            </name>
            <name name-style="western">
              <surname>Boland</surname>
              <given-names>GW</given-names>
            </name>
            <name name-style="western">
              <surname>Ives Erickson</surname>
              <given-names>J</given-names>
            </name>
            <name name-style="western">
              <surname>Palamara</surname>
              <given-names>K</given-names>
            </name>
          </person-group>
          <article-title>Pandemic Care Through Collaboration: Lessons From a COVID-19 Field Hospital</article-title>
          <source>J Am Med Dir Assoc</source>
          <year>2020</year>
          <month>11</month>
          <volume>21</volume>
          <issue>11</issue>
          <fpage>1563</fpage>
          <lpage>1567</lpage>
          <pub-id pub-id-type="doi">10.1016/j.jamda.2020.09.003</pub-id>
          <pub-id pub-id-type="medline">33138938</pub-id>
          <pub-id pub-id-type="pii">S1525-8610(20)30746-5</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref24">
        <label>24</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Sun</surname>
              <given-names>P</given-names>
            </name>
            <name name-style="western">
              <surname>Lu</surname>
              <given-names>X</given-names>
            </name>
            <name name-style="western">
              <surname>Xu</surname>
              <given-names>C</given-names>
            </name>
            <name name-style="western">
              <surname>Sun</surname>
              <given-names>W</given-names>
            </name>
            <name name-style="western">
              <surname>Pan</surname>
              <given-names>B</given-names>
            </name>
          </person-group>
          <article-title>Understanding of COVID-19 based on current evidence</article-title>
          <source>J Med Virol</source>
          <year>2020</year>
          <month>06</month>
          <volume>92</volume>
          <issue>6</issue>
          <fpage>548</fpage>
          <lpage>551</lpage>
          <comment>
            <ext-link ext-link-type="uri" xlink:type="simple" xlink:href="http://europepmc.org/abstract/MED/32096567"/>
          </comment>
          <pub-id pub-id-type="doi">10.1002/jmv.25722</pub-id>
          <pub-id pub-id-type="medline">32096567</pub-id>
          <pub-id pub-id-type="pmcid">PMC7228250</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref25">
        <label>25</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Burgansky</surname>
              <given-names>A</given-names>
            </name>
            <name name-style="western">
              <surname>Coletta-Lucas</surname>
              <given-names>J</given-names>
            </name>
            <name name-style="western">
              <surname>Garcia</surname>
              <given-names>MS</given-names>
            </name>
          </person-group>
          <article-title>COVID-19 in a community hospital</article-title>
          <source>Semin Perinatol</source>
          <year>2020</year>
          <month>10</month>
          <volume>44</volume>
          <issue>6</issue>
          <fpage>151292</fpage>
          <comment>
            <ext-link ext-link-type="uri" xlink:type="simple" xlink:href="http://europepmc.org/abstract/MED/32800406"/>
          </comment>
          <pub-id pub-id-type="doi">10.1016/j.semperi.2020.151292</pub-id>
          <pub-id pub-id-type="medline">32800406</pub-id>
          <pub-id pub-id-type="pii">S0146-0005(20)30075-6</pub-id>
          <pub-id pub-id-type="pmcid">PMC7376360</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref26">
        <label>26</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Archbald-Pannone</surname>
              <given-names>LR</given-names>
            </name>
            <name name-style="western">
              <surname>Harris</surname>
              <given-names>DA</given-names>
            </name>
            <name name-style="western">
              <surname>Albero</surname>
              <given-names>K</given-names>
            </name>
            <name name-style="western">
              <surname>Steele</surname>
              <given-names>RL</given-names>
            </name>
            <name name-style="western">
              <surname>Pannone</surname>
              <given-names>AF</given-names>
            </name>
            <name name-style="western">
              <surname>Mutter</surname>
              <given-names>JB</given-names>
            </name>
          </person-group>
          <article-title>COVID-19 Collaborative Model for an Academic Hospital and Long-Term Care Facilities</article-title>
          <source>J Am Med Dir Assoc</source>
          <year>2020</year>
          <month>07</month>
          <volume>21</volume>
          <issue>7</issue>
          <fpage>939</fpage>
          <lpage>942</lpage>
          <comment>
            <ext-link ext-link-type="uri" xlink:type="simple" xlink:href="http://europepmc.org/abstract/MED/32563752"/>
          </comment>
          <pub-id pub-id-type="doi">10.1016/j.jamda.2020.05.044</pub-id>
          <pub-id pub-id-type="medline">32563752</pub-id>
          <pub-id pub-id-type="pii">S1525-8610(20)30447-3</pub-id>
          <pub-id pub-id-type="pmcid">PMC7247468</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref27">
        <label>27</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Klinker</surname>
              <given-names>K</given-names>
            </name>
            <name name-style="western">
              <surname>Wiesche</surname>
              <given-names>M</given-names>
            </name>
            <name name-style="western">
              <surname>Krcmar</surname>
              <given-names>H</given-names>
            </name>
          </person-group>
          <article-title>Digital Transformation in Health Care: Augmented Reality for Hands-Free Service Innovation</article-title>
          <source>Inf Syst Front</source>
          <year>2019</year>
          <month>06</month>
          <day>25</day>
          <volume>22</volume>
          <issue>6</issue>
          <fpage>1419</fpage>
          <lpage>1431</lpage>
          <pub-id pub-id-type="doi">10.1007/s10796-019-09937-7</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref28">
        <label>28</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Gopal</surname>
              <given-names>G</given-names>
            </name>
            <name name-style="western">
              <surname>Suter-Crazzolara</surname>
              <given-names>C</given-names>
            </name>
            <name name-style="western">
              <surname>Toldo</surname>
              <given-names>L</given-names>
            </name>
            <name name-style="western">
              <surname>Eberhardt</surname>
              <given-names>W</given-names>
            </name>
          </person-group>
          <article-title>Digital transformation in healthcare - architectures of present and future information technologies</article-title>
          <source>Clin Chem Lab Med</source>
          <year>2019</year>
          <month>02</month>
          <day>25</day>
          <volume>57</volume>
          <issue>3</issue>
          <fpage>328</fpage>
          <lpage>335</lpage>
          <comment>
            <ext-link ext-link-type="uri" xlink:type="simple" xlink:href="https://www.degruyter.com/doi/10.1515/cclm-2018-0658"/>
          </comment>
          <pub-id pub-id-type="doi">10.1515/cclm-2018-0658</pub-id>
          <pub-id pub-id-type="medline">30530878</pub-id>
          <pub-id pub-id-type="pii">/j/cclm.ahead-of-print/cclm-2018-0658/cclm-2018-0658.xml</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref29">
        <label>29</label>
        <nlm-citation citation-type="confproc">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Klötzer</surname>
              <given-names>C</given-names>
            </name>
            <name name-style="western">
              <surname>Pflaum</surname>
              <given-names>A</given-names>
            </name>
          </person-group>
          <article-title>Toward the Development of a Maturity Model for Digitalization within the Manufacturing Industry's Supply Chain</article-title>
          <source>Proceedings of the 50th Hawaii International Conference on System Sciences</source>
          <year>2017</year>
          <conf-name>50th Hawaii International Conference on System Sciences</conf-name>
          <conf-date>January 4-7, 2017</conf-date>
          <conf-loc>Waikoloa Village, HI</conf-loc>
          <fpage>4210</fpage>
          <lpage>4219</lpage>
          <pub-id pub-id-type="doi">10.24251/hicss.2017.509</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref30">
        <label>30</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Vial</surname>
              <given-names>G</given-names>
            </name>
          </person-group>
          <article-title>Understanding digital transformation: A review and a research agenda</article-title>
          <source>J Strateg Inf Syst</source>
          <year>2019</year>
          <month>06</month>
          <volume>28</volume>
          <issue>2</issue>
          <fpage>118</fpage>
          <lpage>144</lpage>
          <pub-id pub-id-type="doi">10.1016/j.jsis.2019.01.003</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref31">
        <label>31</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Hess</surname>
              <given-names>T</given-names>
            </name>
            <name name-style="western">
              <surname>Benlian</surname>
              <given-names>A</given-names>
            </name>
            <name name-style="western">
              <surname>Matt</surname>
              <given-names>C</given-names>
            </name>
            <name name-style="western">
              <surname>Wiesböck</surname>
              <given-names>F</given-names>
            </name>
          </person-group>
          <article-title>Options for Formulating a Digital Transformation Strategy</article-title>
          <source>MIS Q Executive</source>
          <year>2016</year>
          <volume>15</volume>
          <issue>2</issue>
        </nlm-citation>
      </ref>
      <ref id="ref32">
        <label>32</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Frick</surname>
              <given-names>NRJ</given-names>
            </name>
            <name name-style="western">
              <surname>Mirbabaie</surname>
              <given-names>M</given-names>
            </name>
            <name name-style="western">
              <surname>Stieglitz</surname>
              <given-names>S</given-names>
            </name>
            <name name-style="western">
              <surname>Salomon</surname>
              <given-names>J</given-names>
            </name>
          </person-group>
          <article-title>Maneuvering through the stormy seas of digital transformation: the impact of empowering leadership on the AI readiness of enterprises</article-title>
          <source>Journal of Decision Systems</source>
          <year>2021</year>
          <month>01</month>
          <day>06</day>
          <fpage>1</fpage>
          <lpage>24</lpage>
          <pub-id pub-id-type="doi">10.1080/12460125.2020.1870065</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref33">
        <label>33</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Koch</surname>
              <given-names>M</given-names>
            </name>
            <name name-style="western">
              <surname>Schwabe</surname>
              <given-names>G</given-names>
            </name>
            <name name-style="western">
              <surname>Briggs</surname>
              <given-names>RO</given-names>
            </name>
          </person-group>
          <article-title>CSCW and Social Computing</article-title>
          <source>Bus Inf Syst Eng</source>
          <year>2015</year>
          <month>3</month>
          <day>3</day>
          <volume>57</volume>
          <issue>3</issue>
          <fpage>149</fpage>
          <lpage>153</lpage>
          <pub-id pub-id-type="doi">10.1007/s12599-015-0376-2</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref34">
        <label>34</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Lewkowicz</surname>
              <given-names>M</given-names>
            </name>
            <name name-style="western">
              <surname>Liron</surname>
              <given-names>R</given-names>
            </name>
          </person-group>
          <article-title>The Missing “Turn to Practice” in the Digital Transformation of Industry</article-title>
          <source>Comput Supported Coop Work</source>
          <year>2019</year>
          <month>4</month>
          <day>24</day>
          <volume>28</volume>
          <issue>3-4</issue>
          <fpage>655</fpage>
          <lpage>683</lpage>
          <pub-id pub-id-type="doi">10.1007/s10606-019-09347-y</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref35">
        <label>35</label>
        <nlm-citation citation-type="confproc">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Mihailescu</surname>
              <given-names>M</given-names>
            </name>
            <name name-style="western">
              <surname>Mihailescu</surname>
              <given-names>D</given-names>
            </name>
          </person-group>
          <article-title>The emergence of digitalisation in the context of health care</article-title>
          <source>Proceedings of the 51st Hawaii International Conference on System Sciences</source>
          <year>2018</year>
          <conf-name>51st Hawaii International Conference on System Sciences</conf-name>
          <conf-date>January 3-6, 2018</conf-date>
          <conf-loc>Maui, HI</conf-loc>
          <pub-id pub-id-type="doi">10.24251/hicss.2018.387</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref36">
        <label>36</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Goh</surname>
              <given-names>JM</given-names>
            </name>
            <name name-style="western">
              <surname>Gao</surname>
              <given-names>G</given-names>
            </name>
            <name name-style="western">
              <surname>Agarwal</surname>
              <given-names>R</given-names>
            </name>
          </person-group>
          <article-title>Evolving Work Routines: Adaptive Routinization of Information Technology in Healthcare</article-title>
          <source>Inf Sys Res</source>
          <year>2011</year>
          <month>09</month>
          <volume>22</volume>
          <issue>3</issue>
          <fpage>565</fpage>
          <lpage>585</lpage>
          <pub-id pub-id-type="doi">10.1287/isre.1110.0365</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref37">
        <label>37</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Bygstad</surname>
              <given-names>B</given-names>
            </name>
            <name name-style="western">
              <surname>Øvrelid</surname>
              <given-names>E</given-names>
            </name>
            <name name-style="western">
              <surname>Lie</surname>
              <given-names>T</given-names>
            </name>
            <name name-style="western">
              <surname>Bergquist</surname>
              <given-names>M</given-names>
            </name>
          </person-group>
          <article-title>Developing and Organizing an Analytics Capability for Patient Flow in a General Hospital</article-title>
          <source>Inf Syst Front</source>
          <year>2019</year>
          <month>5</month>
          <day>4</day>
          <volume>22</volume>
          <issue>2</issue>
          <fpage>353</fpage>
          <lpage>364</lpage>
          <pub-id pub-id-type="doi">10.1007/s10796-019-09920-2</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref38">
        <label>38</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Frick</surname>
              <given-names>N</given-names>
            </name>
            <name name-style="western">
              <surname>Brünker</surname>
              <given-names>F</given-names>
            </name>
            <name name-style="western">
              <surname>Ross</surname>
              <given-names>B</given-names>
            </name>
            <name name-style="western">
              <surname>Stieglitz</surname>
              <given-names>S</given-names>
            </name>
          </person-group>
          <article-title>Der Einsatz von künstlicher Intelligenz zur Verbesserung des Incident Managements</article-title>
          <source>HMD</source>
          <year>2019</year>
          <month>2</month>
          <day>15</day>
          <volume>56</volume>
          <issue>2</issue>
          <fpage>357</fpage>
          <lpage>369</lpage>
          <pub-id pub-id-type="doi">10.1365/s40702-019-00505-w</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref39">
        <label>39</label>
        <nlm-citation citation-type="confproc">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Frick</surname>
              <given-names>N</given-names>
            </name>
            <name name-style="western">
              <surname>Brünker</surname>
              <given-names>F</given-names>
            </name>
            <name name-style="western">
              <surname>Ross</surname>
              <given-names>B</given-names>
            </name>
            <name name-style="western">
              <surname>Stieglitz</surname>
              <given-names>S</given-names>
            </name>
          </person-group>
          <article-title>Design requirements for AI-based services enriching legacy information systems in enterprises: A managerial perspective</article-title>
          <source>Proceedings of the 31st Australasian Conference on Information Systems (ACIS)</source>
          <year>2020</year>
          <month>12</month>
          <day>03</day>
          <conf-name>31st Australasian Conference on Information Systems (ACIS)</conf-name>
          <conf-date>December 1-4, 2020</conf-date>
          <conf-loc>Wellington, New Zealand</conf-loc>
        </nlm-citation>
      </ref>
      <ref id="ref40">
        <label>40</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Agarwal</surname>
              <given-names>R</given-names>
            </name>
            <name name-style="western">
              <surname>Gao</surname>
              <given-names>G</given-names>
            </name>
            <name name-style="western">
              <surname>DesRoches</surname>
              <given-names>C</given-names>
            </name>
            <name name-style="western">
              <surname>Jha</surname>
              <given-names>AK</given-names>
            </name>
          </person-group>
          <article-title>Research Commentary—The Digital Transformation of Healthcare: Current Status and the Road Ahead</article-title>
          <source>Inf Sys Res</source>
          <year>2010</year>
          <month>12</month>
          <volume>21</volume>
          <issue>4</issue>
          <fpage>796</fpage>
          <lpage>809</lpage>
          <pub-id pub-id-type="doi">10.1287/isre.1100.0327</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref41">
        <label>41</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Häyrinen</surname>
              <given-names>K</given-names>
            </name>
            <name name-style="western">
              <surname>Saranto</surname>
              <given-names>K</given-names>
            </name>
            <name name-style="western">
              <surname>Nykänen</surname>
              <given-names>P</given-names>
            </name>
          </person-group>
          <article-title>Definition, structure, content, use and impacts of electronic health records: a review of the research literature</article-title>
          <source>Int J Med Inform</source>
          <year>2008</year>
          <month>05</month>
          <volume>77</volume>
          <issue>5</issue>
          <fpage>291</fpage>
          <lpage>304</lpage>
          <pub-id pub-id-type="doi">10.1016/j.ijmedinf.2007.09.001</pub-id>
          <pub-id pub-id-type="medline">17951106</pub-id>
          <pub-id pub-id-type="pii">S1386-5056(07)00168-2</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref42">
        <label>42</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Moro Visconti</surname>
              <given-names>R</given-names>
            </name>
            <name name-style="western">
              <surname>Martiniello</surname>
              <given-names>L</given-names>
            </name>
          </person-group>
          <article-title>Smart hospitals and patient-centered governance</article-title>
          <source>COC</source>
          <year>2019</year>
          <month>2</month>
          <day>27</day>
          <volume>16</volume>
          <issue>2</issue>
          <fpage>83</fpage>
          <lpage>96</lpage>
          <pub-id pub-id-type="doi">10.22495/cocv16i2art9</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref43">
        <label>43</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Moro Visconti</surname>
              <given-names>R</given-names>
            </name>
            <name name-style="western">
              <surname>Morea</surname>
              <given-names>D</given-names>
            </name>
          </person-group>
          <article-title>Healthcare Digitalization and Pay-For-Performance Incentives in Smart Hospital Project Financing</article-title>
          <source>Int J Environ Res Public Health</source>
          <year>2020</year>
          <month>03</month>
          <day>30</day>
          <volume>17</volume>
          <issue>7</issue>
          <comment>
            <ext-link ext-link-type="uri" xlink:type="simple" xlink:href="https://www.mdpi.com/resolver?pii=ijerph17072318"/>
          </comment>
          <pub-id pub-id-type="doi">10.3390/ijerph17072318</pub-id>
          <pub-id pub-id-type="medline">32235517</pub-id>
          <pub-id pub-id-type="pii">ijerph17072318</pub-id>
          <pub-id pub-id-type="pmcid">PMC7177756</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref44">
        <label>44</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Bullen</surname>
              <given-names>M</given-names>
            </name>
            <name name-style="western">
              <surname>Hughes</surname>
              <given-names>T</given-names>
            </name>
            <name name-style="western">
              <surname>Marshall</surname>
              <given-names>J</given-names>
            </name>
          </person-group>
          <article-title>The Evolution of Nice Medtech Innovation Briefings And Their Associated Technologies</article-title>
          <source>Value in Health</source>
          <year>2017</year>
          <month>10</month>
          <volume>20</volume>
          <issue>9</issue>
          <fpage>A595</fpage>
          <pub-id pub-id-type="doi">10.1016/j.jval.2017.08.1114</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref45">
        <label>45</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Ayal</surname>
              <given-names>M</given-names>
            </name>
            <name name-style="western">
              <surname>Seidman</surname>
              <given-names>A</given-names>
            </name>
          </person-group>
          <article-title>An Empirical Investigation of the Value of Integrating Enterprise Information Systems: The Case of Medical Imaging Informatics</article-title>
          <source>J Manag Inf Sys</source>
          <year>2014</year>
          <month>12</month>
          <day>08</day>
          <volume>26</volume>
          <issue>2</issue>
          <fpage>43</fpage>
          <lpage>68</lpage>
          <pub-id pub-id-type="doi">10.2753/mis0742-1222260203</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref46">
        <label>46</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Jack</surname>
              <given-names>E</given-names>
            </name>
            <name name-style="western">
              <surname>Powers</surname>
              <given-names>T</given-names>
            </name>
          </person-group>
          <article-title>Volume Flexible Strategies in Health Services: A Research Framework</article-title>
          <source>Prod Oper Manag</source>
          <year>2009</year>
          <volume>13</volume>
          <issue>3</issue>
          <fpage>244</fpage>
          <pub-id pub-id-type="doi">10.1111/j.1937-5956.2004.tb00508.x</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref47">
        <label>47</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Khoumbati</surname>
              <given-names>K</given-names>
            </name>
            <name name-style="western">
              <surname>Themistocleous</surname>
              <given-names>M</given-names>
            </name>
            <name name-style="western">
              <surname>Irani</surname>
              <given-names>Z</given-names>
            </name>
          </person-group>
          <article-title>Evaluating the Adoption of Enterprise Application Integration in Health-Care Organizations</article-title>
          <source>J Manag Inf Sys</source>
          <year>2014</year>
          <month>12</month>
          <day>08</day>
          <volume>22</volume>
          <issue>4</issue>
          <fpage>69</fpage>
          <lpage>108</lpage>
          <pub-id pub-id-type="doi">10.2753/mis0742-1222220404</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref48">
        <label>48</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Eden</surname>
              <given-names>R</given-names>
            </name>
            <name name-style="western">
              <surname>Burton-Jones</surname>
              <given-names>A</given-names>
            </name>
            <name name-style="western">
              <surname>Casey</surname>
              <given-names>V</given-names>
            </name>
            <name name-style="western">
              <surname>Draheim</surname>
              <given-names>M</given-names>
            </name>
          </person-group>
          <article-title>Digital Transformation Requires Workforce Transformation</article-title>
          <source>MISQE</source>
          <year>2019</year>
          <month>3</month>
          <day>1</day>
          <volume>18</volume>
          <issue>1</issue>
          <pub-id pub-id-type="doi">10.17705/2msqe.00005</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref49">
        <label>49</label>
        <nlm-citation citation-type="confproc">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Kretzer</surname>
              <given-names>M</given-names>
            </name>
            <name name-style="western">
              <surname>Gaß</surname>
              <given-names>O</given-names>
            </name>
            <name name-style="western">
              <surname>Mädche</surname>
              <given-names>A</given-names>
            </name>
          </person-group>
          <article-title>Design Principles for Diffusion of Reports and Innovative Use of Business Intelligence Platforms</article-title>
          <year>2015</year>
          <conf-name>WI 2015, the 12th International Conference on Wirtschaftsinformatik</conf-name>
          <conf-date>March 4-6, 2015</conf-date>
          <conf-loc>Osnabrück, Germany</conf-loc>
          <fpage>46</fpage>
        </nlm-citation>
      </ref>
      <ref id="ref50">
        <label>50</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Baiyere</surname>
              <given-names>A</given-names>
            </name>
            <name name-style="western">
              <surname>Salmela</surname>
              <given-names>H</given-names>
            </name>
            <name name-style="western">
              <surname>Tapanainen</surname>
              <given-names>T</given-names>
            </name>
          </person-group>
          <article-title>Digital transformation and the new logics of business process management</article-title>
          <source>Eur J Inf Syst</source>
          <year>2020</year>
          <month>03</month>
          <day>01</day>
          <volume>29</volume>
          <issue>3</issue>
          <fpage>238</fpage>
          <lpage>259</lpage>
          <pub-id pub-id-type="doi">10.1080/0960085x.2020.1718007</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref51">
        <label>51</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Broadbent</surname>
              <given-names>M</given-names>
            </name>
            <name name-style="western">
              <surname>Weill</surname>
              <given-names>P</given-names>
            </name>
            <name name-style="western">
              <surname>Clair</surname>
              <given-names>DS</given-names>
            </name>
          </person-group>
          <article-title>The Implications of Information Technology Infrastructure for Business Process Redesign</article-title>
          <source>MIS Q</source>
          <year>1999</year>
          <month>06</month>
          <volume>23</volume>
          <issue>2</issue>
          <fpage>159</fpage>
          <pub-id pub-id-type="doi">10.2307/249750</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref52">
        <label>52</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Bygstad</surname>
              <given-names>B</given-names>
            </name>
            <name name-style="western">
              <surname>Øvrelid</surname>
              <given-names>E</given-names>
            </name>
          </person-group>
          <article-title>Architectural alignment of process innovation and digital infrastructure in a high-tech hospital</article-title>
          <source>Eur J Inf Syst</source>
          <year>2020</year>
          <month>02</month>
          <day>27</day>
          <volume>29</volume>
          <issue>3</issue>
          <fpage>220</fpage>
          <lpage>237</lpage>
          <pub-id pub-id-type="doi">10.1080/0960085x.2020.1728201</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref53">
        <label>53</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Stieglitz</surname>
              <given-names>S</given-names>
            </name>
            <name name-style="western">
              <surname>Mirbabaie</surname>
              <given-names>M</given-names>
            </name>
            <name name-style="western">
              <surname>Kroll</surname>
              <given-names>T</given-names>
            </name>
            <name name-style="western">
              <surname>Marx</surname>
              <given-names>J</given-names>
            </name>
          </person-group>
          <article-title>“Silence” as a strategy during a corporate crisis – the case of Volkswagen’s “Dieselgate”</article-title>
          <source>INTR</source>
          <year>2019</year>
          <month>08</month>
          <day>05</day>
          <volume>29</volume>
          <issue>4</issue>
          <fpage>921</fpage>
          <lpage>939</lpage>
          <pub-id pub-id-type="doi">10.1108/intr-05-2018-0197</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref54">
        <label>54</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Mirbabaie</surname>
              <given-names>M</given-names>
            </name>
            <name name-style="western">
              <surname>Bunker</surname>
              <given-names>D</given-names>
            </name>
            <name name-style="western">
              <surname>Stieglitz</surname>
              <given-names>S</given-names>
            </name>
            <name name-style="western">
              <surname>Marx</surname>
              <given-names>J</given-names>
            </name>
            <name name-style="western">
              <surname>Ehnis</surname>
              <given-names>C</given-names>
            </name>
          </person-group>
          <article-title>Social media in times of crisis: Learning from Hurricane Harvey for the coronavirus disease 2019 pandemic response</article-title>
          <source>J Inf Technol</source>
          <year>2020</year>
          <month>06</month>
          <day>09</day>
          <volume>35</volume>
          <issue>3</issue>
          <fpage>195</fpage>
          <lpage>213</lpage>
          <pub-id pub-id-type="doi">10.1177/0268396220929258</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref55">
        <label>55</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Abdel-Basset</surname>
              <given-names>M</given-names>
            </name>
            <name name-style="western">
              <surname>Chang</surname>
              <given-names>V</given-names>
            </name>
            <name name-style="western">
              <surname>Nabeeh</surname>
              <given-names>NA</given-names>
            </name>
          </person-group>
          <article-title>An intelligent framework using disruptive technologies for COVID-19 analysis</article-title>
          <source>Technol Forecast Soc Change</source>
          <year>2021</year>
          <month>02</month>
          <volume>163</volume>
          <fpage>120431</fpage>
          <comment>
            <ext-link ext-link-type="uri" xlink:type="simple" xlink:href="http://europepmc.org/abstract/MED/33162617"/>
          </comment>
          <pub-id pub-id-type="doi">10.1016/j.techfore.2020.120431</pub-id>
          <pub-id pub-id-type="medline">33162617</pub-id>
          <pub-id pub-id-type="pii">S0040-1625(20)31257-9</pub-id>
          <pub-id pub-id-type="pmcid">PMC7598374</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref56">
        <label>56</label>
        <nlm-citation citation-type="web">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Rechel</surname>
              <given-names>B</given-names>
            </name>
            <name name-style="western">
              <surname>Maresso</surname>
              <given-names>A</given-names>
            </name>
            <name name-style="western">
              <surname>Sagan</surname>
              <given-names>A</given-names>
            </name>
            <name name-style="western">
              <surname>Hernández-Quevedo</surname>
              <given-names>C</given-names>
            </name>
            <name name-style="western">
              <surname>Williams</surname>
              <given-names>G</given-names>
            </name>
            <name name-style="western">
              <surname>Richardson</surname>
              <given-names>E</given-names>
            </name>
            <name name-style="western">
              <surname>Jakubowski</surname>
              <given-names>E</given-names>
            </name>
            <name name-style="western">
              <surname>Nolte</surname>
              <given-names>E</given-names>
            </name>
          </person-group>
          <source>Organization and financing of public health services in Europe: Country reports</source>
          <year>2018</year>
          <access-date>2021-01-20</access-date>
          <publisher-loc>Copenhagen, Denmark</publisher-loc>
          <publisher-name>European Observatory on Health Systems and Policies</publisher-name>
          <comment>
            <ext-link ext-link-type="uri" xlink:type="simple" xlink:href="https://www.ncbi.nlm.nih.gov/books/NBK507325/pdf/Bookshelf_NBK507325.pdf">https://www.ncbi.nlm.nih.gov/books/NBK507325/pdf/Bookshelf_NBK507325.pdf</ext-link>
          </comment>
        </nlm-citation>
      </ref>
      <ref id="ref57">
        <label>57</label>
        <nlm-citation citation-type="web">
          <article-title>Coronavirus SARS-CoV-2: Chronik der bisherigen Maßnahmen</article-title>
          <source>Bundesministerium für Gesundheit</source>
          <year>2020</year>
          <access-date>2020-04-30</access-date>
          <comment>
            <ext-link ext-link-type="uri" xlink:type="simple" xlink:href="https://www.bundesgesundheitsministerium.de/coronavirus/chronik-coronavirus.html">https://www.bundesgesundheitsministerium.de/coronavirus/chronik-coronavirus.html</ext-link>
          </comment>
        </nlm-citation>
      </ref>
      <ref id="ref58">
        <label>58</label>
        <nlm-citation citation-type="web">
          <article-title>Deutsche Interdisziplinäre Vereinigung für Intensiv- und Notfallmedizin Intensivregister</article-title>
          <source>DIVI</source>
          <access-date>2020-04-30</access-date>
          <comment>
            <ext-link ext-link-type="uri" xlink:type="simple" xlink:href="https://www.intensivregister.de/#/intensivregister">https://www.intensivregister.de/#/intensivregister</ext-link>
          </comment>
        </nlm-citation>
      </ref>
      <ref id="ref59">
        <label>59</label>
        <nlm-citation citation-type="web">
          <article-title>Microsoft Teams</article-title>
          <source>Microsoft</source>
          <access-date>2020-04-26</access-date>
          <comment>
            <ext-link ext-link-type="uri" xlink:type="simple" xlink:href="https://www.microsoft.com/en-us/microsoft-365/microsoft-teams/group-chat-software">https://www.microsoft.com/en-us/microsoft-365/microsoft-teams/group-chat-software</ext-link>
          </comment>
        </nlm-citation>
      </ref>
      <ref id="ref60">
        <label>60</label>
        <nlm-citation citation-type="web">
          <article-title>Responding to COVID-19 together</article-title>
          <source>Microsoft</source>
          <access-date>2020-04-26</access-date>
          <comment>
            <ext-link ext-link-type="uri" xlink:type="simple" xlink:href="https://news.microsoft.com/covid-19-response/">https://news.microsoft.com/covid-19-response/</ext-link>
          </comment>
        </nlm-citation>
      </ref>
      <ref id="ref61">
        <label>61</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Qu</surname>
              <given-names>SQ</given-names>
            </name>
            <name name-style="western">
              <surname>Dumay</surname>
              <given-names>J</given-names>
            </name>
          </person-group>
          <article-title>The qualitative research interview</article-title>
          <source>Qualitative Res Acc &#38; Man</source>
          <year>2011</year>
          <month>08</month>
          <day>30</day>
          <volume>8</volume>
          <issue>3</issue>
          <fpage>238</fpage>
          <lpage>264</lpage>
          <pub-id pub-id-type="doi">10.1108/11766091111162070</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref62">
        <label>62</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Schilling</surname>
              <given-names>J</given-names>
            </name>
          </person-group>
          <article-title>On the Pragmatics of Qualitative Assessment</article-title>
          <source>Eur J Psychol Assess</source>
          <year>2006</year>
          <month>01</month>
          <volume>22</volume>
          <issue>1</issue>
          <fpage>28</fpage>
          <lpage>37</lpage>
          <pub-id pub-id-type="doi">10.1027/1015-5759.22.1.28</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref63">
        <label>63</label>
        <nlm-citation citation-type="book">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Mayring</surname>
              <given-names>P</given-names>
            </name>
          </person-group>
          <person-group person-group-type="editor">
            <name name-style="western">
              <surname>Bikner-Ahsbahs</surname>
              <given-names>A</given-names>
            </name>
            <name name-style="western">
              <surname>Knipping</surname>
              <given-names>C</given-names>
            </name>
            <name name-style="western">
              <surname>Presmeg</surname>
              <given-names>N</given-names>
            </name>
          </person-group>
          <article-title>Qualitative Content Analysis: Theoretical Background and Procedures</article-title>
          <source>Approaches to Qualitative Research in Mathematics Education. Advances in Mathematics Education</source>
          <year>2015</year>
          <publisher-loc>Dordrecht, the Netherlands</publisher-loc>
          <publisher-name>Springer</publisher-name>
          <fpage>365</fpage>
        </nlm-citation>
      </ref>
      <ref id="ref64">
        <label>64</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Mettler</surname>
              <given-names>T</given-names>
            </name>
            <name name-style="western">
              <surname>Sprenger</surname>
              <given-names>M</given-names>
            </name>
            <name name-style="western">
              <surname>Winter</surname>
              <given-names>R</given-names>
            </name>
          </person-group>
          <article-title>Service robots in hospitals: new perspectives on niche evolution and technology affordances</article-title>
          <source>Eur J Inf Syst</source>
          <year>2017</year>
          <month>12</month>
          <day>19</day>
          <volume>26</volume>
          <issue>5</issue>
          <fpage>451</fpage>
          <lpage>468</lpage>
          <pub-id pub-id-type="doi">10.1057/s41303-017-0046-1</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref65">
        <label>65</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Győrffy</surname>
              <given-names>Z</given-names>
            </name>
            <name name-style="western">
              <surname>Radó</surname>
              <given-names>N</given-names>
            </name>
            <name name-style="western">
              <surname>Mesko</surname>
              <given-names>B</given-names>
            </name>
          </person-group>
          <article-title>Digitally engaged physicians about the digital health transition</article-title>
          <source>PLoS One</source>
          <year>2020</year>
          <volume>15</volume>
          <issue>9</issue>
          <fpage>e0238658</fpage>
          <comment>
            <ext-link ext-link-type="uri" xlink:type="simple" xlink:href="https://dx.plos.org/10.1371/journal.pone.0238658"/>
          </comment>
          <pub-id pub-id-type="doi">10.1371/journal.pone.0238658</pub-id>
          <pub-id pub-id-type="medline">32986733</pub-id>
          <pub-id pub-id-type="pii">PONE-D-20-11916</pub-id>
          <pub-id pub-id-type="pmcid">PMC7521720</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref66">
        <label>66</label>
        <nlm-citation citation-type="confproc">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Aanestad</surname>
              <given-names>M</given-names>
            </name>
            <name name-style="western">
              <surname>Vassilakopoulou</surname>
              <given-names>P</given-names>
            </name>
          </person-group>
          <article-title>Collaborative Innovation in Healthcare: Boundary Resources for Peripheral Actors</article-title>
          <source>ICIS 2019 Proceedings</source>
          <year>2019</year>
          <conf-name>International Conference on Information Systems (ICIS) 2019</conf-name>
          <conf-date>December 15-18, 2019</conf-date>
          <conf-loc>Munich, Germany</conf-loc>
        </nlm-citation>
      </ref>
      <ref id="ref67">
        <label>67</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Lucas, Jr.</surname>
              <given-names>HC</given-names>
            </name>
            <name name-style="western">
              <surname>Agarwal</surname>
              <given-names>R</given-names>
            </name>
            <name name-style="western">
              <surname>Clemons</surname>
              <given-names>EK</given-names>
            </name>
            <name name-style="western">
              <surname>El Sawy</surname>
              <given-names>OA</given-names>
            </name>
            <name name-style="western">
              <surname>Weber</surname>
              <given-names>B</given-names>
            </name>
          </person-group>
          <article-title>Impactful Research on Transformational Information Technology:  An Opportunity to Inform New Audiences</article-title>
          <source>MISQ</source>
          <year>2013</year>
          <month>2</month>
          <day>2</day>
          <volume>37</volume>
          <issue>2</issue>
          <fpage>371</fpage>
          <lpage>382</lpage>
          <pub-id pub-id-type="doi">10.25300/misq/2013/37.2.03</pub-id>
        </nlm-citation>
      </ref>
    </ref-list>
  </back>
</article>
